292 research outputs found
Structural coloration in caloenas nicobarica pigeons and refractive index modulated sensing
- Author
- Publication venue
- 'Wiley'
- Publication date
- 28/02/2018
- Field of study
Glucose sensing with phenylboronic acid functionalized hydrogel-based optical diffusers
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- 12/03/2018
- Field of study
Phenylboronic acids have emerged as synthetic receptors that can reversibly bind to cis-diols of glucose molecules. The incorporation of phenylboronic acids in hydrogels offers exclusive attributes; for example, the binding process with glucose induces Donnan osmotic pressure resulting in volumetric changes in the matrix. However, their practical applications are hindered because of complex readout approaches and their time-consuming fabrication processes. Here, we demonstrate a microimprinting method to fabricate densely packed concavities in phenylboronic acid functionalized hydrogel films. A microengineered optical diffuser structure was imprinted on a phenylboronic acid based cis-diol recognizing motif prepositioned in a hydrogel film. The diffuser structure engineered on the hydrogel was based on laser-inscribed arrays of imperfect microlenses that focused the incoming light at different focal lengths and direction resulting in a diffused profile of light in transmission and reflection readout modes. The signature of the dimensional modulation was detected in terms of changing focal lengths of the microlenses due to the volumetric expansion of the hydrogel that altered the diffusion spectra and transmitted beam profile. The transmitted optical light spread and intensity through the sensor was measured to determine variation in glucose concentrations at physiological conditions. The sensor was integrated in a contact lens and placed over an artificial eye. Artificial stimulation of variation in glucose concentration allowed quantitative measurements using a smartphoneâs photodiode. A smartphone app was utilized to convert the received light intensity to quantitative glucose concentration values. The developed sensing platform offers low cost, rapid fabrication, and easy detection scheme as compared to other optical sensing counterparts. The presented detection scheme may have applications in wearable real-time biomarker monitoring devices at point-of-care settings
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990â2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbastabar Hedayat
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdollahi Arash
- Abdullahi Auwal
- Abegaz Kedir Hussein
- AbeldanÌo ZunÌiga Roberto Ariel
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abreu Lucas GuimaraÌes
- Abu-Gharbieh Eman
- Abu-Rmeileh Niveen ME
- Abualruz Hasan
- Ackerman Ilana N
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adebiyi Akindele Olupelumi
- Adepoju Abiola Victor
- Adewuyi Habeeb Omoponle
- Afyouni Shadi
- Afzal Saira
- Afzal Sina
- Agodi Antonella
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Shahzaib
- Ahmed Ali
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ajami Marjan
- Akinosoglou Karolina
- Akkaif Mohammed Ahmed
- Al Hasan Syed Mahfuz
- Al-Aly Ziyad
- Al-Gheethi Adel Ali Saeed
- Al-Marwani Sabah
- Al-Omari Basem
- Al-Wardat Mohammad Sami
- Al-Worafi Yaser Mohammed
- Alalalmeh Samer O
- Albashtawy Mohammed
- Aldridge Robert W
- Alemu Meseret Desalegn
- Alemu Yihun Mulugeta
- Alene Kefyalew Addis
- Alharrasi Maryam
- Alhassan Robert Kaba
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Alif Sheikh Mohammad
- Aljunid Syed Mohamed
- Almazan Joseph Uy
- Alomari Mahmoud A
- Altaany Zaid
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J
- Alwafi Hassan
- Aly Safwat
- Alzoubi Karem H
- Amare Azmeraw T
- Amegbor Prince M
- Ameyaw Edward Kwabena
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Amiri Sohrab
- Amugsi Dickson A
- Ancuceanu Robert
- Anderlini Deanna
- Anderson David B
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Ansari Hossein
- Antony Catherine M
- Anwar Saleha
- Anwar Sumadi Lukman
- Anwer Razique
- Anyanwu Philip Emeka
- Arab Juan Pablo
- Arabloo Jalal
- Arafat Mosab
- Araki Daniel T
- Aravkin Aleksandr Y
- Arkew Mesay
- Armocida Benedetta
- Arndt Michael Benjamin
- Arooj Mahwish
- Artamonov Anton A
- Aruleba Raphael Taiwo
- Arumugam Ashokan
- Ashbaugh Charlie
- Ashemo Mubarek Yesse
- Ashraf Muhammad
- Asika Marvellous O
- Askari Elaheh
- Astell-Burt Thomas
- Athari Seyyed Shamsadin
- Atorkey Prince
- Atout Maha Moh'd Wahbi
- Atreya Alok
- Aujayeb Avinash
- Ausloos Marcel
- Avan Abolfazl
- Awotidebe Adedapo Wasiu
- Awuviry-Newton Kofi
- Ayala Quintanilla Beatriz Paulina
- Ayuso-Mateos Jose L
- Azadnajafabad Sina
- Azevedo Rui M S
- Babu Abraham Samuel
- Badar Muhammad
- Badiye Ashish D
- Baghdadi Soroush
- Bagheri Nasser
- Bah Sulaiman
- Bai Ruhai
- Baker Jennifer L
- Bakkannavar Shankar M
- Bako Abdulaziz T
- Balakrishnan Senthilkumar
- Bam Kiran
- Banik Palash Chandra
- Barchitta Martina
- Bardhan Mainak
- Bardideh Erfan
- Barker-Collo Suzanne Lyn
- Barqawi Hiba Jawdat
- Barrow Amadou
- Barteit Sandra
- Barua Lingkan
- Bashiri Aliabadi Somaye
- Basiru Afisu
- Basu Sanjay
- Basu Saurav
- Bathini Prapthi Persis
- Batra Kavita
- Baune Bernhard T
- Bayileyegn Nebiyou Simegnew
- Behnam Babak
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bejarano Ramirez Diana Fernanda
- Bell Michelle L
- Bello Olorunjuwon Omolaja
- Beloukas Apostolos
- Bensenor Isabela M
- Berezvai Zombor
- Bernabe Eduardo
- Bernstein Robert S
- Bettencourt Paulo J G
- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhandari Dinesh
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Vivek
- Bhatti Gurjit Kaur
- Bhatti Jasvinder Singh
- Bhatti Manpreet S
- Bhatti Rajbir
- Bhutta Zulfiqar A
- Bikbov Boris
- Bishai Jessica Devin
- Bisignano Catherine
- Bitra Veera R
- BjĂžrge Tone
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Bogale Eyob Ketema
- Bonakdar Hashemi Milad
- Bonny Aime
- Bora Basara Berrak
- Borhany Hamed
- Boxe Christopher
- Brady Oliver J
- Bragazzi Nicola Luigi
- Braithwaite Dejana
- Brant Luisa C
- Brauer Michael
- Breitner Susanne
- Brenner Hermann
- Brown Julie
- Brugha Traolach
- Bulamu Norma B
- Buonsenso Danilo
- Burkart Katrin
- Burns Richard A
- Busse Reinhard
- Bustanji Yasser
- Butt Zahid A
- Byun Justin
- Caetano dos Santos Florentino Luciano
- Calina Daniela
- Campos-Nonato Ismael R
- Cao Chao
- Capodici Angelo
- Carr Sinclair
- Carreras Giulia
- Carugno Andrea
- Carvalho MaÌrcia
- Castaldelli-Maia Joao Mauricio
- CastanÌeda-Orjuela Carlos A
- Castelpietra Giulio
- Catapano Alberico L
- Cattaruzza Maria Sofia
- Caye Arthur
- CaÌmera Luis Alberto
- Cegolon Luca
- Cembranel Francieli
- Cenderadewi Muthia
- Cerin Ester
- Chakraborty Promit Ananyo
- Chan Jeffrey Shi Kai
- Chan Raymond N C
- Chandika Rama Mohan
- Chandrasekar Eeshwar K
- Charalampous Periklis
- Chattu Vijay Kumar
- Chatzimavridou-Grigoriadou Victoria
- Chen An-Tian
- Chen Angela W
- Chen Catherine S
- Chen Haowei
- Chen Nathalie M
- Cheng Esther T W
- Chimed-Ochir Odgerel
- Chimoriya Ritesh
- Ching Patrick R
- Cho William C S
- Choi Sungchul
- Chong Bryan
- Chong Yuen Yu
- Choudhari Sonali Gajanan
- Chowdhury Rajiv
- Christensen Steffan Wittrup McPhee
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Chung Eric
- Chung Eunice
- Chutiyami Muhammad
- Claassens Mareli M
- Cogen Rebecca M
- Columbus Alyssa
- Conde Joao
- Cortesi Paolo Angelo
- Cousin Ewerton
- Criqui Michael H
- Cruz-Martins NataÌlia
- D'Oria Mario
- Dadras Omid
