Case Report : cutaneous melanocytic schwannoma with concomitant melanocytoma in a canine

DATA AVAILABILITY : All data underlying the results are available as part of the article and no additional source data are required.REPORTING GUIDELINES : Figshare: CARE checklist for ‘Case Report: Cutaneous melanocytic schwannoma with concomitant melanocytoma in a canine’. https://doi.org/10.6084/m9.figshare.23896725 Data are available under the terms of the Creative Commons Attribution 4.0 International license (CC-BY 4.0).Schwannoma is a nerve sheath tumour arising from differentiated Schwann cells, and melanocytic schwannoma (MS) is a rare variant where the Schwan cells produce melanin pigment. MS is typically associated with spinal nerve roots and there have been only ~20 reports of cutaneous or subcutaneous MS to-date in humans. In canines, there have only been two reports of MS, both associated with spinal root nerves. In this report, we describe a 7-year-old Weimaraner cross breed dog that presented with two pigmented lesions on the eyelids. The lesions were surgically removed and histological analysis revealed well-circumscribed, non-encapsulated, expansile, neoplasms that were displacing most of the dermis and adnexa. The first lesion was composed of spindloid cells arranged in short interlacing streams with large amounts of pale eosinophilic cytoplasm that sometimes contained fine melanin granules. In areas there were spindle cells arranged in verocay bodies which led to a diagnosis of MS. In contrast, the second lesion was composed of polygonal cells arranged in thick sheets with large amounts of pale eosinophilic cytoplasm that sometimes contained fine melanin granules. The diagnosis was melanocytoma (which is one of the macroscopic differential diagnoses for MS). Whilst melanocytoma is a commonly occurring cutaneous lesion in canines and surgical removal is considered curative, due to little being known about MS in dogs, the outcome remained guarded, as MS in humans has an unpredictable nature, and recurrence and metastasis have been reported.Wellcomehttps://wellcomeopenresearch.org/hj2024Centre for Veterinary Wildlife StudiesParaclinical SciencesSDG-03:Good heatlh and well-bein

A new approach to the vasectomy of African lions (Panthera leo)

Four healthy, male, adult African lions (Panthera leo) were presented for vasectomy, which was performed for management purposes. After immobilisation with medetomidine and tiletamine/zolazepam the lions were intubated and anaesthesia was maintained with isoflurane. In each animal, the ductus deferens was located bilaterally, dissected and transected. Following ligation, a technique commonly used in human medicine called fascial interposition, was used to decrease the chances of recanalisation. Using this technique, the prostatic end of the ductus was fixated outside the tunica vaginalis, while the testicular end remained within the tunic. Histopathology was performed in all cases to confirm the presence of the ductus deferens tissue. During the follow up, twelve months later, no complications were noticed by the owner and no new litters have been born since.http://www.jsava.co.zaam2024Production Animal StudiesSDG-03:Good heatlh and well-bein