9 research outputs found
Three-dimensional study of radiation symmetrization in some indirectly driven heavy ion ICF targets
Promoting-mode free formalism for excited state radiationless decay process with Duschinsky rotation effect
Reproducibility of nocturnal blood pressure fall in early phases of untreated essential hypertension: a prospective observational study
Lesões dermatolĂłgicas em pacientes infectados pelo vĂrus linfotrĂłpico humano de cĂ©lulas T do tipo 1 (HTLV-1) Dermatologic lesions in patients infected with the human T-cell lymphotropic vĂrus type 1 (HTLV-1)
O vĂrus linfotrĂłpico humano de cĂ©lulas T do tipo 1 (HTLV-1) Ă© o primeiro retrovĂrus isolado do ser humano. Descreveu-se, em pouco tempo, o seu papel etiolĂłgico em algumas doenças, com destaque para a leucemia/linfoma de cĂ©lulas T do adulto (ATLL), a mielopatia associada ao HTLV-1/paraparesia espástica tropical (HAM/TSP) e a uveĂte associada ao HTLV-1 (HAU). Na dĂ©cada de 90, o HTLV-1 foi associado a eczema grave da infância, conhecido como dermatite infecciosa (DI). Desde entĂŁo, diversos outros tipos de lesões cutâneas tĂŞm sido observados em pacientes infectados pelo HTLV-1, em especial, nos doentes de HAM/TSP ou de ATLL. PorĂ©m, mesmo portadores assintomáticos do vĂrus apresentam doenças dermatolĂłgicas. Excetuando-se a dermatite infecciosa, nĂŁo há lesĂŁo da pele especĂfica da infecção pelo HTLV-1. Aqui, os autores apresentam as principais lesões dermatolĂłgicas descritas em pacientes infectados pelo HTLV-1, destacando o valor epidemiolĂłgico e clĂnico desses achados.<br>Human T-cell Lymphotropic vĂrus type I (HTLV-1) was the first human retrovĂrus described. Some time after its discovery a group of diseases were related to this vĂrus, such as, adult T-cell leukemia lymphoma (ATLL), HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV-1 associated uveitis (HAU). In the nineties, HTLV-1 was associated to a severe eczema of children, called infective dermatitis (ID). Since then, several other skin manifestations have been observed in HTLV-1-infected individuals, particularly in patients with ATLL or HAM/TSP. However, according to some reports, dermatologic lesions are also common in asymptomatic HTLV-1 carriers. Besides ID, all other skin lesions reported are nonspecific. The aim of this review is to outline the dermatologic manifestations reported in HTLV-1 infected patients, emphasizing the clinical and epidemiological value of these findings