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- Damiani Giovanni
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- DaÌvila-Cervantes Claudio Alberto
- De Leo Diego
- Debele Aklilu Tamire
- Debopadhaya Shayom
- DeCleene Nicole K
- Deeba Farah
- Degenhardt Louisa
- Del Bo' Cristian
- Delgado-Enciso Ivan
- Demetriades Andreas K
- Denova-GutieÌrrez Edgar
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- Desai Hardik Dineshbhai
- Desai Rupak
- Deuba Keshab
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- Dhingra Sameer
- Dias da Silva Diana
- Diaz Daniel
- Diaz Luis Antonio
- Diaz Michael J
- Dima Adriana
- Ding Delaney D
- Dirac M Ashworth
- do Prado Camila Bruneli
- Do Thao Huynh Phuong
- Dohare Sushil
- Dominguez Regina-Mae Villanueva
- Dong Wanyue
- Dongarwar Deepa
- Dorsey E Ray
- Doshmangir Leila
- Dowou Robert Kokou
- Driscoll Tim Robert
- Dsouza Haneil Larson
- Dsouza Viola
- Dube John
- Dumith Samuel C
- Duncan Bruce B
- Duraes Andre Rodrigues
- Duraisamy Senbagam
- Durojaiye Oyewole Christopher
- Dzianach Paulina Agnieszka
- Dziedzic Arkadiusz Marian
- Eboreime Ejemai
- Ebrahimi Alireza
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- Edvardsson David
- Eikemo Terje Andreas
- Eini Ebrahim
- Ekholuenetale Michael
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- El Sayed Iman
- El Tantawi Maha
- Elbarazi Iffat
- Elemam Noha Mousaad
- ElGohary Ghada Metwally Tawfik
- Elhadi Muhammed
- Elmeligy Omar Abdelsadek Abdou
- ELNahas Gihan
- Elshaer Mohammed
- Elsohaby Ibrahim
- Engelbert Bain Luchuo
- Erkhembayar Ryenchindorj
- Eshrati Babak
- Estep Kara
- Fabin Natalia
- Fagbamigbe Adeniyi Francis
- Falzone Luca
- Fareed Mohammad
- Farinha Carla Sofia e SaÌ
- Faris MoezAlIslam Ezzat Mahmoud
- Faro Andre
- Farrokhi Pegah
- Fatehizadeh Ali
- Fauk Nelsensius Klau
- Feigin Valery L
- Feng Xiaoqi
- Fereshtehnejad Seyed-Mohammad
- Feroze Abdullah Hamid
- Ferrari Alize J
- Ferreira Nuno
- Ferreira Paulo H
- Fischer Florian
- Flavel Joanne
- Flood David
- Flor Luisa S
- Foigt Nataliya A
- Folayan Morenike Oluwatoyin
- Force Lisa M
- Fortuna Daniela
- Foschi Matteo
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- Freitas Alberto
- Fukumoto Takeshi
- Furtado JoaÌo M
- Gaal Peter Andras
- Gadanya Muktar A
- Gaidhane Abhay Motiramji
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- Galali Yaseen
- Ganbat Mandukhai
- Gandhi Aravind P
- Ganesan Balasankar
- Ganie Mohd Ashraf
- Ganiyani Mohammad Arfat
- Gardner William M
- Gebi Tilaye Gebru
- Gebregergis Miglas W
- Gebrehiwot Mesfin
- Gebremariam Tesfay B B
- Gebremeskel Teferi Gebru
- Gela Yibeltal Yismaw
- Georgescu Simona Roxana
- Getachew Obsa Abera
- Gething Peter W
- Getie Molla
- Ghadiri Keyghobad
- Ghadirian Fataneh
- Ghailan Khalid Yaser
- Ghajar Alireza
- Ghasemi MohammadReza
- Ghasempour Dabaghi Ghazal
- Ghasemzadeh Afsaneh
- Ghazy Ramy Mohamed
- Gholamrezanezhad Ali
- Ghorbani Mahsa
- Ghotbi Elena
- Gibson Ruth Margaret
- Gill Tiffany K
- Ginindza Themba G
- Girmay Alem
- Glasbey James C
- Godinho Myron Anthony
- Goharinezhad Salime
- Goldust Mohamad
- Golechha Mahaveer
- Goleij Pouya
- Gona Philimon N
- Gorini Giuseppe
- Goulart Alessandra C
- GoÌboÌloÌs Laszlo
- Grada Ayman
- Grivna Michal
- Guan Shi-Yang
- Guarducci Giovanni
- Gubari Mohammed Ibrahim Mohialdeen
- Gudeta Mesay Dechasa
- Guha Avirup
- Guicciardi Stefano
- Gulati Snigdha
- Gulisashvili David
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- Guo Cui
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- Gupta Bhawna
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- Gupta Vivek Kumar
- GutieÌrrez Reyna Alma
- Habibzadeh Farrokh
- Habibzadeh Parham
- Haddadi Rasool
- Hadi Najah R
- Haep Nils
- Hafezi-Nejad Nima
- Hafiz Abdul
- Hagins Hailey
- Halboub Esam S
- Halimi Aram
- Haller Sebastian
- Halwani Rabih
- Hamilton Erin B
- Hankey Graeme J
- Hannan Md Abdul
- Haque Md Nuruzzaman
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- Haro Josep Maria
- Hartvigsen Jan
- Hasaballah Ahmed I
- Hasan Ikramul
- Hasanian Mohammad
- Hasnain Md Saquib
- Hassan Amr
- Haubold Johannes
- Havmoeller Rasmus J
- Hay Simon I
- Hayat Khezar
- Hebert Jeffrey J
- Hegazi Omar E
- Heidari Golnaz
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- Hemmati Mehdi
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- Hezam Kamal
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- Hon Julia
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- Hosseinzadeh Hassan
- Hosseinzadeh Mehdi
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- Hostiuc Sorin
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- Huang Junjie
- Hugo Fernando N
- Hushmandi Kiavash
- Hussain Javid
- Hussein Nawfal R
- Huynh Chantal K
- Huynh Hong-Han
- Hwang Bing-Fang
- Iannucci Vincent C
- Ihler Audrey L
- Ikiroma Adalia I
- Ikuta Kevin S
- Ilesanmi Olayinka Stephen
- Ilic Irena M
- Ilic Milena D
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- Isola Gaetano
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- Iwu Chidozie C D
- Iyer Mahalaxmi
- Jaafari Jalil
- Jacobsen Kathryn H
- Jadidi-Niaragh Farhad
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- Jaggi Khushleen
- Jahankhani Kasra
- Jahanmehr Nader
- Jahrami Haitham
- Jain Akhil
- Jain Nityanand
- Jairoun Ammar Abdulrahman
- Jaiswal Abhishek
- Jakovljevic Mihajlo
- Jatau Abubakar Ibrahim
- Javadov Sabzali
- Javaheri Tahereh
- Jayapal Sathish Kumar
- Jayaram Shubha
- Jee Sun Ha
- Jeganathan Jayakumar
- Jeyakumar Angeline
- Jha Anil K
- Jiang Heng
- Jin Yinzi
- Jonas Jost B
- Joo Tamas
- Joseph Abel
- Joseph Nitin
- Joshua Charity Ehimwenma
- Jozwiak Jacek Jerzy
- JuÌrisson Mikk
- K Vaishali
- Kaambwa Billingsley
- Kabir Ali
- Kabir Zubair
- Kadashetti Vidya
- Kalani Rizwan
- Kalankesh Leila R
- Kaliyadan Feroze
- Kalra Sanjay
- Kamenov Kaloyan
- Kamyari Naser
- Kanagasabai Thanigaivelan
- Kandel Himal
- Kanmanthareddy Arun R
- Kanmodi Kehinde Kazeem
- Kantar Rami S
- Karaye Ibraheem M
- Karim Asima
- Karimi Salah Eddin
- Karimi Yeganeh
- Kasraei Hengameh
- Kassel Molly B
- Kauppila Joonas H
- Kawakami Norito
- Kayode Gbenga A
- Kazemi Foad
- Kazemian Sina
- Keikavoosi-Arani Leila
- Keller Cathleen
- Kempen John H
- Kerr Jessica A
- Keshtkar Kamyab
- Kesse-Guyot Emmanuelle
- Keykhaei Mohammad
- Khajuria Himanshu
- Khalaji Amirmohammad
- Khalid Asaad
- Khalid Nauman
- Khalilian Alireza
- Khamesipour Faham
- Khan Asaduzzaman
- Khan Ikramullah
- Khan Maseer
- Khan Moien AB
- Khanmohammadi Shaghayegh
- Khatab Khaled
- Khatami Fatemeh
- Khatatbeh Moawiah Mohammad
- Khater Amir M
- Khayat Kashani Hamid Reza
- Khidri Feriha Fatima
- Khodadoust Elaheh
- Khormali Moein
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- Kim Min Seo
- Kimokoti Ruth W
- Kisa Adnan
- Kisa Sezer
- Knudsen Ann Kristin Skrindo
- Kocarnik Jonathan M
- Kochhar Sonali
- Koh Hyun Yong
- Kolahi Ali-Asghar
- Kompani Farzad
- Koren Gerbrand
- Korzh Oleksii
- Kosen Soewarta
- Koulmane Laxminarayana Sindhura Lakshmi
- Krishan Kewal
- Krishna Varun
- Krishnamoorthy Vijay
- Kuate Defo Barthelemy
- Kuddus Md Abdul
- Kuddus Mohammed
- Kuitunen Ilari
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- Kumar Manasi
- Kumar Nithin
- Kumar Rakesh
- Kurmi Om P
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- Larijani Bagher
- Larsson Anders O
- Lasrado Savita
- Lauriola Paolo
- LaÌm Judit
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- Leasher Janet L
- Ledda Caterina
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- Lee Paul H
- Lee Sang-woong
- Lee Seung Won
