Novel azo-dye quinazolinones as colorimetric chemosensors for detection of cobalt and ferrous ions in aqueous medium

Highly efficient azo-day quinazolinone derivatives carrying a π bond and OH electron donor groups have been designed, synthesized, and evaluated as colorimetric chemosensors for detecting metal ions in biological and environmental samples, which was further supported by the DFT studies and UV–vis titration experiment. The 3-amino-2-styrylquinazolin-4(3H)-one (1) was directed to react with phenols during a diazotization type reaction to form a series of azo-day 3-(diazenyl)-2-(styryl)quinazolin-4(3H)-one (4a-e), which could not only have been confirmed by FTIR, H1NMR, C13NMR, Ms and elemental analysis but could also be easily used for the detection of metal ions. Compound 4c exhibited a rapid qualitative and quantitative method for the detection of CoII at λ max (582 nm) and FeII at λ max (566 nm) in an aqueous solution. The current study introduces a facile, low cost, more specific and selective chemosensor for detecting trace amounts of cobalt and ferrous ions

Synthesis, Structural Determination, and Antioxidant Activities of Acyclic and Substituted Heterocyclic Phosphonates Linearly Linked 4-hydroxy-2(1<i>H</i>)-quinolinone

The chemical reactivity of 3-[(E)-3-(dimethylamino)-2-propenoyl]-4-hydroxy-1-methy-2(1H)-quinolinone (1) towards some phosphorus reagents was studied. The enaminone 1 was cyclized into pyranoquinolinylphosphonate 2 via treatment with diethyl phosphite in basic medium. However, its reaction with triethoxy phosphonoacetate gave the substituted oxopyranylphosphonate 3. Using the same reaction conditions, both thioxopyridinylphosphonate 4 and oxopyranylphosphonate 5 were produced via a reaction of enaminone 1 with both diethyl 2-amino-2-thioxoethylphosphonate and diethyl vinylphosphonate, respectively, in low yields. In addition, the two novel oxopyridinylphosphonates 6 and 7 were obtained by treatment of enaminone 1 with a diethyl cyanomethylphosphonate reagent. Two oaxathiaphosphininyl derivatives, 8 and 9, were obtained by treatment of the enaminone 1 with O, O-diethyl dithiophosphoric acid under different reaction conditions. Diazaphosphininyl 11 and oxazaphosphininyl 12 derivatives were obtained in excellent yields using a P-phenylphosphonic diamide reagent under different reaction conditions. The treatment of the enaminone 1 with phosphorus pentasulfide produced the non-phosphorylated product thioxothiopyranoquinolinone 13. Finally, the enaminone was turned into oxathiaphosphininyl 14 using Lawesson’s reagent. The possible reaction mechanisms of the formation of these products were discussed. The structures of newly isolated products were established by elemental analysis and spectral tools. The compounds were evaluated for their antioxidant activities

Design, synthesis and evaluate of imidazole, triazine and metastable oxazolone derivatives as chemosensor for detecting metals

In the current work, a novel series of substituted imidazole, triazine and metastable Oxazolone derivatives were synthesized. The performance of 4-arylideneoxazol-5(4H)-one (2a-c) towards amoniuma acetate, hydrazine hydrate, phenyhydrazine and primary amines has been discussed. DFT bases and calculations of HUMO, LUMO were used to predict the ability of binding between synthesized compound and cations. All the synthesized compounds were assessed as chemosensors for detection metals ions. Colorimetric investigation confirmed and showed high-selectivity and specificity of compounds 5b and 5c to detect cobalt ion, and copper ion respectively, so compounds 5b and 5c can be directed as a chemosensor for optical detection of Co2+and Cu2+ respectively. On the other hand, new organic chemosensor were established by, IR, 1H NMR, 13C NMR ms spectroscopy and elemental analysis

Enhancement of Antimicrobial and Dyeing Properties of Cellulosic Fabrics via Chitosan Nanoparticles

The primary goal of this study is to prepare chitosan nanoparticles (CSNPs) by the ionic gelation method via the treatment of chitosan (0.2 wt.%) with tripolyphosphate (0.2 wt.%) ultrasonically for 45 min. FT-IR spectroscopy and TEM images were used to characterize and validate CSNP production. Cellulosic materials with different concentrations of CSNPs have better antibacterial and colouring characteristics. The treated cellulosic fabrics were analyzed by FT-IR spectroscopy, SEM, and thermogravimetric analysis. Colourimetric data measurements expressed in K/S values were used to evaluate the impact of CSNPs on the dyeing affinity of cellulosic materials. In addition, antibacterial activity against bacteria and fungi was tested on the treated cellulosic fabrics. According to the K/S values, cellulosic textiles treated with CSNPs (0.3 wt.%) had a better affinity for acid dyeing. These textiles also offer better antibacterial properties and are more resistant to washing, light, and rubbing. A cytotoxicity study found that CSNPs give cellulosic materials antibacterial and acid dyeing properties, which is good for the environment