Enhancing the student experience through the creation and use of authentic and accessible conflict scenarios

Authentic conflict scenarios are an essential basis for learning activities and assessment tasks in the conflict management and resolution field. Authentic scenarios allow students to apply theories and skills to realistic situations, enhancing their learning experiences and workforce readiness. However, finding suitable conflict scenarios for use in teaching and learning is challenging due to a) Confidentiality: limiting the types of conflicts that can be used; b) Evolving resources: conflicts already in the public eye are often complex and continue to evolve which requires a great deal of effort by educators to update content, restricts the diversity of resources available, and makes it difficult to impartially present all aspects of a conflict in an engaging way; and c) Lack of engaging resources: fictitious scenarios are often presented in written text only, failing to provide interactive and engaging resources. In 2016, the James Cook University (JCU) Conflict Management and Resolution (CMR) Program, with the support of a Student Services and Amenities Fee (SSAF) grant, created an authentic and digitally accessible conflict scenario designed to address these challenges and deliver improved learning experiences for postgraduate conflict management and resolution students and educators. This article discusses the value of authentic scenarios to improve postgraduate student experiences and career outcomes in the dispute resolution field, the approach taken by the JCU CMR Program to develop the scenario and presents findings from preliminary feedback from students' and educators' experience using the conflict scenario in postgraduate course work

Characterization of the behavior of carotenoids from pitanga (Eugenia uniflora) and buriti (Mauritia flexuosa) during microemulsion production and in a dynamic gastrointestinal system

Uncommon tropical fruits are emerging as raw-material for new food products with health benefits. This work aimed at formulating and processing microemulsions from pitanga (Eugenia uniflora) and buriti (Mauritia flexuosa) fruits, since they are very rich in carotenoids (particularly lycopene and -carotene), in order to encapsulate and increase carotenoids bioaccessibility. Pitanga and buriti microemulsions were produced by applying a direct processing (high-speed homogenization at 15,000 rpm and ultrasound with 20 kHz probe at 40% amplitude) of the whole pulp together with surfactant (Tween 80 or Whey Protein Isolate at 2%) and corn oil (5%). All treatments (HSHUS for 04, 40, 44, 48 minmin) applied were able to increase the amount of carotenoid released. However, the processing also decreased the total amount of carotenoids in the whole pulp of studied fruits. The impact of processing during microemulsion production was not severe. The overall data suggest that the presence of surfactant and oil during processing may protect the carotenoids in fruits and microemulsions. Final recovery of total carotenoids, after passing the samples through a dynamic gastrointestinal system that simulates the human digestion, was higher for microemulsions than for whole pulps. High losses of total carotenoids in buriti and -carotene and lycopene in pitanga occurred during jejunum and ileum phases. The present work confirms that it is possible to increase -carotene and lycopene bioaccessibility from fruits by directly processing microemulsions (p<0.01).This work was supported by the São Paulo Research Foundation—FAPESP through research funding [Grant #2015/15507-9] and Ph.D. scholarship for Paulo Berni [Grant #2014/15119-6] and a Research Internships Abroad (BEPE) support [Grant #2016/13355-0]. The author Ana C. Pinheiro is recipient of a fellowship from the Portuguese Foundation for Science and Technology (FCT) [Grant SFRH/BPD/101181/2014]info:eu-repo/semantics/publishedVersio

Post-translational protein modifications in malaria parasites

Post-translational modifications play crucial parts in regulating protein function and thereby control several fundamental aspects of eukaryotic biology, including cell signalling, protein trafficking, epigenetic control of gene expression, cell–cell interactions, and cell proliferation and differentiation. In this Review, we discuss protein modifications that have been shown to have a key role in malaria parasite biology and pathogenesis. We focus on phosphorylation, acetylation, methylation and lipidation. We provide an overview of the biological significance of these modifications and discuss prospects and progress in antimalarial drug discovery based on the inhibition of the enzymes that mediate these modifications