Uterus didelphys with multiple fibroids: A case report

Uterine anomalies are congenital malformations caused by fusion or resorption defects during embryogenesis. Uterus didelphys, or a double uterus, is a rare condition that occurs in female fetuses as they develop in the womb. Here we report a case of a 46 year old virginal female with uterus didelphys along with multiple fibroids of both uteri and a right ovarian cyst. The patient underwent a total abdominal hysterectomy with adnexa removal. The specimen showed leiomyoma of uterus with ovarian endometriosis

Uterus didelphys with multiple fibroids: A case report

Uterine anomalies are congenital malformations caused by fusion or resorption defects during embryogenesis. Uterus didelphys, or a double uterus, is a rare condition that occurs in female fetuses as they develop in the womb. Here we report a case of a 46 year old virginal female with uterus didelphys along with multiple fibroids of both uteri and a right ovarian cyst. The patient underwent a total abdominal hysterectomy with adnexa removal. The specimen showed leiomyoma of uterus with ovarian endometriosis

Use of Foley\u27s catheter balloon tamponade to control placental site bleeding resulting from major placenta previa during cesarean section

Aim: To evaluate the effect of 2-way Foley\u27s catheter balloon tamponade on controlling immediate postpartum hemorrhage (PPH) in cases of major placenta previa during cesarean section (CS). Methods: We evaluated women with placenta previa from May to November 2015. Women with immediate PPH during CS due to major placenta previa were managed by 2-way Foley\u27s catheter balloon tamponade when medical treatment failed, and before any surgical intervention. Results: Twenty patients, had major placenta previa, were delivered by elective CS and complicated by immediate PPH. Three placenta accreta patients (15%) underwent hysterectomy, 17 (85%) were managed by the 2-way Foley\u27s catheter balloon tamponade. In two patients, Foley\u27s catheter balloon failed to control bleeding and hysterectomy was done immediately. However, Foley\u27s catheter balloon successfully treated the remaining 15 patients. The median bleeding during the operation was 1522.5 (± 619.29) ml. None of them presented complications related to this procedure or required any further invasive surgery. Conclusion: The 2-way Foley\u27s catheter tamponade could be an option to control immediate postpartum hemorrhage resulting from major placenta previa during the cesarean section. This method is simple, cheap, nearly non-invasive and should be considered to reduce the risk of peripartum hysterectomy

Polycystic kidney disease with unilateral ventriculomegaly: a case report

Polycystic Kidney Disease (PKD) is an autosomal recessive disease with an incidence of about 1 in 30 000 births. It characterized by multiple cysts which filled by fluid that can ultimately impede kidney function leading to degeneration of renal tissue and renal failure. Oligo or anhydramnios is frequently present but not invariably so, suggesting that some degree of renal function is retained in some PKD cases. We present a 30 year old woman, gravida 5, para 4, at 22 weeks of gestation with ultrasound findings of autosomal recessive PKD, unilateral ventriculomegaly and marked oligohydramnios. Ventriculomegaly is a brain condition that occurs when the width of the atrium of the lateral ventricle is greater than 10 mm and occurs in 0.3-1.5 births per 1000. The association between autosomal recessive PKD and unilateral ventriculomegaly is not well understood and needs further evaluation

Polycystic kidney disease with unilateral ventriculomegaly: a case report

Polycystic Kidney Disease (PKD) is an autosomal recessive disease with an incidence of about 1 in 30 000 births. It characterized by multiple cysts which filled by fluid that can ultimately impede kidney function leading to degeneration of renal tissue and renal failure. Oligo or anhydramnios is frequently present but not invariably so, suggesting that some degree of renal function is retained in some PKD cases. We present a 30 year old woman, gravida 5, para 4, at 22 weeks of gestation with ultrasound findings of autosomal recessive PKD, unilateral ventriculomegaly and marked oligohydramnios. Ventriculomegaly is a brain condition that occurs when the width of the atrium of the lateral ventricle is greater than 10 mm and occurs in 0.3-1.5 births per 1000. The association between autosomal recessive PKD and unilateral ventriculomegaly is not well understood and needs further evaluation

