Text pre-processing tool to increase the exactness of experimental results in summarization solutions

For years, and nowadays even more because of the ease of access to information, countless scientific documents that cover all branches of human knowledge are generated. These documents, consisting mostly of text, are stored in digital libraries that are increasingly consenting access and manipulation. This has allowed these repositories of documents to be used for research work of great interest, particularly those related to evaluation of automatic summaries through experimentation. In this area of computer science, the experimental results of many of the published works are obtained using document collections, some known and others not so much, but without specifying all the special considerations to achieve said results. This produces an unfair competition in the realization of experiments when comparing results and does not allow to be objective in the obtained conclusions. This paper presents a text document manipulation tool to increase the exactness of results when obtaining, evaluating and comparing automatic summaries from different corpora. This work has been motivated by the need to have a tool that allows to process documents, split their content properly and make sure that each text snippet does not lose its contextual information. Applying the model proposed to a set of free-access scientific papers has been successful.XV Workshop Bases de Datos y Minería de Datos (WBDDM)Red de Universidades con Carreras en Informática (RedUNCI

Text pre-processing tool to increase the exactness of experimental results in summarization solutions

For years, and nowadays even more because of the ease of access to information, countless scientific documents that cover all branches of human knowledge are generated. These documents, consisting mostly of text, are stored in digital libraries that are increasingly consenting access and manipulation. This has allowed these repositories of documents to be used for research work of great interest, particularly those related to evaluation of automatic summaries through experimentation. In this area of computer science, the experimental results of many of the published works are obtained using document collections, some known and others not so much, but without specifying all the special considerations to achieve said results. This produces an unfair competition in the realization of experiments when comparing results and does not allow to be objective in the obtained conclusions. This paper presents a text document manipulation tool to increase the exactness of results when obtaining, evaluating and comparing automatic summaries from different corpora. This work has been motivated by the need to have a tool that allows to process documents, split their content properly and make sure that each text snippet does not lose its contextual information. Applying the model proposed to a set of free-access scientific papers has been successful.XV Workshop Bases de Datos y Minería de Datos (WBDDM)Red de Universidades con Carreras en Informática (RedUNCI

Implementación de un sistema piloto de telemedicina en Mendoza

La telemedicina se caracteriza por utilizar las nuevas tecnologías informáticas y de comunicaciones para ofrecer acceso a la salud, independientemente del lugar donde se encuentre quien lo necesite. Este informe hace referencia a la utilización de dichas tecnologías al plantear el desarrollo e implementación de un sistema de telemedicina, para la transmisión y monitoreo de señales cardíacas, con la finalidad de suplir atención sanitaria en comunidades rurales, donde la distancia constituye un factor crítico. Los actores principales que conforman la arquitectura tecnológica y la red son: 1) Sistemas Embebidos, 2) Adquisidores de Señales Cardíacas Inalámbricos, 3) Computadoras Personales PC, 4) Asistentes Digitales Personales PDA 5) Software y 6) Infraestructura de Comunicación. Según se agrupen estos elementos es posible distinguir tres alternativas o unidades, que de acuerdo con sus ventajas y desventajas serían aplicables a diferentes usos. En todos los casos la transmisión es realizada hacia un servidor, donde los datos correspondientes a las variables biológicas son almacenados en bases de datos, pudiendo ser luego objeto de análisis y diagnóstico. Hasta el momento los resultados obtenidos en ambas alternativas han sido satisfactorios, tanto en la fabricación del adquisidor de señales y como en la transmisión de los datos.Telemedicine is characterized for offering access to healthcare by using the new computer and communication technologies, independently of where the individual in need is. This report refers to the use of these technologies while outlining the development and implementation of a system for the monitoring and transmission cardiac signals with the purpose of replacing sanitary services in rural communities, where distance constitutes a critical factor. The main elements that make up the technological architecture and the network are: 1) the embedded systems, 2) Wireless Cardiac signal data loggers 3) Personal Computers PCs, 4) Personal Digital Assistants PDA, 5) Software and 6) Communication Infrastructure. Depending on the way we group these elements it is possible to distinguish three different alternatives, each one with its pros and cons for different applications. In all these alternatives, the data is sent to a server where the data of the biological variables are stored in a database, subject to later analysis and diagnosis. So far, the results obtained have been satisfactory both in the manufacturing of the data logger as well as the data transmissionWorkshop de Arquitecturas, Redes y Sistemas Operativos (WARSO)Red de Universidades con Carreras en Informática (RedUNCI

