Frequency and Distribution of Candida Species from Denture Wearers

Species of Candida were isolated from 100 denture wearers, who were examined for grade of denture stomatitis, degree of denture plaque accumulation and other clinical features. Candida albicans was the dominant species isolated from denture surfaces followed by Torulopsis glabrata and Candida tropicalis. Statistical analysis of the results revealed close relationships between the grade of denture stomatitis and the degree of denture plaque accumulation or the fungal concentration on the denture surface, and also between the degree of denture plaque accumulation and fungal concentration on the denture surface. Furthermore, the grade of denture stomatitis correlated with the period of denture wearing but not with the patient's age. The fungal concentration on denture surface also correlated with the patient's age and the period of denture wearing

A Simplified Culture for the Diagnosis of Denture Stomatitis

The relationship between the clinical features of denture stomatitis and the number of Candida colonies determined by swabs from the palatal mucosa has been proved to be close. In daily practice, if the number of Candida organisms can be assessed present without both difficulty and need for special equipment, it might be of benefit. Therefore, a simplified culture has been developed for the diagnosis of denture stomatitis in the dental office, which is based on the acid-producing capacity of Candida species and is displayed in color changes. The coefficient of correlation between the culture reaction and the clinical assessment of denture stomatitis was r=-0.64 ~ -0.86. It has also been helpful in instructing patients about denture cleanliness.Stomastat® (Sankin Industry Co. Ltd., Osaka, Japan) and Candida Yellow Medium® (Fujiseiyakukogyo Co. Ltd., Tokyo, Japan) on the market are based on this research

Experimental and Chcal Study of Dose-Reducing Effect of Normal Tissues in Interstitial Radiotherapy of the Tongue Carcinom

本論文の要旨は平成3年6月の第24回広島大学歯学会総会において発表した

Studies on Candida in Denture Plaque (Part 1) The Relationship between Candida in Denture Plaque and Denture Stomatitis (Part 2) Removal of Candida adhered to Denture Acrylic Resin by Yeast Lytic Enzyme

広島大学歯学雑誌, 第16巻,第2号, 242-249, 1984 (昭和59年) 広島大学歯学雑誌, 第16巻,第2号, 250-259, 1984 (昭和59年)広島大学(Hiroshima University)博士(医学)Medicinedoctora

骨形成不全症患者の補綴処置

Osteogenesis imperfecta is a syndrome of interest to dentists because dentinogenesis imperfecta is frequently associated with not only bone disease but also tooth disease. Specifically, these patients usually have many dental problems such as 1) high incidence of tooth fracture, enamel chipping and cracking, 2) high caries activity, 3) inability or difficulty of endodontic treatment, 4) masticatory disturbance and 5) esthetic dissatisfaction.　　This paper presents a case report of a patient with osteogenesis imperfecta and dentinogenesis imperfecta who was provided prosthetic treatment, including endodontic treatment of the obliterated teeth

Clinical Effect of Infusion Therapy in Combination with Local Antimycotic Drugs on Acute Pseudomembraneous Candidiasis Induced by Removable Dentures

Denture stomatitis is often observed in the denture-bearing mucosa. Candida albicans and related species are now believed to play a major role as a pathogenic factor in denture stomatitis. If systemic predisposing factors are present, denture stomatitis will sometimes develop into acute pseudomembraneous candidiasis. In acute pseudomembraneous candidiasis, the patients cannot take foods, and dehydration often occurs. This vicious cycle is the most important cause of increase in the growth of Candida species. Therefore, in order to improve the patient's physical condition, infusion therapy will be the first choice of treatment. The purpose of this study was to investigate the clinical effect of infusion therapy in combination with local antimycotic drugs on this type of candidiasis. We observed 4 cases of acute pseudomembraneous candidiasis induced by removable dentures and tried to treat these patients with infusion therapy (5% dextrose in lactatedRinger's solution) and local antimycotic drugs (Nystatin ointment or 1 % Miconazole nitrate cream). The acute inflammatory symptoms were significantly decreased by this therapy. The result of this study indicated that infusion therapy in combination with local antimycotic drugs was clinicaly effective on acute pseudomembraneous candidiasis induced by Candida-induced denture stomatitis

炎症・ホルモン・環境ホルモンがプラーク微生物に及ぼす影響 : in vitroにおける分子生物学的検討

研究期間:平成11-12年度 ; 研究種目:基盤研究B2 ; 課題番号:11470415原著には既発表論文の別刷を含む