The prevalence and the clinical characteristics of metabolic syndrome patients admitted to the cardiac care unit

AbstractObjectivesMetabolic syndrome (MetS) is a group of multiple cardiovascular risk factors, including dysglycemia, central obesity, high cholesterol, and hypertension. Cardiovascular disease is one of the most common complications of MetS. Recent studies showed that prevalence of MetS among patients admitted with acute coronary syndrome was as high as 46%.DesignWe conducted a cross-sectional study of 203 patients at the two main hospitals in Ta’if, Saudi Arabia. Patients older than 18years who were admitted to the Cardiac Care Unit (CCU) between the months of August 2013 and June 2014 were asked to participate. MetS diagnosis was made based on the International Diabetes Federation definition.ResultsA total of 203 patients participated, with 59.1% male and 40.9% were female. The mean age was 60.9 years with a mean body mass index of 28.97kg/m2 and a mean waist circumference of 95.45cm. The prevalence of MetS was 47.8%, primarily among obese female patients who reported sedentary lifestyles. Additionally, MetS patients were more likely to be admitted with heart failure (p<0.05) and more likely to have moderate-to-severe left-ventricular hypertrophy (LVH; p<0.05) relative to non-MetS patients.ConclusionOf the patients admitted to the CCU, 47.8% had MetS, with those patients likely to be female and obese. Furthermore, MetS patients were more likely to be admitted with heart failure and suffer from moderate-to-severe LVH

The unexpected presence of a huge cystic hygroma with thanatophoric dysplasia type I: a case report

Introduction: The presence of a thin-walled, multicystic structure posterior to the fetal head and neck with an intact vertebral column is known as a cystic hygroma. Thanatophoric dysplasia is the most lethal skeletal dysplasia. Thanatophoric dysplasia (TD) is an autosomal dominant disorder with two phenotypes. TD type I is characterized by a normal shaped skull with bowed femurs and micromelia, while TD type II is characterized by straight femurs with a clover-leaf deformity of the skull and micromelia. We report here a case of thanatophoric dysplasia type I associated with cystic hygroma, this association needs further evaluation. Case history: A 30 year old woman was referred at 26 weeks of gestation because of marked polyhydramnios. Ultrasonographic examination of the fetus revealed a narrow chest, protuberant abdomen, short curved femur, normal shaped skull with accidentally cystic hygroma were present. No other anomalies were detected. We explained to the patient the nature and severity of the anomaly and the patient preferred the termination of pregnancy. Induction of abortion was done successfully. Conclusion: This case report has highlighted the association between cystic hygroma and thanatophoric dysplasia type I. To our knowledge, this is the first report in the literature reporting the association of cystic hygroma and thanatophoric dysplasia type I. We believe that this case is useful for obstetricians and pediatricians. We also highly recommend the genetic evaluation of the fetus and parents

Undiagnosed endometrial abnormalities in women with normal hysterosalpingography scheduled for IVF: prospective evaluation of three-dimensional transvaginal ultrasound versus office hysteroscopy

Objectives: To compare the diagnostic accuracy of three-dimensional transvaginal ultrasound (3D-US) to office hysteroscopy (OH) in the screening of uterine cavity with normal hysterosalpingography (HSG) findings for subtle endometrial abnormalities before in vitro-fertilization (IVF). Methods: A prospective cohort cost-modeling study was carried out in a University hospital. We included 120 infertile women with a normal uterine cavity on HSG scheduled for IVF. All cases were evaluated by 3D-US, and the results were compared with OH findings. Results: OH revealed cavitary endometrial lesions (CLs) in thirty-four women (28.3%). Endometrial polyps were the most common detected lesions (16, 47.1%). 3D-US had 88.2% sensitivity, 96.5% specificity, 90.9% positive predictive value, 95.4% negative predictive value, and 94.2% overall accuracy for CLs. The overall agreement between 3D-US and OH was near-perfect (κ=0.86, 95% CI=0.75-0.96). Irregular menstrual bleeds and prior endometrial procedures were significant predictors for CLs (aOR=24.96, 95% CI=2.71–230.04, P=0.005, aOR=9.16, 95% CI=2.13–39.3, P=0.002, respectively). A selective screening strategy discerning OH to women with these predictors and/or women with abnormal 2D-US would have an NPV of 92.8 % with substantial cost benefits. Conclusions: In the pre-IVF work up, 3D-US, a non-invasive imaging modality, seems to be nearly comparable to OH. Office hysteroscopy screening prioritizing women with abnormal 2D-US, irregular menstrual periods and/or prior endometrial traumatization could yield a satisfactory cost-effective approach for identifying endometrial lesions

