Evaluation of the improvement of the clinical symptoms and spirometric indices in asthmatic patients having different treatments

Abstract: since most of the asthmatic patients do not use the proper medicine to control their persistent symptoms, we decided to accomplish a study to find out the relation between the treatment, clinical symptoms and spirometric indices in asthmatic patients. this study is a cross-sectional study on 150 patients suffering from persistent moderate asthma admitted to naghavi and beheshti hospital. They have less than three attacks weekly. After recording of their clinical symptoms (dyspenea, cough, wheezing and nocturnal) and spirometric indices (FEV1, FEV1/FVC, FVC) twice with intervals of 3-6 months, they were divided into three groups. The first group was treated with salbutamol inhaler, the second with salbutamol and floxitide and the third one withsalmeterol and floxitide. Then all the data was evaluated through SPSS program. the group treated with salmeterol and floxitide inhaler showed the greatest remission in coughing (%80.4), Dyspnea (%77.8), Wheezing (%77.8) and nocturnal symptoms (80%). In comparison to the other groups, the variance was statistically significant. In the study, most variances in FEV1and FEV1/FVC were observed in the receiver group of salbutamol, and most FVC variances were in receiver group of salbutamol-floxitid. Statistically there was no significant variance among the groups. This study showes the most clinical remission in the receiver group of salmeterol and floxitide, and spirometric indices are not sufficient to control the level of patients' treatment so that clinical symptoms are more valuable