2,085 research outputs found
Dynamic Response Of Multistory Reinforced Concrete Buildings Having Different Types Of Isolators A Parametric Study
Approaches to isolating the base have become a crucial element in enhancing quality stability during a seismic earthquake load. In the present day, base detachment is routinely utilized as an essential arrangement technique for structures and frameworks in seismically active zones. This paper aims towards the dynamic analysis of a multi-story RCC building with various parameters. For the sake of study and verification, a model of a ten-story RCC building with a symmetrical floor plan is considered. The study was conducted using SAP 2000's time-history-based software. In this paper,72 models were studied based on various parameters such as bay width, number of bays, number of floors, and various isolators (Lead Rubber Bearings, Friction Pendulum Bearing, Fixed, and Hinge). The reaction of the structure, for example, time period, base shear, and story displacements are studied and a comparison is made. The paper showed the clear superiority of isolation methods in resisting earthquakes. The friction pendulum support has been the preferred type due to the lowest drift story of the building when it was compared with other support systems. Also, as the results showed a high time period when using the lead rubber bearings, which shows the model's ability to withstand earthquakes
Role of Visual Evoked Potentials in Multiple Sclerosis
Background: Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system (CNS) affecting young adults and is considered as the leading cause of non traumatic neurological disability of young adults affecting nearly 2 million people worldwide. The pathogenesis of MS is at best incompletely understood. There are several proposed mechanisms that may be important in the production of MS plaques: autoimmunity, environment and heredity. Deviation of immune responses in a genetically susceptible patient plays a central role in its pathogenesis. Electrophysiological, spinal tap and Radiological tools are important laboratory investigations and have added so much to the clinical diagnosis and for the classification of MS. It was found that visual function and conduction has been changed in patients with multiple sclerosis.
Objectives: The aims of the study is to estimate and evaluate the visual evoked potential (VEP) parameters in patients with MS and its relation to their disability degree (using the expanded disability status scale score "EDSS") and visual presentation of them in comparison with healthy individuals.
Patients and Methods: 112 patients with multiple sclerosis and 50 subjects without any neurological or psychiatric diseases as control group were recruited in this study. The cases were collected from Baghdad teaching hospital, MS center, Baghdad, Iraq at the period from May 2012 to April 2013, and studied at the unit of electrophysiology in Al-Shaheed Ghazi Al-Hareri Hospital in the Medical city. All patients and control groups were tested for VEP.
Results: The present study showed a significant increase in the P100 latency and inter-ocular (IO) latency difference and non statistical significant decrease in the IO amplitude difference in patients group than the control group. Also among patients group there was positive linear correlation between the severity of the disease measured by EDSS score and P100 latency while negative linear correlation with the amplitude.
Conclusion: There was a higher percent of patients with defective VEP parameters and so their visual pathway even if it was asymptomatic, in addition to their relation with patients` disability than the control group, making it easy to quantify and predict MS disability objectively.
Keywords: Multiple sclerosis, Expanded Disability Status Scale, VEP
Synthesis of Some novel Azomethine Oxide Derived from Aromatic Oximes and their Anti-microbial Studies
The organic compound category known as azomethine oxides has garnered significant attention due to its potential for bioactive and pharmacological effects, as well as its role in organic syntheses. Existing literature offers various methods for producing derivatives of these compounds. This study, in particular, concentrates on the creation of several aromatic oximes through the reduction of corresponding aldehydes. Furthermore, these oximes are employed in the generation of new azomethine oxides through a condensation reaction with selected aldehydes. The molecular structure of the synthesized azomethine oxides is determined using techniques such as Fourier-transform infrared spectroscopy, 1H-NMR, and 13C-NMR. Finally, the antimicrobial effectiveness of these compounds was assessed against Escherichia coli (gram-negative bacteria), Staphylococcus aureus (gram-positive bacteria), and Candida albicans (fungus). The synthesized compounds were obtained with high purity and yielded excellent results. Furthermore, the data demonstrates that these azomethine oxides exhibit significant antimicrobial activity when compared to standard drugs
ANURIA SECONDARY TO HOT WEATHER-INDUCED HYPERURICAEMIA: DIAGNOSIS AND MANAGEMENT
There is little information on the management of anuria secondary to severe
volume depletion or as a rare manifestation of heat stroke in areas of the world with very hot
summers. We present our experience with hot weather-induced hyperuricaemia in Kuwait
ANURIA SECONDARY TO HOT WEATHER-INDUCED HYPERURICAEMIA: DIAGNOSIS AND MANAGEMENT
There is little information on the management of anuria secondary to severe
volume depletion or as a rare manifestation of heat stroke in areas of the world with very hot
summers. We present our experience with hot weather-induced hyperuricaemia in Kuwait
Histological and Immunocytochemical Studies on the Buccal Minor Salivary Glands in Rabbits
Buccal minor salivary glands are continuously produced saliva ,which is important to lubricate the buccal mucosa.Buccal glands were collected from thirty adult male rabbits. Wall of cheek were removed from anesthetized rabbits at the place of buccal glands. Paraffin sections stained of the glands were stained by H and E stain, PAS reaction and alcian blue (pH 2.5) stain. Immunocytochemistry to stain actin myofilaments of myoepithelial cell were applied. It’s were mixed glands, but predominantly mucous in rabbit. The serous cells were represented by demilunes capping mucous tubules together with small number of serous acini. The myoepithelial cells (MECs) were seen around the mucous secretory units and around the intercalated ducts and striated ducts .The MECs were positively stained immunohistochemically for actin myofilaments. The cells secreotory mucous acini estimation of number and diamstter of ducts and thickest of connective tissue as well as number of acini mucous, serous acini and intercalated ducts and describe of the MECs