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- Lenzi Jacopo
- Leong Elvynna
- Leung Janni
- Li Ming-Chieh
- Li Wei
- Li Xiaopan
- Li Yichong
- Li Yongze
- Lim Lee-Ling
- Lim Stephen S
- Lindstrom Megan
- Linn Shai
- Liu Gang
- Liu Runben
- Liu Shiwei
- Liu Wei
- Liu Xiaofeng
- Liu Xuefeng
- Llanaj Erand
- Lo Chun-Han
- Loreche Arianna Maever
- Lorenzovici LaÌszloÌ
- Lozano Rafael
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- Lubinda Jailos
- Lucchetti Giancarlo
- Lunevicius Raimundas
- Lusk Jay B
- lv hengliang
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- Madureira-Carvalho AÌurea M
- MaganÌa GoÌmez Javier A
- Maghazachi Azzam A
- Maharjan Preeti
- Mahasha Phetole Walter
- Maheri Mina
- Mahjoub Soleiman
- Mahmoud Mansour Adam
- Mahmoudi Elham
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- Malik Iram
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- Manla Yosef
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- Mansouri Pejman
- Mansournia Mohammad Ali
- Mantilla Herrera Ana M
- Mantovani Lorenzo Giovanni
- Manu Emmanuel
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- Martinez-Piedra Ramon
- Martini Daniela
- Martins-Melo Francisco RogerlaÌndio
- Martorell Miquel
- Marx Wolfgang
- Maryam Sharmeen
- Marzo Roy Rillera
- Mathangasinghe Yasith
- Mathieson Stephanie
- Mathioudakis Alexander G
- Mattumpuram Jishanth
- Maugeri Andrea
- Mayeli Mahsa
- Mazidi Mohsen
- Mazzotti Antonio
- McGrath John J
- McKee Martin
- McKowen Anna Laura W
- McPhail Michael A
- Mehrabani-Zeinabad Kamran
- Mehrabi Nasab Entezar
- Mekene Meto Tesfahun
- Mendoza Walter
- Menezes Ritesh G
- Mensah George A
- Mentis Alexios-Fotios A
- Meo Sultan Ayoub
- Meresa Haftu Asmerom
- Meretoja Atte
- Meretoja Tuomo J
- Mersha Abera M
- Mestrovic Tomislav
- Mettananda Kukulege Chamila Dinushi
- Mettananda Sachith
- Michalek Irmina Maria
- Miller Paul Anthony
- Miller Ted R
- Mills Edward J
- Minh Le Huu Nhat
- Mirijello Antonio
- Mirrakhimov Erkin M
- Mirutse Mizan Kiros
- Mirza-Aghazadeh-Attari Mohammad
- Mirzaei Maryam
- Mirzaei Roya
- Misganaw Awoke
- Mishra Ajay Kumar
- Mitchell Philip B
- Mittal Chaitanya
- Moazen Babak
- Moberg Madeline E
- Mohamed Jama
- Mohamed Mouhand F H
- Mohamed Nouh Saad
- Mohammadi Esmaeil
- Mohammadi Soheil
- Mohammed Hussen
- Mohammed Salahuddin
- Mohammed Shafiu
- Mohr Robin M
- Mokdad Ali H
- Molinaro Sabrina
- Momtazmanesh Sara
- Monasta Lorenzo
- Mondello Stefania
- Moodi Ghalibaf AmirAli
- Moradi Maryam
- Moradi Yousef
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- Moraga Paula
- Morawska Lidia
- Moreira Rafael Silveira
- Morovatdar Negar
- Morrison Shane Douglas
- Morze Jakub
- Mosapour Abbas
- Mosser Jonathan F
- Mossialos Elias
- Motappa Rohith
- Mougin Vincent
- Mouodi Simin
- Mrejen MatiÌas
- Msherghi Ahmed
- Mubarik Sumaira
- Mueller Ulrich Otto
- Mulita Francesk
- Munjal Kavita
- Murillo-Zamora EfreÌn
- Murlimanju BV
- Murray Christopher J L
- Mustafa Ghulam
- Muthu Sathish
- Muzaffar Muhammad
- Myung Woojae
- Nagarajan Ahamarshan Jayaraman
- Naghavi Pirouz
- Naik Ganesh R
- Nainu Firzan
- Nair Sanjeev
- Najmuldeen Hastyar Hama Rashid
- Nangia Vinay
- Naqvi Atta Abbas
- Narayana Aparna Ichalangod
- Nargus Shumaila
- Nascimento Gustavo G
- Nashwan Abdulqadir J
- Nasrollahizadeh Ali
- Nasrollahizadeh Amir
- Natto Zuhair S
- Nayak Biswa Prakash
- Nayak Vinod C
- Nduaguba Sabina Onyinye
- Negash Hadush
- Negoi Ionut
- Negoi Ruxandra Irina
- Nejadghaderi Seyed Aria
- Nesbit Olivia D
- Netsere Henok Biresaw
- Ng Marie
- Nguefack-Tsague Georges
- Ngunjiri Josephine W
- Nguyen Dang H
- Nguyen Hien Quang
- Niazi Robina Khan
- Nikolouzakis Taxiarchis Konstantinos
- Nikoobar Ali
- Nikoomanesh Fatemeh
- Nikpoor Amin Reza
- Nnaji Chukwudi A
- Nnyanzi Lawrence Achilles
- Noman Efaq Ali
- Nomura Shuhei
- Norrving Bo
- Nri-Ezedi Chisom Adaobi
- Ntaios George
- Ntsekhe Mpiko
- Nurrika Dieta
- Nzoputam Chimezie Igwegbe
- Nzoputam Ogochukwu Janet
- O'Donnell Martin James
- Oancea Bogdan
- Odetokun Ismail A
- Oguntade Ayodipupo Sikiru
- Oguta James Odhiambo
- Okati-Aliabad Hassan
- Okeke Sylvester Reuben
- Okekunle Akinkunmi Paul
- Okonji Osaretin Christabel
- Olagunju Andrew T
- Olasupo Omotola O
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- Xia Yanjie
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- Xu Yvonne Yiru
- Yadav Lalit
- Yadollahpour Ali
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- Yao Yao
- Yaribeygi Habib
- Yazdanpanah Mohammad Hosein
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- Yehualashet Sisay Shewasinad
- Yesuf Subah Abderehim
- Yezli Saber
- Yigzaw Zeamanuel Anteneh
- YigÌit Arzu
- YigÌit Vahit
- Yismaw Yazachew
- Yon Dong Keon
- Yonemoto Naohiro
- Younis Mustafa Z
- Yu Chuanhua
- Yu Yong
- Yusuf Hadiza
- Zahid Mondal Hasan
- Zakham Fathiah
- Zaki Leila
- Zaki Nazar
- Zaman Burhan Abdullah
- Zamora Nelson
- Zand Ramin
- Zandieh Ghazal G Z
- Zar Heather J
- Zarrintan Armin
- Zastrozhin Mikhail Sergeevich
- Zhang Haijun
- Zhang Ning
- Zhang Yunquan
- Zhao Hanqing
- Zhong Chenwen
- Zhong Panliang
- Zhou Juexiao
- Zhu Zhaohua
- Ziafati Makan
- ZielinÌska Magdalena
- Zimsen Stephanie R M
- Zoladl Mohammad
- Zumla Alimuddin
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. For three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has filled that need. A global network of collaborators contributed to the production of GBD 2021 by providing, reviewing, and analysing all available data. GBD estimates are updated routinely with additional data and refined analytical methods. GBD 2021 presents, for the first time, estimates of health loss due to the COVID-19 pandemic. Methods: The GBD 2021 disease and injury burden analysis estimated years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries using 100 983 data sources. Data were extracted from vital registration systems, verbal autopsies, censuses, household surveys, disease-specific registries, health service contact data, and other sources. YLDs were calculated by multiplying cause-age-sex-location-year-specific prevalence of sequelae by their respective disability weights, for each disease and injury. YLLs were calculated by multiplying cause-age-sex-location-year-specific deaths by the standard life expectancy at the age that death occurred. DALYs were calculated by summing YLDs and YLLs. HALE estimates were produced using YLDs per capita and age-specific mortality rates by location, age, sex, year, and cause. 95% uncertainty intervals (UIs) were generated for all final estimates as the 2·5th and 97·5th percentiles values of 500 draws. Uncertainty was propagated at each step of the estimation process. Counts and age-standardised rates were calculated globally, for seven super-regions, 21 regions, 204 countries and territories (including 21 countries with subnational locations), and 811 subnational locations, from 1990 to 2021. Here we report data for 2010 to 2021 to highlight trends in disease burden over the past decade and through the first 2 years of the COVID-19 pandemic. Findings: Global DALYs increased from 2·63 billion (95% UI 2·44â2·85) in 2010 to 2·88 billion (2·64â3·15) in 2021 for all causes combined. Much of this increase in the number of DALYs was due to population growth and ageing, as indicated by a decrease in global age-standardised all-cause DALY rates of 14·2% (95% UI 10·7â17·3) between 2010 and 2019. Notably, however, this decrease in rates reversed during the first 2 years of the COVID-19 pandemic, with increases in global age-standardised all-cause DALY rates since 2019 of 4·1% (1·8â6·3) in 2020 and 7·2% (4·7â10·0) in 2021. In 2021, COVID-19 was the leading cause of DALYs globally (212·0 million [198·0â234·5] DALYs), followed by ischaemic heart disease (188·3 million [176·7â198·3]), neonatal disorders (186·3 million [162·3â214·9]), and stroke (160·4 million [148·0â171·7]). However, notable health gains were seen among other leading communicable, maternal, neonatal, and nutritional (CMNN) diseases. Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3â51·7) and for diarrhoeal diseases decreased by 47·0% (39·9â52·9). Non-communicable diseases contributed 1·73 billion (95% UI 1·54â1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5â9·5). Between 2010 and 2021, among the 25 leading Level 3 causes, age-standardised DALY rates increased most substantially for anxiety disorders (16·7% [14·0â19·8]), depressive disorders (16·4% [11·9â21·3]), and diabetes (14·0% [10·0â17·4]). Age-standardised DALY rates due to injuries decreased globally by 24·0% (20·7â27·2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61·3 years (58·6â63·6) in 2010 to 62·2 years (59·4â64·7) in 2021. However, despite this overall increase, HALE decreased by 2·2% (1·6â2·9) between 2019 and 2021. Interpretation: Putting the COVID-19 pandemic in the context of a mutually exclusive and collectively exhaustive list of causes of health loss is crucial to understanding its impact and ensuring that health funding and policy address needs at both local and global levels through cost-effective and evidence-based interventions. A global epidemiological transition remains underway. Our findings suggest that prioritising non-communicable disease prevention and treatment policies, as well as strengthening health systems, continues to be crucially important. The progress on reducing the burden of CMNN diseases must not stall; although global trends are improving, the burden of CMNN diseases remains unacceptably high. Evidence-based interventions will help save the lives of young children and mothers and improve the overall health and economic conditions of societies across the world. Governments and multilateral organisations should prioritise pandemic preparedness planning alongside efforts to reduce the burden of diseases and injuries that will strain resources in the coming decades. Funding: Bill & Melinda Gates Foundation
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990â2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Abate Kalkidan Hassen
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasi Madineh Akram
- Abbasi-Kangevari Mohsen
- Abbasian Mohammadreza
- Abbasifard Mitra
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdi Parsa
- Abdollahi Mohammad
- Abdoun Meriem
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abebe Mesfin
- Abedi Aidin
- Abedi Armita
- Abegaz Tadesse M
- AbeldanÌo ZunÌiga Roberto Ariel
- Abiodun Olumide
- Abiso Temesgen Lera
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas GuimaraÌes
- Abu-Gharbieh Eman
- Abu-Zaid Ahmed
- Abualruz Hasan
- Abubakar Bilyaminu
- Abukhadijah Hana Jihad Jihad
- Aburuz Salahdein
- Adane Mesafint Molla
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adedoyin Rufus Adesoji
- Adekanmbi Victor
- Aden Bashir
- Adetunji Juliana Bunmi
- Adeyeoluwa Temitayo Esther
- Adha Rishan
- Adibi Amin
- Adnani Qorinah Estiningtyas Sakilah
- Adzigbli Leticia Akua
- Afolabi Aanuoluwapo Adeyimika
- Afolabi Rotimi Felix
- Afshin Ashkan
- Afyouni Shadi
- Afzal Muhammad Sohail
- Afzal Saira
- Agampodi Suneth Buddhika
- Agbozo Faith
- Aghamiri Shahin
- Agodi Antonella
- Agrawal Anurag
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Noah
- Ahmad Shahzaib
- Ahmad Tauseef
- Ahmed Ali
- Ahmed Anisuddin
- Ahmed Ayman
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Safoora
- Ahmed Syed Anees
- Ajami Marjan
- Akalu Gizachew Taddesse
- Akara Essona Matatom
- Akbarialiabad Hossein
- Akhlaghi Shiva
- Akinosoglou Karolina
- Akinyemiju Tomi
- Akkaif Mohammed Ahmed
- Akkala Sreelatha
- Akombi-Inyang Blessing
- Al Awaidy Salah
- Al Hasan Syed Mahfuz
- AL-Ahdal Tareq Mohammed Ali
- Al-Aly Ziyad
- Al-Fatly Bassam
- Al-Gheethi Adel Ali Saeed
- Al-Habbal Khairat
- Al-Marwani Sabah
- Al-Mekhlafi Hesham M
- Al-Raddadi Rajaa M
- Al-Rifai Rami Hani
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Wardat Mohammad Sami
- Al-Worafi Yaser Mohammed
- Al-Zyoud Walid
- Alahdab Fares
- Alalalmeh Samer O
- Alalwan Tariq A
- Alam Khurshid
- Alam Nazmul
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albakri Almaza
- AlBataineh Mohammad T
- Aldhaleei Wafa A
- Aldridge Robert W
- Alemayohu Mulubirhan Assefa
- Alemu Yihun Mulugeta
- Alhabib Khalid F
- Alhassan Robert Kaba
- Ali Abid
- Ali Amjad
- Ali Beriwan Abdulqadir
- Ali Iman
- Ali Liaqat
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Ali Waad
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Aljunid Syed Mohamed
- Alla François
- Almustanyir Sami
- Alomari Mahmoud A
- Alonso Jordi
- Alqahtani Jaber S
- Alqutaibi Ahmed Yaseen
- Alrawashdeh Ahmad
- Alrousan Sahel Majed
- Alshahrani Najim Z
- Altaany Zaid
- Altaf Awais
- Altirkawi Khalid A
- Aluh Deborah Oyine
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J
- Alwafi Hassan
- Aly Hany
- Aly Safwat
- Alzoubi Karem H
- Amaechi Uchenna Anderson
- Aman Mohammadi Masous
- Amani Reza
- Amiri Sohrab
- Amirzade-Iranaq Mohammad Hosein
- Ammirati Enrico
- Amu Hubert
- Amugsi Dickson A
- Amusa Ganiyu Adeniyi
- Ancuceanu Robert
- Anderlini Deanna
- Anderson Jason A
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Andrei Tudorel
- Anenberg Susan C
- Angappan Dhanalakshmi
- Angus Colin
- Anil Abhishek
- Anil Sneha
- Anjum Afifa
- Anoushiravani Amir
- Antonazzo Ippazio Cosimo
- Antony Catherine M
- Antriyandarti Ernoiz
- Anuoluwa Boluwatife Stephen
- Anvari Davood
- Anvari Saeid
- Anwar Saleha
- Anwar Sumadi Lukman
- Anwer Razique
- Anyabolo Ekenedilichukwu Emmanuel
- Anyasodor Anayochukwu Edward
- Apostol Geminn Louis Carace
- Arabloo Jalal
- Arabzadeh Bahri Razman
- Arafat Mosab
- Aravkin Aleksandr Y
- Areda Demelash
- Aregawi Brhane Berhe
- Aremu Abdulfatai
- Armocida Benedetta
- Arndt Michael Benjamin
- Arooj Mahwish
- Artamonov Anton A
- Artanti Kurnia Dwi
- Aruleba Idowu Thomas
- Arumugam Ashokan
- Asbeutah Akram M
- Asgary Saeed
- Asgedom Akeza Awealom
- Ashbaugh Charlie
- Ashemo Mubarek Yesse
- Ashraf Tahira
- Askarinejad Amir
- Assmus Michael
- Astell-Burt Thomas
- Athar Mohammad
- Athari Seyyed Shamsadin
- Atorkey Prince
- Atreya Alok
- Aujayeb Avinash
- Ausloos Marcel
- Avila-Burgos Leticia
- Awoke Andargie Abate
- Ayala Quintanilla Beatriz Paulina
- Ayatollahi Haleh
- Ayestas Portugal Carlos
- Ayuso-Mateos Jose L
- Azadnajafabad Sina
- Azevedo Rui M S
- Azhar Gulrez Shah
- Azizi Hosein
- Azzam Ahmed Y
- AÌrnloÌv Johan
- Backhaus Insa Linnea
- Badar Muhammad
- Badiye Ashish D
- Bagga Arvind
- Baghdadi Soroush
- Bagheri Nasser
- Bagherieh Sara
- Bahrami Taghanaki Pegah
- Bai Ruhai
- Baig Atif Amin
- Baker Jennifer L
- Bakkannavar Shankar M
- Balasubramanian Madhan
- Baltatu Ovidiu Constantin
- Bam Kiran
- Bandyopadhyay Soham
- Banik Biswajit
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- Bansal Hansi
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- Bardhan Mainak
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- Barqawi Hiba Jawdat
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- Barrow Amadou
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- Batchu Sai
- Batra Kavita
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- Bayati Mohsen
- Bayileyegn Nebiyou Simegnew
