The new soliton solutions for long and short-wave interaction system

The goal of this paper is to discover modern soliton solutions to long and short-wave interaction system by procedures called extended rational sine-cosine and rational sinh-cosh methods. We assume that the equation has a hypothetical soliton solutions. By reorganizing the resulting equations, we obtain a system of equations. Using Maple software, we get unknown coefficients in the system and writing them in the original equation, we obtain new solition solutions of the equation. The results show that the soliton solutions generated by the method for the long and short-wave interaction system are bright, kink type, bright periodic and dark solutions. We provided 3-D figures to illustrate the solutions. Computational results indicate that the method employed in this paper is superior than some other methods used in the literature to solve the same system equations

Hydrogel nanocomposite based on alginate/zeolite for burn wound healing: In vitro and in vivo study

Objective(s): The main objective of the current assay was to evaluate the antibacterial and regenerative effects of hydrogel nanocomposite containing pure natural zeolite (clinoptilolite) integrated with alginate (Alg) as wound healing/dressing biomaterials.Materials and Methods: The zeolites were size excluded, characterized by SEM, DLS, XRD, FTIR, and XRF, and then integrated into Alg hydrogel followed by calcium chloride crosslinking. The Alg and alginate zeolite (Alg/Zeo) hydrogel was characterized by swelling and weight loss tests, also the antibacterial, hemocompatibility, and cell viability tests were performed. In animal studies, the burn wound was induced on the back of rats and treated with the following groups: control, Alg hydrogel, and Alg/Zeo hydrogel.Results: The results showed that the hydrodynamic diameter of zeolites was 367 ± 0.2 nm. Zeolites did not show any significant antibacterial effect, however, the hydrogel nanocomposite containing zeolite had proper swelling as well as hemocompatibility and no cytotoxicity was observed. Following the creation of a third-degree burn wound on the back of rats, the results indicated that the Alg hydrogel and Alg/Zeo nanocomposite accelerated the wound healing process compared with the control group. Re-epithelialization, granulation tissue thickness, collagenization, inflammatory cell recruitment, and angiogenesis level were not significantly different between Alg and Alg/Zeo nanocomposite.Conclusion: These findings revealed that although the incorporation of zeolites did not induce a significant beneficial effect in comparison with Alg hydrogel, using zeolite capacity in hydrogel for loading the antibiotics or other effective compounds can be considered a promising wound dressing

Clinical presentation and natural history of infantile-onset ascending spastic paralysis from three families with an ALS2 founder variant.

Biallelic mutations of the alsin Rho guanine nucleotide exchange factor (ALS2) gene cause a group of overlapping autosomal recessive neurodegenerative disorders including infantile-onset ascending hereditary spastic paralysis (IAHSP), juvenile primary lateral sclerosis (JPLS), and juvenile amyotrophic lateral sclerosis (JALS/ALS2), caused by retrograde degeneration of the upper motor neurons of the pyramidal tracts. Here, we describe 11 individuals with IAHSP, aged 2-48 years, with IAHSP from three unrelated consanguineous Iranian families carrying the homozygous c.1640+1G>A founder mutation in ALS2. Three affected siblings from one family exhibit generalized dystonia which has not been previously described in families with IAHSP and has only been reported in three unrelated consanguineous families with JALS/ALS2. We report the oldest individuals with IAHSP to date and provide evidence that these patients survive well into their late 40s with preserved cognition and normal eye movements. Our study delineates the phenotypic spectrum of IAHSP and ALS2-related disorders and provides valuable insights into the natural disease course

Determination of susceptible areas to water erosion in the Hervi watershed

In order to protect soil and water resources should be identified erodible areas of watersheds, to be able to prevent land degradation and to control erosion in the form of soil conservation planning or watershed management. Therefore, the present study aimed to classification and delineation of susceptible areas to water erosion in the Hervi watershed using Hjulstrom curve, has been conducted. Increasing of accuracy, speed and facility of spatial achievement, using GIS technology, are advantages of the present study. In this study, were separated 10 sub-watersheds based on the feeding levels of streams. Spatial variability of soil properties in sub-watersheds, such as texture and the mean diameter size of the particles using hydrometer method were measured; also the maximum potential velocity of outlet in sub-watersheds based on the characteristics of each sub-watershed were calculated. Then, status of erosion and sediment in watersheds and sub-watersheds was studied using Hjulstrom curve (based on the mean diameter size of sediment particles and the maximum potential velocity of outlet), and was comparatively classified in term of erodibility. Finally, delineation map of susceptible regions to water erosion in the study area were obtained. The results revealed that the upstream and side areas of the watershed including: Sub-watershed No.4 (8.94% of the land), has very high erodibility, and Sub-watersheds No.1 and No.9 (36.94% of the land) have high erodibility. These areas are steep and often devoid of vegetation or have poor vegetation (such as poor pastures and rain-fed farming); so, it is necessary a proper strategy to prevent further erosion