Comparison of imaging biomarkers for Alzheimer\u27s disease: amyloid imaging with [(18) F]florbetapir positron emission tomography and magnetic resonance imaging voxel-based analysis for entorhinal cortex atrophy.

We compared amyloid positron emission tomography (PET) and magnetic resonance imaging (MRI) in subjects clinically diagnosed with Alzheimer\u27s disease (AD), mild cognitive impairment (MCI), and older healthy controls (OHC) in order to test how these imaging biomarkers represent cognitive decline in AD

Differentiation Between Dementia With Lewy Bodies And Alzheimer’s Disease Using Voxel-Based Morphometry Of Structural MRI:AMulticenter Study

Dementia with Lewy bodies (DLB) is one of the main etiologies of neurodegenerative dementia after Alzheimer’s disease (AD).1 Distinguishing DLB from AD is difficult because of their overlapping clinical and pathological features.2–4 Patients with clinically defined DLB may also have AD-type pathological changes as well as the characteristic Lewy bodies. However, the differential diagnosis is particularly important because DLB respond better to cholinesterase inhibitors but are sensitive to neuroleptics, which cause worsening of clinical status