- BaÌrnighausen Till Winfried
- Beaney Thomas
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bekele Alehegn
- Belgaumi Uzma Iqbal
- Bell Arielle Wilder
- Bell Michelle L
- Bello Muhammad Bashir
- Bello Olorunjuwon Omolaja
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- Yu Yong
- Zadey Siddhesh
- Zadnik Vesna
- Zakham Fathiah
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- Zakzuk Josefina
- Zamagni Giulia
- Zaman Sojib Bin
- Zandieh Ghazal G Z
- ZanghiÌ Aurora
- Zar Heather J
- Zare Iman
- Zarimeidani Fatemeh
- Zastrozhin Mikhail Sergeevich
- Zeng Youjie
- Zhai Chunxia
- Zhang Anthony Lin
- Zhang Haijun
- Zhang Liqun
- Zhang Meixin
- Zhang Yunquan
- Zhang Zhenyu
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhao Jeff T
- Zhao Xiu-Ju George
- Zhao Yang
- Zhao Yong
- Zheng Peng
- Zhong Chenwen
- Zhou Jingjing
- Zhou Juexiao
- Zhou Shangcheng
- Zhu Bin
- Zhu Lei
- Zhu Zhaohua
- Ziaeian Boback
- Ziafati Makan
- ZielinÌska Magdalena
- Zimsen Stephanie R M
- Zoghi Ghazal
- Zoller Thomas
- Zumla Alimuddin
- Zyoud Sa'ed H
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 risk factors in 204 countries and territories and 811 subnational locations, from 1990 to 2021. Methods: The GBD 2021 risk factor analysis used data from 54 561 total distinct sources to produce epidemiological estimates for 88 risk factors and their associated health outcomes for a total of 631 riskâoutcome pairs. Pairs were included on the basis of data-driven determination of a riskâoutcome association. Age-sex-location-year-specific estimates were generated at global, regional, and national levels. Our approach followed the comparative risk assessment framework predicated on a causal web of hierarchically organised, potentially combinative, modifiable risks. Relative risks (RRs) of a given outcome occurring as a function of risk factor exposure were estimated separately for each riskâoutcome pair, and summary exposure values (SEVs), representing risk-weighted exposure prevalence, and theoretical minimum risk exposure levels (TMRELs) were estimated for each risk factor. These estimates were used to calculate the population attributable fraction (PAF; ie, the proportional change in health risk that would occur if exposure to a risk factor were reduced to the TMREL). The product of PAFs and disease burden associated with a given outcome, measured in disability-adjusted life-years (DALYs), yielded measures of attributable burden (ie, the proportion of total disease burden attributable to a particular risk factor or combination of risk factors). Adjustments for mediation were applied to account for relationships involving risk factors that act indirectly on outcomes via intermediate risks. Attributable burden estimates were stratified by Socio-demographic Index (SDI) quintile and presented as counts, age-standardised rates, and rankings. To complement estimates of RR and attributable burden, newly developed burden of proof risk function (BPRF) methods were applied to yield supplementary, conservative interpretations of riskâoutcome associations based on the consistency of underlying evidence, accounting for unexplained heterogeneity between input data from different studies. Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. Findings: Among the specific risk factors analysed for this study, particulate matter air pollution was the leading contributor to the global disease burden in 2021, contributing 8·0% (95% UI 6·7â9·4) of total DALYs, followed by high systolic blood pressure (SBP; 7·8% [6·4â9·2]), smoking (5·7% [4·7â6·8]), low birthweight and short gestation (5·6% [4·8â6·3]), and high fasting plasma glucose (FPG; 5·4% [4·8â6·0]). For younger demographics (ie, those aged 0â4 years and 5â14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9â27·7]) and environmental and occupational risks (decrease of 22·0% [15·5â28·8]), coupled with a 49·4% (42·3â56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. Age-standardised global DALY rates attributable to high BMI and high FPG rose considerably (15·7% [9·9â21·7] for high BMI and 7·9% [3·3â12·9] for high FPG) over this period, with exposure to these risks increasing annually at rates of 1·8% (1·6â1·9) for high BMI and 1·3% (1·1â1·5) for high FPG. By contrast, the global risk-attributable burden and exposure to many other risk factors declined, notably for risks such as child growth failure and unsafe water source, with age-standardised attributable DALYs decreasing by 71·5% (64·4â78·8) for child growth failure and 66·3% (60·2â72·0) for unsafe water source. We separated risk factors into three groups according to trajectory over time: those with a decreasing attributable burden, due largely to declining risk exposure (eg, diet high in trans-fat and household air pollution) but also to proportionally smaller child and youth populations (eg, child and maternal malnutrition); those for which the burden increased moderately in spite of declining risk exposure, due largely to population ageing (eg, smoking); and those for which the burden increased considerably due to both increasing risk exposure and population ageing (eg, ambient particulate matter air pollution, high BMI, high FPG, and high SBP). Interpretation: Substantial progress has been made in reducing the global disease burden attributable to a range of risk factors, particularly those related to maternal and child health, WaSH, and household air pollution. Maintaining efforts to minimise the impact of these risk factors, especially in low SDI locations, is necessary to sustain progress. Successes in moderating the smoking-related burden by reducing risk exposure highlight the need to advance policies that reduce exposure to other leading risk factors such as ambient particulate matter air pollution and high SBP. Troubling increases in high FPG, high BMI, and other risk factors related to obesity and metabolic syndrome indicate an urgent need to identify and implement interventions
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950â2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abbafati Cristiana
- Abbas Jaffar
- Abbasgholizadeh Rouzbeh
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdoun Meriem
- Abdullahi Auwal
- Abdurehman Ame Mehadi
- Abebe Mesfin
- Abedi Aidin
- Abedi Armita
- Abegaz Tadesse M
- AbeldanÌo ZunÌiga Roberto Ariel
- Abhilash E S
- Abiodun Olugbenga Olusola
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abouzid Mohamed
- Abreu Lucas GuimaraÌes
- Abrha Woldu Aberhe
- Abrigo Michael R M
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Aburuz Salahdein
- Acuna Juan Manuel
- Adair Tim
- Addo Isaac Yeboah
- Adebayo Oladimeji M
- Adegboye Oyelola A
- Adekanmbi Victor
- Aden Bashir
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adeyeoluwa Temitayo Esther
- Adeyomoye Olorunsola Israel
- Adha Rishan
- Adibi Amin
- Adikusuma Wirawan
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afework Abel
- Afolabi Aanuoluwapo Adeyimika
- Afraz Ali
- Afyouni Shadi
- Afzal Saira
- Agasthi Pradyumna
- Aghamiri Shahin
- Agodi Antonella
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
- Ahmadzade Mohadese
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Ajumobi Olufemi
- Akalu Gizachew Taddesse
- Akara Essona Matatom
- Akinosoglou Karolina
- Akkala Sreelatha
- Akyirem Samuel
- Al Hamad Hanadi
- Al Hasan Syed Mahfuz
- Al Homsi Ammar
- Al Qadire Mohammad
- AL-Ahdal Tareq Mohammed Ali
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Eyadhy Ayman
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Jumaily Adel