Implementación de un sistema piloto de telemedicina en Mendoza

La telemedicina se caracteriza por utilizar las nuevas tecnologías informáticas y de comunicaciones para ofrecer acceso a la salud, independientemente del lugar donde se encuentre quien lo necesite. Este informe hace referencia a la utilización de dichas tecnologías al plantear el desarrollo e implementación de un sistema de telemedicina, para la transmisión y monitoreo de señales cardíacas, con la finalidad de suplir atención sanitaria en comunidades rurales, donde la distancia constituye un factor crítico. Los actores principales que conforman la arquitectura tecnológica y la red son: 1) Sistemas Embebidos, 2) Adquisidores de Señales Cardíacas Inalámbricos, 3) Computadoras Personales PC, 4) Asistentes Digitales Personales PDA 5) Software y 6) Infraestructura de Comunicación. Según se agrupen estos elementos es posible distinguir tres alternativas o unidades, que de acuerdo con sus ventajas y desventajas serían aplicables a diferentes usos. En todos los casos la transmisión es realizada hacia un servidor, donde los datos correspondientes a las variables biológicas son almacenados en bases de datos, pudiendo ser luego objeto de análisis y diagnóstico. Hasta el momento los resultados obtenidos en ambas alternativas han sido satisfactorios, tanto en la fabricación del adquisidor de señales y como en la transmisión de los datos.Telemedicine is characterized for offering access to healthcare by using the new computer and communication technologies, independently of where the individual in need is. This report refers to the use of these technologies while outlining the development and implementation of a system for the monitoring and transmission cardiac signals with the purpose of replacing sanitary services in rural communities, where distance constitutes a critical factor. The main elements that make up the technological architecture and the network are: 1) the embedded systems, 2) Wireless Cardiac signal data loggers 3) Personal Computers PCs, 4) Personal Digital Assistants PDA, 5) Software and 6) Communication Infrastructure. Depending on the way we group these elements it is possible to distinguish three different alternatives, each one with its pros and cons for different applications. In all these alternatives, the data is sent to a server where the data of the biological variables are stored in a database, subject to later analysis and diagnosis. So far, the results obtained have been satisfactory both in the manufacturing of the data logger as well as the data transmissionWorkshop de Arquitecturas, Redes y Sistemas Operativos (WARSO)Red de Universidades con Carreras en Informática (RedUNCI

Holographic Fabry–Perot spectrometer

We propose a spectrum analyzer based on the properties of a hologram recorded with the field transmitted by a Fabry-Perot etalon. The spectral response of this holographic Fabry-Perot spectrometer (HFPS) is analytically investigated in the paraxial approximation and compared with a conventional Fabry-Perot etalon of similar characteristics. We demonstrate that the resolving power is twice increased and the free spectral range (FSR) is reduced to one-half. The proposed spectrometer could improve the operational performance of the etalon because it can exhibit high efficiency and it would be insensible to environmental conditions such as temperature and vibrations. Our analysis also extends to another variant of the HFPS based on holographic multiplexing of the transmitted field of a Fabry-Perot etalon. This device increases the FSR, keeping the same HFPS performance. © 2011 Optical Society of America.We thank A. Cámara Iglesias for valuable discussions and advice. Financial support from the Spanish Ministry of Science and Innovation under project TEC 2008-04105 is acknowledged.Peer Reviewe

