Synthesis of Polyfunctionalized Amino Furans with Long Conjugated Aromatic Systems Using Nucleophilic Aromatic Isocyanide

Polyfunctionalized amino furans with long conjugated aromatic systems have been synthesized by three component reaction of aldehydes, acetylenic esters and aromatic nucleophilic isocyanide

Highly Efficient Selective Oxygenation of Sulfides to Sulfoxides by Oxalic Acid Dihydrate in the Presence of H2O2

A highly efficient method for the oxidation of sulfides to sulfoxides using oxalic acid dihydrate in the presence of hydrogen peroxide has been developed. A versatile procedure for the oxidation of sulfides to sulfoxides without any over-oxidation to sulfones has been reported. This procedure cleanly oxidizes sulfides to the corresponding sulfoxides in excellent yields at ambient temperature

Synthesis of Polyfunctionalized Amino Furans with Long Conjugated Aromatic Systems Using Nucleophilic Aromatic Isocyanide

Polyfunctionalized amino furans with long conjugated aromatic systems have been synthesized by three component reaction of aldehydes, acetylenic esters and aromatic nucleophilic isocyanide

Carbon–Heteroatom Bond Formation via Coupling Reactions Performed on a Magnetic Nanoparticle Bed

Cross-coupling reactions leading to carbon–heteroatom bonds yield compounds that attract substantial interest due to their role as structural units in many synthetic protocols for bioactive and natural products. Therefore, many research works aim at the improvement of heterogeneous catalytic protocols. We have studied the use of magnetite nanoparticles and solid base compounds in organic synthetic reactions in carbon–heteroatom bond formation because they can be flocculated and dispersed, and reversibly controlled by applying a magnetic field. In this work, we have developed an efficient and simple synthetic approach for the C–O/C–N cross-coupling reaction under ligand-free conditions by using CuI as a catalyst and KF/Fe3O4 as a base. We performed the nucleophilic aromatic substitution of electron-deficient aryl halides and phenols. It was found that both the solvent nature and the base have a profound influence on the reaction process. This approach affords good to excellent yields of arylated products. KF/Fe3O4 displayed convenient magnetic properties and could be easily separated from the reaction using a magnet and recycled several times without significant loss of catalytic activity. This method has been successfully investigated for the Ullmann coupling reaction

Use of phosphorylated chitosan/alumina nanoadditives for polymer performance improvement

• Financiación de acceso abierto gracias al acuerdo CRUE-CSIC con Springer NatureEn esta investigación, se ha desarrollado una nueva generación de nanocompuestos ternarios nanocompuestos ternarios a base de poli(tereftalato de etileno) (PET), quitosano fosforilado y nanopartículas de alúmina y nanopartículas de alúmina de superficie modificada. cuatro pasos. El proceso de fosforilación se dirigió de fósforo como agente ignífugo en el PET final. retardante de llama en el nanocompuesto final de PET. Asimismo, nanoalúmina respetuosa con el medio ambiente en la matriz de PET para mejorar sus propiedades térmicas térmicas del PET en colaboración con ancladas orgánicamente. Alternativamente, la presencia de nanopartículas de alúmina modificada biosegura en combinación con quitosano fosforilado simultáneamente simultáneamente la actividad antibacteriana y las térmicas de la matriz de PET. Además, los efectos de las nanopartículas de quitosano fosforilado y alúmina en la morfología y las propiedades térmicas de los nanocompuestos. térmicas de los nanocompuestos. enfoques. Se analizaron la estructura y la distribución de las nanopartículas en el PET se analizaron mediante microscopía microscopía electrónica de barrido. Además, se realizaron calorimetría diferencial de barrido y termogravimetría. de las propiedades térmicas de los nanocompuestos preparados. de los nanocomposites preparados. Los nanocompuestos preparados mostraron una mejor actividad de inhibición del crecimiento contra la bacteria Escherichia coli en comparación con el PET y PET/chitosán fosforilado. Además, las características térmicas de los nanocompuestos mejoraron considerablemente.In this research, a new generation of ternary nanocomposites based on poly(ethylene terephthalate) (PET), phosphorylated chitosan and surface modified alumina nanoparticles were fabricated in four steps. The phosphorylation process was targeted for the insertion of phosphorus moieties as a flame retardant agent in the final PET nanocomposite. Likewise, environmentally friendly nano-alumina was used for PET matrix to improve the thermal properties of PET in collaboration with organic anchored phosphorus moieties. Alternatively, the presence of bio-safe modified alumina nanoparticles in combination with phosphorylated chitosan simultaneously improved the antibacterial activity and thermal properties of the PET matrix. Furthermore, the effects of the phosphorylated chitosan and alumina nanoparticles on the morphology and thermal properties of nanocomposites were inspected by different approaches. The structure and distribution of the nanoscale particles in PET were analyzed by scanning electron microscopy. In addition, differential scanning calorimetry and thermogravimetric analyses were used for the in-depth evaluation of the thermal properties of prepared nanocomposites. Prepared nanocomposites showed better growth inhibition activities against Escherichia coli bacteria compared to the PET and PET/phosphorylated chitosan samples. Also, the thermal characteristics of prepared nanocomposites were considerably improved.• Junta de Extremadura. Consejería de Educación y Empleo. Ayudas GR21107 e GR18171 • Iran Nanotechnology Initiative Council. SubvencionespeerReviewe