- Al-Marwani Sabah
- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Ala Moein
- Aladelusi Timothy Olukunle
- Alalalmeh Samer O
- Alam Khurshid
- Alam Manjurul
- Alam Zufishan
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Aldridge Robert W
- Alemi Sharifullah
- Alhabib Khalid F
- Alhalaiqa Fadwa Alhalaiqa Naji
- Ali Abid
- Ali Akhtar
- Ali Beriwan Abdulqadir
- Ali Hassam
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Ali Zahid
- Alian Samakkhah Shohreh
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Aligol Mohammad
- Alimi Rasoul
- Aliyi Ahmednur Adem
- Aljunid Syed Mohamed
- Almahmeed Wael
- Almazan Joseph Uy
- Almidani Omar
- Alomari Mahmoud A
- Alonso Nivaldo
- Alqahtani Jaber S
- Alqutaibi Ahmed Yaseen
- Altaf Awais
- Altirkawi Khalid A
- Alvi Farrukh Jawad
- Alwafi Hassan
- Aly Hany
- Alzoubi Karem H
- Amare Azmeraw T
- Ameyaw Edward Kwabena
- Amhare Abebe Feyissa
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Aminian Dehkordi Javad
- Amiri Sohrab
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- Yesera Gesila Endashaw
- Yesodharan Renjulal
- Yesuf Subah Abderehim
- YigÌit Arzu
- YigÌit Vahit
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- Yon Dong Keon
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa Z
- Yu Chuanhua
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zahedi Mohammad
- Zahid Muhammad Nauman
- Zahir Mazyar
- Zakham Fathiah
- Zaki Nazar
- Zakzuk Josefina
- Zamagni Giulia
- Zaman Burhan Abdullah
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
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- ZanghiÌ Aurora
- Zare Iman
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed G M
- Zeng Youjie
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Hongwei
- Zhang Yunquan
- Zhang Zhaofeng
- Zhang Zhenyu
- Zhao Hanqing
- Zhao Yang
- Zhao Yong
- Zheng Peng
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Zhaohua
- Ziaeefar Pardis
- ZielinÌska Magdalena
- Zou Zhiyong
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020â21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5â65·1] decline), and increased during the COVID-19 pandemic period (2020â21; 5·1% [0·9â9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98â5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50â6·01) in 2019. An estimated 131 million (126â137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7â17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8â24·8), from 49·0 years (46·7â51·3) to 71·7 years (70·9â72·5). Global life expectancy at birth declined by 1·6 years (1·0â2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67â8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4â52·7]) and south Asia (26·3% [9·0â44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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- Reynolds IS
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- Riddell A
- Ridgway PF
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- Ronellenfitsch U
- Rosa F
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- Roslani April C
- Rosseau Gail
- Rossi S
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- Ruivo A
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- Russo IS
- Rutegard Martin
- Ruzzenente A
- Ryan EJ
- Ryan M
- Saad MM
- Sabry A
- Sagnotta A
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- Saksena AR
- Salama Abdelkader
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- Salindera S
- Sallam I
- Samadov E
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- Santos Irene
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- Schineis C
- Schizas D
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- Scotton G
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- Seguin-givelet A
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- Shaw Richard
- Shehata S
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- Sherif Ahmed Elshawadfy
- Sherif G
- Shokuhi P
- Sholadoye TT
- Shu Sebastian
- Shylasree TS
- Siaw-Acheampong Kwabena
- Sibilla MG
- Siddiqui MT
- Sidek Mohamed AS
- Sidiropoulos T
- Silva A
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- Simoes Joana FF
- Singh Jagdeep K
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- Subhi MT
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- Subramaniam S
- Sund Malin
- Sundar Sudha
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- Sutherland A
- Swinson B
- Syed WAS
- Syllaios A
- Szubota I
- Tabiri Stephen
- Tactuk N
- Taddei A
- Taibi A
- Talaat M
- Tamini N
- Tammaro P
- Tan JA
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- Tartaglia D
- Tasis N
- Tavares F
- Tawheed A
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- Teixeira M
- Testa V
- Thanapal MR
- Thekinkattil Dinesh
- Theodosopoulos T
- Thian A
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- Tirotta Fabio
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- Tom K
- Tonini V
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- Townen Philip
- Townend D
- Townend Philip
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- Tropeano FP
- Tsiaoussis I
- Tsoulfas G
- Tsoulfas Georgios
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- Tufo A
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- Turri G
- Tzedakis S
- Tzovaras G
- Ugolini G
- Umair M
- Umar A
- Urbani A
- Usai A
- Uzunoglu FG
- Vaccarella G
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- Valenzuela J
- Vallance Abigail
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- van der Plas Willemijn
- Van Heinsbergen M
- Van Nieuwenhove Y
- Van Ramshorst G
- van Ramshorst Gabrielle H
- Varghese Chris
- Vasey C
- Vassiliu P
- Vaz S
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- Veetil Kannummal S
- Vendrame C
- Venskutonis D
- Vergari R
- Vernon L
- Vescio G
- Vezakis A
- Vidya Raghavan
- Vieira A
- Vieira B
- Vignali A
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- Vimalachandran Dale
- Vimalchandra Dale
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- Wedderburn Duane
- Weitz J
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- Whelan M
- Wilkins Alex
- Willaert W
- Wimmer A
- Winter D
- Winter Stuart C
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- Wood M
- Wrigh Naomi
- Wullschleger M
- Xavier R
- Xenaki S
- Xynos E
- Yadev I
- Yang W
- Ye G
- Yezzaji H
- Yiallourou A
- Yousof EA
- Yunus Mohd MF
- Yurttas C
- Zakaria AD
- Zakaria Z
- Zambon M
- Zanus G
- Zatecky J
- Zelic M
- Zerbib P
- Zervas K
- Zese M
- Zhang H
- Zizzo M
- Zmora O
- Zografos C
- Zonta S
- Zourntou S
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/06/2022
- Field of study
AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4âweeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4âweeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, PÂ =Â 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, Pâ<â0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, PÂ =Â 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, PÂ =Â 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC
- Author
- Acharya Shreyasi
- Adamova Dagmar
- Adolfsson Jonatan
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Al-turany Mohammad
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alfaro Molina Jose Ruben
- Ali Yasir
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altenkamper Lucas
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andreou Dimitra
- Andrews Harry Arthur
- Andronic Anton
- Anguelov Venelin
- Anson Christopher Daniel
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Ball Markus
