648 research outputs found
Prevalence of Takotsubo Syndrome among Patients Admitted to an Emergency Department
Article信州医学雑誌 70(1) : 39-46(2022)departmental bulletin pape
Dogs as Sentinels for Human Infection with Japanese Encephalitis Virus
Because serosurveys of Japanese encephalitis virus (JEV) among wild animals and pigs may not accurately reflect risk for humans in urban/residential areas, we examined seroprevalence among dogs and cats. We found that JEV-infected mosquitoes have spread throughout Japan and that dogs, but not cats, might be good sentinels for monitoring JEV infection in urban/residential areas
Biochemical analyses of lipids deposited on silicone hydrogel lenses
AbstractPurposeThis study was performed to determine the levels of lipids deposited on in vivo worn silicone hydrogel lenses.MethodsThree silicone hydrogel materials, galyfilcon A, senofilcon A, and asmofilcon A, were worn for 2 weeks by 35 normal subjects. Total lipid deposition was determined by the sulfo-phospho-vanillin reaction. Cholesterol was estimated by a colorimetric probe through enzymatic oxidation. Phospholipid level was estimated by determining phosphorus with ammonium molybdate through enzymatic digestion.ResultsThe total lipid content recovered from galyfilcon A, senofilcon A, and asmofilcon A was 32.9 ± 33.8, 42.1 ± 14.0, and 36.6 ± 31.9 μg/lens, respectively. The cholesterol content recovered from galyfilcon A, senofilcon A, and asmofilcon A was 26.2 ± 26.9, 28.6 ± 19.4, and 31.1 ± 21.1 μg/lens, respectively. There were no statistically significant differences in total lipids and cholesterol among the contact lens types. However, the quantity of phospholipid recovered from the asmofilcon A (7.0 ± 5.5 μg/lens) lenses was significantly higher than from galyfilcon A (1.1 ± 0.8 μg/lens) and senofilcon A (2.4 ± 0.8 mg/lens) lenses (p < 0.05, Mann-Whitney test).ConclusionsThe quantity of total lipid and cholesterol deposited on the 3 silicone hydrogel lenses tested did not differ. However, there were significant differences in the amounts of phospholipid deposited among the 3 silicone hydrogel lenses, of which clinical significance should be explored in the future study
Multifrequency VLBI Observations of the Broad Absorption Line Quasar J1020+4320: Recently Restarted Jet Activity?
This paper reports very-long-baseline interferometry observations of the
radio-loud broad absorption line (BAL) quasar J1020+4320 at 1.7, 2.3, 6.7, and
8.4 GHz using the Japanese VLBI network (JVN) and European VLBI network (EVN).
The radio morphology is compact with a size of ~10 pc. The convex radio
spectrum is stable over the last decade; an observed peak frequency of 3.2 GHz
is equivalent to 9.5 GHz in the rest frame, suggesting an age of the order of
~100 years as a radio source, according to an observed correlation between
linear size and peak frequency of compact steep spectrum (CSS) and giga-hertz
peaked spectrum (GPS) radio sources. A low-frequency radio excess suggests
relic of past jet activity. J1020+4320 may be one of the quasars with recurrent
and short-lived jet activity during a BAL-outflowing phase.Comment: 7 pages, 2 figures, 2 tables, accepted for publication in PAS
Antibiotic prescription for outpatients with influenza and subsequent hospitalisation: a cohort study using insurance data
Background
Whether prophylactic administration of antibiotics to patients with influenza reduces the hospitalisation risk is unknown. We aimed to examine the association between antibiotic prescription in outpatients with influenza infection and subsequent hospitalisation.
Methods
We conducted a cohort study using health insurance records of Japanese clinic and hospital visits between 2012 and 2016. Participants were outpatients (age, 0–74 years) with confirmed influenza infection who were prescribed anti-influenza medicine. The primary outcomes were the hospitalisation risk from all causes and pneumonia and the duration of hospitalisation due to pneumonia.
Results
We analysed 903,104 outpatient records with 2469 hospitalisations. The risk of hospitalisation was greater in outpatients prescribed anti-influenza medicine plus antibiotics (0.31% for all causes and 0.18% for pneumonia) than in those prescribed anti-influenza medicine only (0.27% and 0.17%, respectively). However, the risk of hospitalisation was significantly lower in patients prescribed peramivir and antibiotics than in those prescribed peramivir only. Patients who received add-on antibiotics had a significantly longer hospital stay (4.12 days) than those who received anti-influenza medicine only (3.77 days). In all age groups, the hospitalisation risk from pneumonia tended to be greater in those who received antibiotics than in those prescribed anti-influenza medicine only. However, among older patients (65–74 years), those provided add-on antibiotics had an average 5.24-day shorter hospitalisation due to pneumonia than those provided anti-influenza medicine only (not significant).
Conclusions
In outpatient cases of influenza, patients who are prescribed antibiotics added to antiviral medicines have a higher risk of hospitalisation and longer duration of hospitalisation due to pneumonia
ANALYSIS OF STEP-VELOCITY DEPENDENCES OF CARBON CONCENTRATION IN c- AND m-PLANE GaN HOMOEPITAXIAL LAYERS
Reported step-velocity dependences of carbon concentration in c- and m-plane GaN homoepitaxial layers were successfully reproduced based on a step-edge segregation model with the following assumptions: 1) the diffusion coefficient of carbon in GaN is 2×10^-13 cm^2/s (@ 1000℃−1100℃); 2) the length of time before the carbon concentration at the step-edge site reaches its equilibrium value is sufficiently shorter than the meantime until a carbon atom incorporated at the kink site moves through the step-edge site to the surface site
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