Twin pregnancy with complete hydatidiform mole and coexisting fetus following ovulation induction with a non-prescribed clomiphene citrate regimen: a case report

<p>Abstract</p> <p>Introduction</p> <p>Twin pregnancy with complete hydatidiform mole represents a very rare obstetric problem. Management of such cases is always problematic because the possibility of fetal survival should always be weighed against the risk of complications of molar pregnancy.</p> <p>Case presentation</p> <p>A 34-year-old Caucasian woman presented to our center with mild vaginal bleeding. Our patient was 16 weeks pregnant after a seven-year period of primary infertility. She became pregnant following a non-prescribed regimen of clomiphene citrate extending from the second day to the 13th day of her last cycle. A transabdominal ultrasound examination revealed a twin pregnancy with complete hydatidiform mole and a coexisting fetus. Serum β human chorionic gonadotropin was falsely low as identified by serial dilution of the sample (the 'hook effect'). Our patient refused termination of pregnancy and she was hospitalized for strict observation and follow-up. Unfortunately, she developed an attack of severe vaginal bleeding and a hysterotomy was performed. The fetus died shortly after birth.</p> <p>Conclusions</p> <p>Twin pregnancy with complete hydatidiform mole represents a matter of controversy. We suggest that conservation should always be considered whenever tertiary care services and strict observation are available.</p

Investigation of the Impact of Mycogenic Titanium and Selenium Nanoparticles on Fusarium Wilt Infection of Tomato Plant

We applied biosynthesized titanium and selenium nanoparticles, prepared using a fungal water extract of Trichoderma harzianum (T. harzianum), to eradicate tomota wilt infection. Transmission electron microscopy (TEM), Scanning electron microscopy (SEM), Energy Dispersive X-Ray analysis, and Transmission electron microscopy/X-ray diffraction (TEM/XRD) techniques were used to characterize the spherical metal nanoparticles, whose diameters were 16.0 nm for selenium nanoparticles (SeNPs) and 50.0 nm for titanium nanoparticles (TiNPs). This confirmed the efficient biosynthesis of the nanoparticles. Under greenhouse conditions, the effectiveness of TiNPs and SeNPs produced by nonpathogenic fungi (T. harzianum) against the pathogen responsible for the tomato wilt disease, Fusarium oxysporum (F. oxysporum), was studied. Based on the results, the most efficient method for combating the pathogen that causes tomato wilt was used in open fields, whereas pot studies were conducted in greenhouse conditions. All tested treatments considerably lowered tomato plant wilt disease in both the greenhouse and the open field. The disease severity was reduced by 20.4% using TiNPs at high concentrations of 150 ppm and by 41.5% using SeNPs. Compared to conventional antibiotics, the antibacterial activity assessment of the biosynthesized TiNPs and SeNPs revealed a significant effect versus pathogenic bacteria and fungi, with a negligible influence on the examined human and animal microflora. The findings showed that biosynthesized TiNPs and SeNPs can be applied to suppress the plant pathogen F. oxysporum in a way that is safe for the microflora of humans and animals. This is the first instance where the nanocidal activity of biological TiNPs and SeNPs has been used against the pathogen that causes tomato wilt