81 research outputs found

    An Examination of the non-gaming nightlife entertainment sector of Las Vegas resort-casinos

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    This paper provides an overview of the non-gaming nightlife entertainment sector of Las Vegas resort-casinos. Three qualitative interviews with executives of The Mandalay Bay Resort & Casino, The Monte Carlo Las Vegas Resort and Casino, and The Mirage Las Vegas were conducted to examine their perceptions and needs in the industry. This paper examines the impact the current economic recession is having on the Las Vegas nightlife and also reveals what types of questions resort-casino operators want to know about their customer. This exploratory research is a useful preliminary step that helps ensure that a more rigorous, more conclusive future study will not begin with an inadequate understanding of the nature of the problem

    Water Intake Reduces the Noradrenaline Release in the Median Preoptic Nucleus Area Caused by Angiotensin II Injected into the Subfornical Oragn in the Rat

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    The present study was carried out to investigate the role of noradrenergic systems in the median preoptic nucleus (MnPO) in the drinking response caused by microinjection of angiotensin II (ANG II) into the subfornical organ (SFO) in the awake rat. Extracellular levels of noradrenaline (NA) in the region of theMnPO were monitored with in vivo microdialysis methods. Injections of ANG II (10^ M,50 nl) into the SFO significantly increased NA release in the MnPO area. The increase in the NA release induced by the ANG II injection was significantly reduced by water ingestion. In urethane-anesthetized rats, injections of ANG II into the SFO produced an elevation in mean arterial pressure (M.A.P.). Intravenous infusions of metaraminol (5μg), on the other hand, slightly suppressed the release of NA in the MnPO area that accompanied an elevation in M.A.P. These results suggest that the noradrenergic system in the MnPO may be involved in the dipsogenic response induced by ANG II acting at the SFO

    Temperature Dependence of 2 H Nuclear Quadrupole Interaction in Very Short Hydrogen Bonds in Some Organic Acidic Salt Crystals

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    The 2 H nuclear quadrupole interaction parameters, 2 and , are closely related to the shape of the potential energy surface at hydrogen bonds and depend sensitively on their geometry. We measured the temperature dependence of the 2 H NMR spectra of the crystalline acidic salts KDCO 3 , KD acetylenedicarboxylate, RbD acetylenedicarboxylate, and KD maleate, which contain very short O-D O type hydrogen bonds. The temperature coefficient decreases with increase in the O O distance in the hydrogen bond. Ab inito molecular orbital calculations of the electric field gradient tensor based on the temperature dependent structure of each crystal indicate that thermal expansion of the hydrogen bond geometry is not responsible for this tendency. Ab initio calculations also predict that a fictitious off center shift of the hydrogen position in a symmetric hydrogen bond causes very hig

    Successful Management of Fungal Keratitis by Alternaria alternata Complicating Mooren’s Ulcer

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    Mooren’s ulcer is an idiopathic peripheral ulcerative keratitis whose pathogenesis is thought to be due to an autoimmune reaction. The first-line treatment for Mooren’s ulcer is the use of topical steroids, which can be difficult to discontinue. The 76-year-old patient in this case was receiving topical steroids for bilateral Mooren’s ulcer and developed a feathery corneal infiltration and perforation in the left eye. On suspicion of a fungal keratitis complication, we started topical voriconazole treatment and performed lamellar keratoplasty. Topical betamethasone was continued twice a day. The identified causative fungus was Alternaria alternata, which is known to be susceptible to voriconazole. The minimum inhibitory concentration of voriconazole was later proven to be 0.5 μg/mL. After 3 months of treatment, the residual feathery infiltration disappeared and the left vision recovered to 0.7. In this case, topical voriconazole was effective, and the eye was successfully treated with continuing topical steroids. Fungal species identification and antifungal susceptibility test proved helpful for symptom management
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