The Effects of Stress on the Vascular System for Different Ages in Rats

The effects of stress in newborns were more severe than adults, The changes in the blood vessels and the heart of age-related and the result of stress are reflected on adaptation and resistance to the development of cardiovascular disease, such as hypertension. Therefore, experiments were conducted to study the changes developments on the heart and blood vessels under the influence of stress at the stages of maturity, used a laboratory rat model. The impact of each of the chronotropic and the stress on the blood vessels at the newborn rats were higher than adult animals, myocardial indolence and high blood pressure were observed at the old rats compared to adult animals as a result of the stress-responses

An Investigation to the Abrasive Wear in Pipes Used for Oil Industry

The work reported in this study focusing on the abrasive wear behavior for three types of pipes used in oil industries (Carbone steel, Alloy steel and Stainless steel) using a wear apparatus for dry and wet tests, manufactured according to ASTM G65. Silica sand with hardness (1000-1100) HV was used as abrasive material. The abrasive wear of these pipes has been measured experimentally by measuring the wear rate for each case under different sliding speeds, applied loads, and sand conditions (dry or wet). All tests have been conducted using sand of particle size (200-425) µm, ambient temperature of 34.5 °C and humidity 22% (Lab conditions). The results show that the material loss due to abrasive wear increased monotonically with the applied load at constant sliding speed and constant grit size due to increasing depth of penetration in both dry and wet sand which agrees with Archard´s equation. Sliding speed show insignificant effect on the wear loss of metals at constant load and constant grit size in both dry and wet sand. Wet sand results show higher wear losses than dry sand (20-70) % due to micro abrasion – corrosion wear and high slurry concentration

Blood-brain barrier and cerebral blood flow: Age differences in hemorrhagic stroke

Neonatal stroke is similar to the stroke that occurs in adults and produces a significant morbidity and long-term neurologic and cognitive deficits. There are important differences in the factors, clinical events and outcomes associated with the stroke in infants and adults. However, mechanisms underlying age differences in the stroke development remain largely unknown. Therefore, treatment guidelines for neonatal stroke must extrapolate from the adult data that is often not suitable for children. The new information about differences between neonatal and adult stroke is essential for identification of significant areas for future treatment and effective prevention of neonatal stroke. Here, we studied the development of stress-induced hemorrhagic stroke and possible mechanisms underlying these processes in newborn and adult rats. Using histological methods and magnetic resonance imaging, we found age differences in the type of intracranial hemorrhages. Newborn rats demonstrated small superficial bleedings in the cortex while adult rats had more severe deep bleedings in the cerebellum. Using Doppler optical coherent tomography, we found higher stress-reactivity of the sagittal sinus to deleterious effects of stress in newborn vs. adult rats suggesting that the cerebral veins are more vulnerable to negative stress factors in neonatal vs. adult brain in rats. However, adult but not newborn rats demonstrated the stroke-induced breakdown of blood brain barrier (BBB) permeability. The one of possible mechanisms underlying the higher resistance to stress-related stroke injures of cerebral vessels in newborn rats compared with adult animals is the greater expression of two main tight junction proteins of BBB (occludin and claudin-5) in neonatal vs. mature brain in rats