Determination of the Total Sulphur Content in Khurmala and Guwayar Oil Fields of Kurdistan Region, Iraq
Five different samples of crude oil were evaluated. Three samples are from Khurmala crude oil field, and two samples are from the Guwayer crude oil field. All samples were evaluated to distinguish between qualities of both fields which are important sources of crude oil in the Kurdish Region. The specific gravity, API gravity, and the sulphur content were measured for all samples. Energy Dispersive X-Ray Fluorescence (EDXRF) was used to determine total sulfur content, a hydrometer was used to measure specific gravity and by using a mathematical equation we can find API gravity. By estimating these three parameters, crude oil of both fields were evaluated. In the samples of Guwayar oil field that measured the total sulfur in one of the well is 0.607 %(mean) wt and in second well was 0.6905 % wt(mean), while the total sulphur content in samples of three wells in Khurmala oil field were 2.3324% wt(mean), 2.1016% wt(mean), and 0.7362% wt(mean). We are 95% confident that there is no significant difference and we rejected the null hypothesis. There is strong relationship between sulphur content wt. % and specific gravity of the samples
Transportation of Cuttings in Inclined Wells
One of the most important functions performed by drilling fluid is the removal of cutting from the bottom of the hole to the surface. This function must be performed efficiently if not, the cuttings produced during drilling process will accumulate in the annulus. This problem in directional drilling is featured by gravitational forces. Problems resulting from inefficient cutting transport include pipe stuck, wear of bit, reduction in penetration rate, high torque and drag with many other problems encountered. In high angle deviated wells, the cutting goes through a complex path to the surface where some of the cuttings gravitate to the low side of the well. Reduction in any problem associated with improper cutting transport require good understanding in cutting transport mechanisms. This research focuses on calculating the minimum annular velocity of drilling fluid and minimum pump flow rate which is required to achieve hole- cleaning and lifting of the cutting to the surface, taking into consideration the main parameters that affect the coring capacity of the drilling fluid, for this purpose, data of a deviated well (X) located in Kurdistan region of Iraq is collected to determine slip velocity, annular velocity, critical flow rate and carrying capacity index taking in consideration the mud used and the angle of the deviation using the drilling formula spread sheet V1.6
Whole genomic sequence analysis of \u3ci\u3eBacillus infantis\u3c/i\u3e: defining the genetic blueprint of strain NRRL B-14911, an emerging cardiopathogenic microbe
Background: We recently reported the identification of Bacillus sp. NRRL B-14911 that induces heart autoimmunity by generating cardiac-reactive T cells through molecular mimicry. This marine bacterium was originally isolated from the Gulf of Mexico, but no associations with human diseases were reported. Therefore, to characterize its biological and medical significance, we sought to determine and analyze the complete genome sequence of Bacillus sp. NRRL B-14911.
Results: Based on the phylogenetic analysis of 16S ribosomal RNA (rRNA) genes, sequence analysis of the 16S-23S rDNA intergenic transcribed spacers, phenotypic microarray, and matrix-assisted laser desorption ionization time-offlight mass spectrometry, we propose that this organism belongs to the species Bacillus infantis, previously shown to be associated with sepsis in a newborn child. Analysis of the complete genome of Bacillus sp. NRRL B-14911 revealed several virulence factors including adhesins, invasins, colonization factors, siderophores and transporters. Likewise, the bacterial genome encodes a wide range of methyl transferases, transporters, enzymatic and biochemical pathways, and insertion sequence elements that are distinct from other closely related bacilli.
Conclusions: The complete genome sequence of Bacillus sp. NRRL B-14911 provided in this study may facilitate genetic manipulations to assess gene functions associated with bacterial survival and virulence. Additionally, this bacterium may serve as a useful tool to establish a disease model that permits systematic analysis of autoimmune events in various susceptible rodent strains
Non-penetrating deep sclerectomy versus combined trabeculotomy–trabeculectomy in primary congenital glaucoma
Background: The primary mode of therapy in children with primary congenital glaucoma (PCG) and mild or no corneal edema is goniotomy, which has a high success rate. However, in developing countries, the diagnosis of PCG is usually delayed, and corneal cloudiness interferes with goniotomy. Therefore, trabeculotomy may be the best choice in such eyes. We compared the short-term efficacy and safety of primary combined trabeculotomy–trabeculectomy (primary CTT) with that of non-penetrating deep sclerectomy (NPDS) in managing PCG.
Methods: This prospective, randomized, comparative study included patients with PCG referred to Al-Azhar University Hospitals within a 1-year period. Eyes were randomly allocated to one of two groups: eyes in NPDS group underwent NPDS, and those in primary CTT group underwent primary CTT. Baseline and frequent postoperative assessments of intraocular pressure (IOP), cup-to-disc ratio (C/D ratio), corneal diameter, and axial length were performed for up to 6 months. The success rates were recorded in both groups.
Results: Forty eyes of 26 patients were included, with 20 eyes allocated to each group. The mean (standard deviation) age of all patients was 12.9 (9.5) months, with comparable ages and sex ratios between groups (both P > 0.05). Both groups demonstrated a significant reduction in IOP and C/D ratio at each postoperative visit compared to the baseline visit (all P < 0.001), with no significant difference detected between the groups (all P > 0.05), except for a significantly lower IOP in NPDS group at 1 month (P < 0.05). The corneal diameter and axial length were comparable between groups at baseline and remained unchanged at all postoperative visits (all P > 0.05). The groups had comparable success rates (P > 0.05). No serious complications were detected.
Conclusions: CTT and NPDS both yielded reasonable IOP control and reversal of cupping in eyes with PCG. We observed equal effectiveness of the surgical procedures without major safety concerns. Further large-scale clinical trials with longer follow-up periods are needed to verify our preliminary findings
- …