5 research outputs found

    Fortalecimiento de la prestación de mecanismos de seguridad y salud en el trabajo para los empleados de Asvidas Palestina para el 2022.

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    Anexo 1 Aplicativo de encuesta online (Google Forms) 38Implementar en las organizaciones un buen sistema de gestión de seguridad y salud en el trabajo es fundamental para garantizar la calidad de vida de todos sus colaboradores, de allí la importancia de que se puedan prevenir y controlar los accidentes, enfermedades laborales, ausentismo, etc. razón por la cual en la en la empresa Asociación para la vida digna y solidaria Asvidas Palestina, entidad sin ánimo de lucro y cuyo objeto social es hacer valer los derechos de los niños y eliminar la vulneración de los mismos; cuenta con un SG-SST sin embargo presenta varias falencias que, si es necesario mitigar y contrarrestar para llevar un correcto proceso para la prevención de accidentes, enfermedades y poder mejorar la estabilidad, y el bienestar con unas condiciones favorables donde todos los colaboradores trabajen a gusto y de manera eficiente. El objetivo propuesto para contrarrestar la situación actual de la empresa es desarrollar una cultura de seguridad preventiva basada en la mejora continua con finalidad de poder anticipar, evaluar y controlar cualquier riesgo donde se pueda ver afectado el empleado.Implementing a good occupational health and safety management system in organizations is essential to guarantee the quality of life of all its collaborators, hence the importance of preventing and controlling accidents, occupational diseases, absenteeism, etc. which is why in the company Association for a dignified and supportive life Asvidas Palestina, a non-profit organization whose corporate purpose is to assert the rights of children and eliminate their violation; has a SG-SST, however, it has several shortcomings that, if necessary, mitigate and counteract in order to carry out a correct process for the prevention of accidents, illnesses and to be able to improve stability and well-being with favorable conditions where all collaborators work together. tastefully and efficiently. The proposed objective to counteract the current situation of the company is to develop a culture of preventive safety based on continuous improvement in order to be able to anticipate, evaluate and control any risk where the employee may be affected

    LA INCLUSIÓN EDUCATIVA EN LA PERSPECTIVA INTERDISCIPLINARIA

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    SE DAN APORTACIONES QUE AYUDAN A COMPRENDER QUE ACCCIONES Y CAMBIOS TOMAR PARA MEJORAR LA EDUCACIÓN.EL LIBR PRESENTA DIVERSOS TRABAJOS QUE ABORDAN LA PROBLEMÁTICA DE LA EDUCACIÓN DESDE LA PERSPECTIVA INTERDISCIPLINARIA.NINGUN

    Cognitive decline in Huntington's disease expansion gene carriers

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    Optimization of adsorptive removal of α-toluic acid by CaO2 nanoparticles using response surface methodology

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    The present work addresses the optimization of process parameters for adsorptive removal of α-toluic acid by calcium peroxide (CaO2) nanoparticles using response surface methodology (RSM). CaO2 nanoparticles were synthesized by chemical precipitation method and confirmed by Transmission electron microscopy (TEM) and high-resolution TEM (HRTEM) analysis which shows the CaO2 nanoparticles size range of 5–15 nm. A series of batch adsorption experiments were performed using CaO2 nanoparticles to remove α-toluic acid from the aqueous solution. Further, an experimental based central composite design (CCD) was developed to study the interactive effect of CaO2 adsorbent dosage, initial concentration of α-toluic acid, and contact time on α-toluic acid removal efficiency (response) and optimization of the process. Analysis of variance (ANOVA) was performed to determine the significance of the individual and the interactive effects of variables on the response. The model predicted response showed a good agreement with the experimental response, and the coefficient of determination, (R2) was 0.92. Among the variables, the interactive effect of adsorbent dosage and the initial α-toluic acid concentration was found to have more influence on the response than the contact time. Numerical optimization of process by RSM showed the optimal adsorbent dosage, initial concentration of α-toluic acid, and contact time as 0.03 g, 7.06 g/L, and 34 min respectively. The predicted removal efficiency was 99.50%. The experiments performed under these conditions showed α-toluic acid removal efficiency up to 98.05%, which confirmed the adequacy of the model prediction

    Clinical and genetic characteristics of late-onset Huntington's disease

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    Background: The frequency of late-onset Huntington's disease (>59 years) is assumed to be low and the clinical course milder. However, previous literature on late-onset disease is scarce and inconclusive. Objective: Our aim is to study clinical characteristics of late-onset compared to common-onset HD patients in a large cohort of HD patients from the Registry database. Methods: Participants with late- and common-onset (30–50 years)were compared for first clinical symptoms, disease progression, CAG repeat size and family history. Participants with a missing CAG repeat size, a repeat size of ≤35 or a UHDRS motor score of ≤5 were excluded. Results: Of 6007 eligible participants, 687 had late-onset (11.4%) and 3216 (53.5%) common-onset HD. Late-onset (n = 577) had significantly more gait and balance problems as first symptom compared to common-onset (n = 2408) (P <.001). Overall motor and cognitive performance (P <.001) were worse, however only disease motor progression was slower (coefficient, −0.58; SE 0.16; P <.001) compared to the common-onset group. Repeat size was significantly lower in the late-onset (n = 40.8; SD 1.6) compared to common-onset (n = 44.4; SD 2.8) (P <.001). Fewer late-onset patients (n = 451) had a positive family history compared to common-onset (n = 2940) (P <.001). Conclusions: Late-onset patients present more frequently with gait and balance problems as first symptom, and disease progression is not milder compared to common-onset HD patients apart from motor progression. The family history is likely to be negative, which might make diagnosing HD more difficult in this population. However, the balance and gait problems might be helpful in diagnosing HD in elderly patients
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