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barioglio Luca
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartsch Esther
- Bashir Butt Jamila
- Bastid Nicole
- Basu Sumit
- Batigne Guillaume
- Batyunya Boris
- Batzing Paul Christoph
- Bautista Guzman Irais
- Bazo Alba Jose Luis
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
- Bertens Redmer Alexander
- Berzano Dario
- Betev Latchezar
- Bhasin Anju
- Bhat Inayat Rasool
- Bhattacharjee Buddhadeb
- Bhom Jihyun
- Bianchi Antonio
- Bianchi Livio
- Bianchi Nicola
- Bianchin Chiara
- Bielcik Jaroslav
- Bielcikova Jana
- Bilandzic Ante
- Biro Gabor
- Biswas Rathijit
- Biswas Saikat
- Blair Justin Thomas
- Blau Dmitry
- Blume Christoph
- Boca Gianluigi
- Bock Friederike
- Bogdanov Alexey
- Boldizsar Laszlo
- Bombara Marek
- Bonomi Germano
- Bonora Matthias
- Book Julian Heinz
- Borel Herve
- Borissov Alexander
- Borri Marcello
- Botta Elena
- Bourjau Christian
- Bratrud Lars
- Braun-munzinger Peter
- Bregant Marco
- Broker Theo Alexander
- Broz Michal
- Brucken Erik Jens
- Bruna Elena
- Bruno Giuseppe Eugenio
- Budnikov Dmitry
- Buesching Henner
- Bufalino Stefania
- Buhler Paul
- Buncic Predrag
- Busch Oliver
- Buthelezi Edith Zinhle
- Buxton Jesse Thomas
- Cabala Jan
- Cabanillas Noris Juan Carlos
- Caffarri Davide
- Caines Helen Louise
- Caliva Alberto
- Calvo Villar Ernesto
- Camerini Paolo
- Capon Aaron Allan
- Carena Francesco
- Carena Wisla
- Carnesecchi Francesca
- Castillo Castellanos Javier Ernesto
- Castro Andrew John
- Casula Ester Anna Rita
- Ceballos Sanchez Cesar
- Chandra Sinjini
- Chang Beomsu
- Chang Wan
- Chapeland Sylvain
- Chartier Marielle
- Chattopadhyay Subhasis
- Chattopadhyay Sukalyan
- Chauvin Alex
- Cheshkov Cvetan Valeriev
- Cheynis Brigitte
- Chibante Barroso Vasco Miguel
- Cho Soyeon
- Chochula Peter
- Chojnacki Marek
- Choudhury Subikash
- Chowdhury Tasnuva
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter
- Chujo Tatsuya
- Chung Suh-urk
- Chunhui Zhang
- Cicalo Corrado
- Cifarelli Luisa
- Cindolo Federico
- Cleymans Jean Willy Andre
- Colamaria Fabio Filippo
- Colella Domenico
- Collu Alberto
- Colocci Manuel
- Concas Matteo
- Conesa Balbastre Gustavo
- Conesa Del Valle Zaida
- Contreras Nuno Jesus Guillermo
- Cormier Thomas Michael
- Corrales Morales Yasser
- Correa Zanoli Henrique Jose
- Cortes Maldonado Ismael
- Cortese Pietro
- Cosentino Mauro Rogerio
- Costa Filippo
- Costanza Susanna
- Crkovska Jana
- Crochet Philippe
- Cuautle Flores Eleazar
- Cunqueiro Mendez Leticia
- Dahms Torsten
- Dainese Andrea
- Danisch Meike Charlotte
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- Das Debasish
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- Dash Ajay Kumar
- Dash Sadhana
- De Caro Annalisa
- De Cataldo Giacinto
- De Conti Camila
- De Cuveland Jan
- De Falco Alessandro
- De Gruttola Daniele
- De Leone Gay Maria Beatriz
- De Marco Nora
- De Pasquale Salvatore
- De Sudipan
- Deisting Alexander
- Deloff Andrzej
- Deplano Caterina
- Derradi De Souza Rafael
- Dhankher Preeti
- Di Bari Domenico
- Di Mauro Antonio
- Di Nezza Pasquale
- Di Ruzza Benedetto
- Diaz Corchero Miguel Angel
- Dietel Thomas
- Dillenseger Pascal
- Ding Yanchun
- Diozcora Vargas Trevino Aurora
- Divia Roberto
- Djuvsland Oeystein
- Dobrigkeit Chinellato David
- Dobrin Alexandru Florin
- Domenicis Gimenez Diogenes
- Dominguez Rosas Edgar
- Donigus Benjamin
- Dordic Olja
- Duarte Galvan Carlos
- Dubey Anand Kumar
- Dubla Andrea
- Ducroux Laurent
- Dudi Sandeep
- Duggal Ashpreet Kaur
- Dukhishyam Mallick
- Dupieux Pascal
- Ehlers Iii Raymond James
- Elia Domenico
- Endress Eric
- Engel Heiko
- Epple Eliane
- Erazmus Barbara Ewa
- Erhardt Filip
- Espagnon Bruno
- Espinoza Beltran Lucina Gabriela
- Eulisse Giulio
- Eum Jongsik
- Evans David
- Evdokimov Sergey
- Fabbietti Laura
- Faivre Julien
- Fantoni Alessandra
- Fasel Markus
- Feldkamp Linus
- Feliciello Alessandro
- Feofilov Grigorii
- Fernandez Tellez Arturo
- Ferreira Natal Da Luz Pedro Hugo
- Ferretti Alessandro
- Festanti Andrea
- Feuillard Victor Jose Gaston
- Figiel Jan
- Filchagin Sergey
- Finogeev Dmitry
- Fionda Fiorella
- Floris Michele
- Foertsch Siegfried Valentin
- Foka Panagiota
- Fokin Sergey
- Fragiacomo Enrico
- Francescon Andrea
- Francisco Audrey
- Frankenfeld Ulrich Michael
- Franz Degenhardt Hermann
- Fronze Gabriele Gaetano
- Fuchs Ulrich
- Furget Christophe
- Furs Artur
- Fusco Girard Mario
- Gaardhoeje Jens Joergen
- Gagliardi Martino
- Gago Medina Alberto Martin
- Gajdosova Katarina
- Gallio Mauro
- Gameiro Munhoz Marcelo
- Ganoti Paraskevi
- Garabatos Cuadrado Jose
- Garcia-solis Edmundo Javier
- Garg Kunal
- Gargiulo Corrado
- Gasik Piotr Jan
- Gauger Erin Frances
- Germain Marie
- Ghosh Jhuma
- Ghosh Premomoy
- Ghosh Sanjay Kumar
- Gianotti Paola
- Giubellino Paolo
- Giubilato Piero
- Gladysz-dziadus Ewa
- Glassel Peter
- Gomez Coral Diego Mauricio
- Gomez Ramirez Andres
- Gonzalez Ferreiro Elena
- Gonzalez Hernandez Emma
- Gonzalez Zamora Pedro
- Gonzalez Victor
- Gorbunov Sergey
- Gorlich Lidia Maria
- Gotovac Sven
- Grabski Varlen
- Graczykowski Lukasz Kamil
- Graham Katie Leanne
- Greiner Leo Clifford
- Grelli Alessandro
- Grigoras Costin
- Grigoryan Ara
- Grigoryan Smbat
- Grigoryev Vladislav
- Gronefeld Julius Maximilian
- Grosa Fabrizio
- Grosse-oetringhaus Jan Fiete
- Grosso Raffaele
- Guber Fedor
- Guernane Rachid
- Guerzoni Barbara
- Gulbrandsen Kristjan Herlache
- Gunji Taku
- Gupta Anik
- Gupta Ramni
- Haake Rudiger
- Hadjidakis Cynthia Marie
- Hamagaki Hideki
- Hamar Gergoe
- Hamon Julien Charles
- Haque Md Rihan
- Harris John William
- Harton Austin Vincent
- Hassan Hadi
- Hatzifotiadou Despina
- Hayashi Shinichi
- Heckel Stefan Thomas
- Hellbar Ernst
- Helstrup Haavard
- Herghelegiu Andrei Ionut
- Herrera Corral Gerardo Antonio
- Herrmann Florian
- Hess Benjamin Andreas
- Hetland Kristin Fanebust
- Hillemanns Hartmut
- Hills Christopher
- Hippolyte Boris
- Hohlweger Bernhard
- Horak David
- Hornung Sebastian
- Hosokawa Ritsuya
- Hristov Peter Zahariev
- Hughes Charles
- Humanic Thomas
- Hussain Nur
- Hussain Tahir
- Hutter Dirk
- Hwang Dae Sung
- Iga Buitron Sergio Arturo
- Ilkaev Radiy
- Inaba Motoi
- Ippolitov Mikhail
- Islam Md Samsul
- Ivanov Marian
- Ivanov Vladimir
- Izucheev Vladimir
- Jacak Barbara
- Jacazio Nicolo
- Jacobs Peter Martin
- Jadhav Manoj Bhanudas
- Jadlovska Slavka
- Jadlovsky Jan
- Jaelani Syaefudin
- Jahnke Cristiane
- Jakubowska Monika Joanna
- Janik Malgorzata Anna
- Jena Chitrasen
- Jercic Marko
- Jimenez Bustamante Raul Tonatiuh
- Jones Peter Graham
- Jusko Anton
- Kalinak Peter
- Kalweit Alexander Philipp
- Kang Ju Hwan
- Kaplin Vladimir
- Kar Somnath
- Karasu Uysal Ayben
- Karavichev Oleg
- Karavicheva Tatiana
- Karayan Lilit
- Karczmarczyk Przemyslaw
- Karpechev Evgeny
- Kebschull Udo Wolfgang
- Keidel Ralf
- Keijdener Darius Laurens
- Keil Markus
- Ketzer Bernhard Franz
- Khabanova Zhanna
- Khan Mohammed Mohisin
- Khan Palash
- Khan Shuaib Ahmad
- Khanzadeev Alexei
- Kharlov Yury
- Khatun Anisa
- Khuntia Arvind
- Kielbowicz Miroslaw Marek
- Kileng Bjarte
- Kim Byungchul
- Kim Daehyeok
- Kim Dong Jo
- Kim Hyeonjoong
- Kim Jinsook
- Kim Jiyoung
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- Kim Se Yong
- Kim Taesoo
- Kirsch Stefan
- Kisel Ivan
- Kiselev Sergey
- Kisiel Adam Ryszard
- Kiss Gabor
- Klay Jennifer Lynn
- Klein Carsten
- Klein Jochen
- Klein-boesing Christian
- Klewin Sebastian
- Kluge Alexander
- Knichel Michael Linus
- Knospe Anders Garritt
- Kobdaj Chinorat
- Kohler Markus Konrad
- Kollegger Thorsten
