44 research outputs found

    The Diversifying Experience Model::Taking a Broader Conceptual View of the Multiculturalism–Creativity Link

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    We examine the multiculturalism–creativity link from the perspective of diversifying experiences research. Multicultural experiences can be construed as diversifying experiences—highly unusual and unexpected events or situations (e.g., unusual educational experiences, early life adversity) that push individuals outside the frameworks of their ordinary everyday lives, forcing them to embrace new and uncommon ideas. Our review identifies a range of diversifying experiences (e.g., multicultural exposure, unexpected adversity, violations of expectations) that have been found to influence creativity. We introduce the Diversifying Experience Model (DEM), where we argue for a curvilinear relationship between diversifying experiences and creativity, whereby creativity improves as a result of moderate (but not low or high) levels of diversifying experiences. We also propose adaptive personal resources as the key moderator, and threat and challenge appraisals as the key mediators of the diversifying experience–creativity relation. When adaptive resources are high, moderate diversifying experiences are appraised primarily as a challenge, facilitating creativity, whereas when adaptive resources are low, moderate diversifying experiences are appraised primarily as a threat, derailing creativity. This broad and parsimonious theoretical framework can help clarify and expand research on when and why various diversifying experiences (including multicultural experiences) facilitate creativity. </jats:p

    Adaptive Appraisals of Anxiety Moderate the Association between Cortisol Reactivity and Performance in Salary Negotiations

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    Prior research suggests that stress can be harmful in high-stakes contexts such as negotiations. However, few studies actually measure stress physiologically during negotiations, nor do studies offer interventions to combat the potential negative effects of heightened physiological responses in negotiation contexts. In the current research, we offer evidence that the negative effects of cortisol increases on negotiation performance can be reduced through a reappraisal of anxiety manipulation. We experimentally induced adaptive appraisals by randomly assigning 97 male and female participants to receive either instructions to appraise their anxiety as beneficial to the negotiation or no specific instructions on how to appraise the situation. We also measured participants’ cortisol responses prior to and following the negotiation. Results revealed that cortisol increases were positively related to negotiation performance for participants who were told to view anxiety as beneficial, and not detrimental, for negotiation performance (appraisal condition). In contrast, cortisol increases were negatively related to negotiation performance for participants given no instructions on appraising their anxiety (control condition). These findings offer a means through which to combat the potentially deleterious effects of heightened cortisol reactivity on negotiation outcomes

    Examining the synergistic effects of a cognitive control video game and a home-based, self-administered non-invasive brain stimulation on alleviating depression : the DiSCoVeR trial protocol

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    Funding Information: Open Access funding enabled and organized by Projekt DEAL. The DisCoVeR project is funded by ERA NET NEURON. The NEURON ‘Network of European Funding for Neuroscience Research is established under the organization of the ERA-NET ‘European Research Area Networks’ of the European Commission. National funding agencies are the Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung [BMBF]) for LMU Munich, the Ministry of Health (MOH) for HUJI and Hadassah, the Swiss National Science Foundation (SNSF) for UNIGE and EPFL and the State Education and Development Agency (VIAA) of Latvia for RSU. Funding Information: This project was funded by the European Research Area Network (ERA-NET) NEURON 2018 Mental Disorders program. Publisher Copyright: © 2022, The Author(s).Enhanced behavioral interventions are gaining increasing interest as innovative treatment strategies for major depressive disorder (MDD). In this study protocol, we propose to examine the synergistic effects of a self-administered home-treatment, encompassing transcranial direct current stimulation (tDCS) along with a video game based training of attentional control. The study is designed as a two-arm, double-blind, randomized and placebo-controlled multi-center trial (ClinicalTrials.gov: NCT04953208). At three study sites (Israel, Latvia, and Germany), 114 patients with a primary diagnosis of MDD undergo 6 weeks of intervention (30 × 30 min sessions). Patients assigned to the intervention group receive active tDCS (anode F3 and cathode F4; 2 mA intensity) and an action-like video game, while those assigned to the control group receive sham tDCS along with a control video game. An electrode-positioning algorithm is used to standardize tDCS electrode positioning. Participants perform their designated treatment at the clinical center (sessions 1-5) and continue treatment at home under remote supervision (sessions 6-30). The endpoints are feasibility (primary) and safety, treatment efficacy (secondary, i.e., change of Montgomery-Åsberg Depression Rating Scale (MADRS) scores at week six from baseline, clinical response and remission, measures of social, occupational, and psychological functioning, quality of life, and cognitive control (tertiary). Demonstrating the feasibility, safety, and efficacy of this novel combined intervention could expand the range of available treatments for MDD to neuromodulation enhanced interventions providing cost-effective, easily accessible, and low-risk treatment options.ClinicalTrials.gov: NCT04953208.publishersversionPeer reviewe

    USP27X variants underlying X-linked intellectual disability disrupt protein function via distinct mechanisms

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    Neurodevelopmental disorders with intellectual disability (ND/ID) are a heterogeneous group of diseases driving lifelong deficits in cognition and behavior with no definitive cure. X-linked intellectual disability disorder 105 (XLID105, #300984; OMIM) is a ND/ID driven by hemizygous variants in the USP27X gene encoding a protein deubiquitylase with a role in cell proliferation and neural development. Currently, only four genetically diagnosed individuals from two unrelated families have been described with limited clinical data. Furthermore, the mechanisms underlying the disorder are unknown. Here, we report 10 new XLID105 individuals from nine families and determine the impact of gene variants on USP27X protein function. Using a combination of clinical genetics, bioinformatics, biochemical, and cell biology approaches, we determined that XLID105 variants alter USP27X protein biology via distinct mechanisms including changes in developmentally relevant protein-protein interactions and deubiquitylating activity. Our data better define the phenotypic spectrum of XLID105 and suggest that XLID105 is driven by USP27X functional disruption. Understanding the pathogenic mechanisms of XLID105 variants will provide molecular insight into USP27X biology and may create the potential for therapy development.</p

    Inducing gender/professional identity compatibility promotes women's compensation requests.

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    In this paper, I examine whether inducing gender/professional identity compatibility prior to a self-advocacy negotiation, may enhance women's assertiveness in a compensation negotiation and mitigate potential social backlash concerns for assertiveness. In two experimental lab studies where women negotiated with a male counterpart as sellers and job candidates, I found evidence supporting the causal link between state gender/profession identity integration and higher levels of assertiveness in women's self-advocacy compensation negotiations

    The double-edge of similarity and difference mindsets: What comparison mindsets do depends on whether self or group representations are focal

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    Past work has argued that comparison mindsets affect stereotyping: perceivers in a difference mindset stereotype less than those in a similarity mindset, contrasting their judgments of an individual away from their representation of the group. Here, we argue that the self can also act as a reference point, implying that the impact of comparison mindsets depends on what is focal. In two studies manipulating comparison mindsets and activated representations, we find support for our claims that a difference (compared to similarity) mindset leads to less stereotyping and greater social projection when group representations are focal but to more stereotyping and less projection when self representations are focal. © 2012 Elsevier Inc. All rights reserved
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