Text pre-processing tool to increase the exactness of experimental results in summarization solutions

For years, and nowadays even more because of the ease of access to information, countless scientific documents that cover all branches of human knowledge are generated. These documents, consisting mostly of text, are stored in digital libraries that are increasingly consenting access and manipulation. This has allowed these repositories of documents to be used for research work of great interest, particularly those related to evaluation of automatic summaries through experimentation. In this area of computer science, the experimental results of many of the published works are obtained using document collections, some known and others not so much, but without specifying all the special considerations to achieve said results. This produces an unfair competition in the realization of experiments when comparing results and does not allow to be objective in the obtained conclusions. This paper presents a text document manipulation tool to increase the exactness of results when obtaining, evaluating and comparing automatic summaries from different corpora. This work has been motivated by the need to have a tool that allows to process documents, split their content properly and make sure that each text snippet does not lose its contextual information. Applying the model proposed to a set of free-access scientific papers has been successful.XV Workshop Bases de Datos y Minería de Datos (WBDDM)Red de Universidades con Carreras en Informática (RedUNCI

Breast cancer PAM50 signature: correlation and concordance between RNA-Seq and digital multiplexed gene expression technologies in a triple negative breast cancer series

[Background]: Full RNA-Seq is a fundamental research tool for whole transcriptome analysis. However, it is too costly and time consuming to be used in routine clinical practice. We evaluated the transcript quantification agreement between RNA-Seq and a digital multiplexed gene expression platform, and the subtype call after running the PAM50 assay in a series of breast cancer patients classified as triple negative by IHC/FISH. The goal of this study is to analyze the concordance between both expression platforms overall, and for calling PAM50 triple negative breast cancer intrinsic subtypes in particular.[Results]: The analyses were performed in paraffin-embedded tissues from 96 patients recruited in a multicenter, prospective, non-randomized neoadjuvant triple negative breast cancer trial (NCT01560663). Pre-treatment core biopsies were obtained following clinical practice guidelines and conserved as FFPE for further RNA extraction. PAM50 was performed on both digital multiplexed gene expression and RNA-Seq platforms. Subtype assignment was based on the nearest centroid classification following this procedure for both platforms and it was concordant on 96% of the cases (N = 96). In four cases, digital multiplexed gene expression analysis and RNA-Seq were discordant. The Spearman correlation to each of the centroids and the risk of recurrence were above 0.89 in both platforms while the agreement on Proliferation Score reached up to 0.97. In addition, 82% of the individual PAM50 genes showed a correlation coefficient > 0.80.[Conclusions]: In our analysis, the subtype calling in most of the samples was concordant in both platforms and the potential discordances had reduced clinical implications in terms of prognosis. If speed and cost are the main driving forces then the preferred technique is the digital multiplexed platform, while if whole genome patterns and subtype are the driving forces, then RNA-Seq is the preferred method.M.M was supported by two research grants from Ministry of Economy and Competitiveness ISCIII-FIS grants (PI 12/02684): “Predictores genómicos de respuesta a la quimioterapia neoadyuvante con docetaxel-carboplatino en pacientes con cáncer de mama triple negativo”/“Genomic predictors of response to neoadjuvant chemotherapy with docetaxel-carboplatin in patients with triple negative breast cancer”; and (PI 15/00117): “Cáncer de mama triple negative: Predicción de respuesta a docetaxel-carboplatino neoadyuvante mediante caracterización de TILs y firmas inmunes basadas en secuenciación masiva de RNA”/” Triple negative breast cancer: Prediction of response to neoadjuvant docetaxel-carboplatin by characterization of TILs and immune signatures based on massive RNA sequencing”. C.M.P was supported by funds from the NCI Breast SPORE program (P50-CA58223).Peer reviewe

Processament del senyal - Col.lecció de Problemes

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