259 research outputs found

    Multidisciplinary Tumor Boards - Right way forward in Cancer Management

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    Multidisciplinary Tumor Boards - Right way forward in Cancer Management

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    Consumer Innovativeness Leading to Innovation Adoption

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    With the changing trends in this world, innovative economy is the emerging idea that is vital for the economies, countries and organizations to grow and sustain. Innovation is the key to success and the innovators need to be influenced for adoption. For that reason, there is need of market analysis if consumers are ready for adopting the innovations that are offered to them, do they possess the necessary traits to understand the benefits of innovation in their lifestyles. This insight has given an opportunity to this research for analyzing the consumer market empirically for the traits that are necessary for the adoption of innovation. This study it further identify the market segment that are inclined possess the trait of innovativeness higher than the others. A survey questionnaire was adopted from literature; data was collected from almost 481 consumers belonging to Karachi from the age bracket of 15 to 54. The factor analysis, correlation, regression and 2SLS method was applied; results showed that consumer innovativeness is strongly influenced by personality traits such as intelligence, rationality and self-efficacy and socialization by interconnectedness, cosmopoliteness and subjective norm. The study reveals the insight that consumers are ready to adopt the innovation and possess the trait of innovativeness that has the capabilities to intellectually and rationally evaluate the innovative offering. Keywords: Consumer innovativeness, Innovation adoption, smart phone

    A review of environmental and occupational exposure to xylene and its health concerns

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    Xylene is a cyclic hydrocarbon, and an environmental pollutant. It is also used in dyes, paints, polishes, medical technology and different industries as a solvent. Xylene easily vaporizes and divides by sunlight into other harmless chemicals. The aim of the present review is to collect the evidence of the xylene toxicity, related to non-cancerous health hazards, as well as to provide possible effective measurement to minimize its risk ratio. For current study a bibliographic search of more than 250 peer-reviewed papers in scientific data including PubMed, and Google Scholar about xylene was done. But approximately 130 peer-reviewed papers relevant to xylene were included (Figure 1). All scientific data was reviewed with key words of “xylene toxicity”, “xylene toxic health effects”, “environmental volatile organic compounds”, “human exposure to xylene”, “xylene poisoning in laboratory workers”, “effects of xylene along with other hydrocarbons”, “neurotoxicity of selected hydrocarbons”, and “toxic effects of particular xylene isomers in animals”. According to these studies, xylene is released into the atmosphere as fugitive emissions from petrochemical industries, fire, cigarette, from different vehicles. Short term exposure to mixed xylene or their individual isomers result in irritation of the nose, eyes and throat subsequently leading toward neurological, gastrointestinal and reproductive harmful effects. In addition long term exposure to xylene may cause hazardous effects on respiratory system, central nervous system, cardiovascular system, and renal system. The health concerns of xylene are well documented in animals and human. It is important to improve health policies, launch xylene related health and toxicity awareness campaigns, to get rid of its dangerous outcomes. Chronic diseases have become a threat to human globally, with special prominence in regions, where xylene is used with other chemicals (benzene, toluene etc.) especially in petroleum and rubber industry. The mechanism of toxicity and interactions with endocrine system should be followed up which is the main threat to human health

    A Model of Open Source Software-Based Product Line Development

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    Software Product Line (SPL) and Open Source Software (OSS) have emerged as successful modes of developing software. There is an increased interest in developing suitable approaches for combining the promised advantages of SPL andOSS. Researchers and practitioners have been emphasizing the need of exploiting the ever growing repositories ofOSScomponents for developing SPLs. However, there is no conceptual model for guiding the process of developing OSS-based SPLs. In this paper, we propose a model for developing software product line using open source software. This paper identifies and elaborates the essential phases and activities of the proposed model of developing OSS-based SPLs. This model emphasizes the vital role of software architecture and asserts that software architectures ofOSScan be exploited to establish a SPL. To demonstrate this, we have evaluated Eclipse’s architecture for its potential to support different flavors of a system

    Bioactive flavanoids from Glycosmis arborea

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    BACKGROUND: Glycosmis is a genus of evergreen glabrous shrub and distributed all over India. It possesses various medicinal properties and is used in indigenous medicine for cough, rheumatism, anemia, and jaundice. Glycosmis arborea is a rich source of alkaloids, terpenoids, coumarins, as well as flavonoids. RESULTS: The chemical investigation of methanol fraction of the leaves of G. arborea led to the isolation of one new flavone C-glycoside along with three known flavanoids, named as 5,7-dihydroxy-2-[4-hydroxy-3-(methoxy methyl) phenyl]-6-C-β-d-glucopyranosyl flavone (4), 5,7,4(′)-trihydroxy-3(′)-methoxy flavone (1), 5,4(′)-dihydroxy-3(′)-methoxy-7-O-β-d-glucupyranosyl flavanone (2), and 5,4(′)-dihydroxy-3(′)-methoxy-7-O-(α-l-rhamnosyl-(1‴→6‴)-β-d-glucopyranosyl) flavanone (3), respectively. The structures of all compounds were elucidated with the help of nuclear magnetic resonance spectrometry. Pure compounds and fractions were evaluated for pest antifeedant and antimicrobial activity. CONCLUSION: Four compounds were isolated from the leaves of G. arborea. Among them, compound 4 showed significant antimicrobial activity
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