- Kondratev Valerii
- Kondratyeva Natalia
- Kondratyuk Evgeny
- Konevskikh Artem
- Konyushikhin Maxim
- Kopcik Michal
- Kour Mandeep
- Kouzinopoulos Charalampos
- Kovalenko Oleksandr
- Kovalenko Vladimir
- Kowalski Marek
- Koyithatta Meethaleveedu Greeshma
- Kralik Ivan
- Kravcakova Adela
- Kreis Lukas
- Krivda Marian
- Krizek Filip
- Kryshen Evgeny
- Krzewicki Mikolaj
- Kubera Andrew Michael
- Kucera Vit
- Kuhn Christian Claude
- Kuijer Paulus Gerardus
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- Kuryakin Alexey
- Kushpil Svetlana
- Kweon Min Jung
- Kwon Youngil
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- Lardeux Antoine Xavier
- Lattuca Alessandra
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- Lehas Fatiha
- Lehner Sebastian
- Lehrbach Johannes
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- Leogrande Emilia
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- Levai Peter
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- Lindenstruth Volker
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- Lopez Xavier Bernard
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- Luettig Philipp Johannes
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- Luparello Grazia
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- Marchisone Massimiliano
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- Mihaylov Dimitar Lubomirov
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- Myrcha Julian Wojciech
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- Negrao De Oliveira Renato Aparecido
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- Nomokonov Petr
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- Nyanin Alexander
- Nystrand Joakim Ingemar
- Oeschler Helmut Oskar
- Oh Hoonjung
- Ohlson Alice Elisabeth
- Okubo Tsubasa
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- Oliver Michael Henry
- Onderwaater Jacobus
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- Oskarsson Anders Nils Erik
- Otwinowski Jacek Tomasz
- Oyama Ken
- Ozelin De Lima Pimentel Lais
- Pachmayer Yvonne Chiara
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- Paic Guy
- Palni Prabhakar
- Pan Jinjin
- Pandey Ashutosh Kumar
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- Publication date
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- Field of study
Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
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- Sampietro G. M. (Ospedale di Rho â ASST Rhodense)
- San Francisco (UCSF))
- Sanchez Cabezudo Noguera F.
- Sanchez Gonzalez J.
- Sanchez Jimenez R.
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- Sarre C. (Instituto Nacional de Ciencias MĂ©dicas y NutriciĂłn âSalvador ZubirĂĄnâ). Morocco: Amrani L.
- Sartarelli L.
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- Sasia D.
- SaudĂ S. (Hospital Universitario Miguel Servet)
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- Sauvat F. (CHU RĂ©union). Romania: Bezede C.
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- Sayyed R. (Patel Hospital)
- Scabini S.
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- Schiergens T.
- Schineis C. (Charité University Medicine
- Schizas D.
- Schlesinger N.
- Schwartz P.
- Scott L. (Pinderfields Hospital)
- Scotton G. (St Moritz Hospital)
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- Sechenov Medical State University)
- Seebah K.
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- Seguin-Givelet A.
- Sehgal T.
- Selmani J.
- Semina E. (Moscow Research and Educational Center
- Senossi O.
- Serevina O. L.
- Serralta de Colsa D. (Infanta SofĂa University Hospital)
- Serrano GonzĂĄlez J. (Hospital Universitario de TorrejĂłn de Ardoz)
- Serrano-Navidad M.
- Sert Ä°.
- Seymour Z. (Ysbyty Gwynedd). USA: Haynes A.
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- Shah Z. A.
- Shaikh I.
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- Sheridan K.
- Sherief M.
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- Subramaniam S. (Queen Elizabeth Hospital and Universiti Malaysia Sabah
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- TU Dresden)
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- Universiti Sains Malaysia)
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- YĂŒksel E. (Kocaeli University Teaching Hospital)
- Zafar S. N. (University of Wisconsin)
- Zakaria A. D.
- Zakaria Z. (School of Medical Sciences and Hospital
- Zambon M. (Policlinico Umberto I Sapienza University of Rome)
- Zanus G. (Caâ Foncello Treviso â DISCOG â UniversitĂ di Padova)
- Zegarac M. (Institute for Oncology and Radiology of Serbia)
- ZeliÄ M. (University Hospital Center Rijeka)
- Zengin A. K. (Istanbul Universty â CerrahpaĆa Medical Faculty)
- Zerbib P. (CHU Lille)
- Zervas K.
- Zese M. (Santa Maria degli Angeli Hospital ULSS 5 â Adria)
- Zhang H. (Concord Repatriation General Hospital)
- Zizzo M. (Azienda UnitĂ Sanitaria Locale â IRCCS di Reggio Emilia)
- Zografos C. (Laiko University Hospital)
- Zorrilla OrtĂșzar J. (Hospital General Universitario Gregorio Marañón)
- Zourntou S. (General Hospital of Larissa âKoutlimpaneio and Triantafylleioâ)
- Zubaidi A. M. (King Saud University). Serbia: AleksiÄ L.
- Ăngelo M.
- Ăelebi F.
- Ăolak E.
- Ăfner D. (Medical University of Innsbruck)
- Ăhlberger L.
- Ăzçelık M. F.
- ĂÄĂŒcĂŒ H.
- ĂberrĂŒck L.
- Äoza I.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic
Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study
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- Aawsaj Y.
- Abad Gurumeta A.
- Abad-Motos A.
- Abate E.
- Abatini C.
- Abbadessa F.
- Abbas A. M.
- Abbassi-Ghadi N.
- Abbott D.
- Abbott T.
- Abd Elazeem H. A. S.
- Abdalla M.
- Abdallah M.
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- Abdel Jalil R.
- Abdeldayem H.
- Abdelkader Salama I.
- Abdelkarem M. M.
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- Publication venue
- 'American Society of Clinical Oncology (ASCO)'
- Publication date
- 01/01/2021
- Field of study
PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19âfree surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19âfree surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19âfree surgical pathways. Patients who underwent surgery within COVID-19âfree surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19âfree surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity scoreâmatched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19âfree surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19âfree surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks
Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.
- Author
- Aawsaj Y.
- Abad Gurumeta A.
- Abad-Motos A.
- Abate E.
- Abatini C.
- Abbadessa F.
- Abbas A. M.
- Abbassi-Ghadi N.
- Abbott D.
- Abbott T.
- Abd Elazeem H. A. S.
- Abdalla M.
- Abdallah M.
- Abdel Al S.
- Abdel Jalil R.
- Abdeldayem H.
- Abdelkader Salama I.
- Abdelkarem M. M.
- Abdelkarim M.
- Abdelmajeed A.
- Abdelrahman A.
- Abdelrahman S.
- Abdelsamed A.
- Abdou M.
- Abdulkareem A.
- Abdulwahed E.
- Abdur-Rahman L.
- Abel M. K.
- Abellan M.
- Aboelkassem Ibrahim A.
- Abosamak N. E.
- Abou Chaar M. K.
- Abou-Khalil J.
- Abouassi A.
- Aboulkassem H.
- Abreu Da Silva A.
- Abu J.
- Abu Za'nouneh F. J.
- Abu-Nayla I.
- Abubakar A.
- Acebes Garcia F.
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- Publication venue
- J Clin Oncol
- Publication date
- 01/01/2020
- Field of study
PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks
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