0014 : Implications of myocardial reperfusion on survival in women versus men with acute myocardial infarction undergoing primary coronary intervention

BackgroundThe in hospital mortality rate after myocardial infarction is higher among women than men. PCI is recommended treatment for ST -segment elevation myocardial infarction (STEMI) in patients of both genders. It is used in women without a clear demonstration of their efficiency in this population. It is only extrapolations of studies enrolling a large majority of males (more than 85%). It is very important to improve our therapeutic stratégies in women, to perform dedicated studies.AimOf our study was to compare clinical and angiographic features in men and women and to determine wether gender influenced in – hospital prognosis of primary percutaneous coronary intervention.MethodsWe conducted a retrospective study including 282 patients admitted in the University hospital of Blida (Alegria). Between April 2009 and January 2011. All these patients had an ST segment elevation myocardial infarction and underwent primary PCI within 12 hours after symptom onset.ResultsOur population counted 239men and 43women. Females were significantly older (p<0.05). They had a higher prevalence of diabetes 32.6% (P<0.05), hypertension 55.8% (P=0.01), dyslipemia16.3% (P<0.05). They were more likely to consult late (Mean time from symptom onset was 299.7±93.9min in women vs 296±97.9mn in men (p<0.001). In our study, angiographic success was achieved in 76.7% of the cases in women and in 92.1% of the cases in men (p=0.005). The in hospital mortality rate was 7% in women and 5% in men (p=NS).ConclusionThere is no gender descrepancy in – hospital mortality in patients who undergo emergency PCI for treatment of STEMI. These data suggest that gender should not affect the decision to offer PCI but further gender specific studies are warranted