4,755 research outputs found
Multi-frame-based Cross-domain Image Denoising for Low-dose Computed Tomography
Computed tomography (CT) has been used worldwide for decades as one of the
most important non-invasive tests in assisting diagnosis. However, the ionizing
nature of X-ray exposure raises concerns about potential health risks such as
cancer. The desire for lower radiation dose has driven researchers to improve
the reconstruction quality, especially by removing noise and artifacts.
Although previous studies on low-dose computed tomography (LDCT) denoising have
demonstrated the effectiveness of learning-based methods, most of them were
developed on the simulated data collected using Radon transform. However, the
real-world scenario significantly differs from the simulation domain, and the
joint optimization of denoising with modern CT image reconstruction pipeline is
still missing. In this paper, for the commercially available third-generation
multi-slice spiral CT scanners, we propose a two-stage method that better
exploits the complete reconstruction pipeline for LDCT denoising across
different domains. Our method makes good use of the high redundancy of both the
multi-slice projections and the volumetric reconstructions while avoiding the
collapse of information in conventional cascaded frameworks. The dedicated
design also provides a clearer interpretation of the workflow. Through
extensive evaluations, we demonstrate its superior performance against
state-of-the-art methods
Security Analysis and Improvements of Session Key Establishment for Clustered Sensor Networks
WSN (wireless sensor network) is one of the main technologies in IoT (Internet of Things) applications or services. To date, several schemes have been proposed to establish a pair-wise key between two nodes in WSN, and most of them are designed to establish long-term keys used throughout the network lifetime. However, in the near future, if WSN will be used for information infrastructures in various fields such as manufacturing, distribution, or public facilities management and its life cycle can be as long as that of other common networks, it will definitely be advantageous in terms of security to encrypt messages using session keys instead of long-term keys. In this paper, we propose a session key establishment scheme for clustered sensor networks that is based on elliptic curve Diffie-Hellman (ECDH) key exchange and hash chain. The proposed scheme eliminates vulnerabilities of existing schemes for WSN and has improved security. The proposed scheme is efficient in terms of energy costs compared to related schemes
Falciform Ligament Abscess after Omphalitis: Report of a Case
A falciform ligament abscess is a rare type of intra-abdominal abscess. A 2-yr-old male, who had omphalitis two months previously, presented with a fever and right upper quadrant abdominal pain. The ultrasound and CT scan showed an abdominal wall abscess located anterior to the liver, which was refractory to conservative management with percutaneous draninage and antibiotics. On the third recurrence, surgical exploration was performed and revealed an abscess arising from the falciform ligament; the falciform ligament was excised. A follow up ultrasound confirmed complete resolution of the abscess with no further recurrence
Optical spectroscopic investigation on the coupling of electronic and magnetic structure in multiferroic hexagonal RMnO3 (R = Gd, Tb, Dy, and Ho) thin films
We investigated the effects of temperature and magnetic field on the
electronic structure of hexagonal RMnO3 (R = Gd, Tb, Dy, and Ho) thin films
using optical spectroscopy. As the magnetic ordering of the system was
disturbed, a systematic change in the electronic structure was commonly
identified in this series. The optical absorption peak near 1.7 eV showed an
unexpectedly large shift of more than 150 meV from 300 K to 15 K, accompanied
by an anomaly of the shift at the Neel temperature. The magnetic field
dependent measurement clearly revealed a sizable shift of the corresponding
peak when a high magnetic field was applied. Our findings indicated strong
coupling between the magnetic ordering and the electronic structure in the
multiferroic hexagonal RMnO3 compounds.Comment: 16 pages including 4 figure
Recent advances in the imaging of hepatocellular carcinoma
The role of imaging is crucial for the surveillance, diagnosis, staging and treatment monitoring of hepatocellular carcinoma (HCC). Over the past few years, considerable technical advances were made in imaging of HCCs. New imaging technology, however, has introduced new challenges in our clinical practice. In this article, the current status of clinical imaging techniques for HCC is addressed. The diagnostic performance of imaging techniques in the context of recent clinical guidelines is also presented
Agaricus blazei Extract Induces Apoptosis through ROS-Dependent JNK Activation Involving the Mitochondrial Pathway and Suppression of Constitutive NF-κB in THP-1 Cells
Agaricus blazei is widely accepted as a traditional medicinal mushroom, and it has been known to exhibit immunostimulatory and anti-cancer activity. However, the apoptotic mechanism in cancer cells is poorly understood. In this study, we have investigated whether A. blazei extract (ABE) exerts antiproliferative and apoptotic effects in human leukemic THP-1 cells. We observed that ABE-induced apoptosis is associated with the mitochondrial pathway, which is mediated by reactive oxygen species (ROS) generation and prolonged c-Jun N-terminal kinase (JNK) activation. In addition, the ABE treatment resulted in the accumulation of cytochrome c in the cytoplasm, an increase in caspase activity, and an upregulation of Bax and Bad. With those results in mind, we found that ABE decreases constitutive NF-κB activation and NF-κB-regulated gene products such as IAP-1 and -2. We concluded that ABE induces apoptosis with ROS-dependent JNK activation and constitutive activated NF-κB inhibition in THP-1 cells
- …