3,323 research outputs found
Emigrant and immigrant small-island profiles
This study examines a global sample of forty small islands less than three million in population,
14 characterized by chronic immigration and 26 typified by chronic emigration. It constructs
separate socio-economic and demographic profiles of the two island groups using means
difference analysis across twenty-two indicators. The paper concludes that the immigrant islands
are significantly more economically and socially advanced and demographically mature than
their emigrant counterparts. It argues indirectly that the source of the formerâs affluence is their
greater degree of postwar diversification, especially towards international tourism, offshore
banking and export manufacturing.peer-reviewe
Voluntary, Chronic Dehydration in Adolescent American Football Players
The purpose of the study was to determine whether voluntary acute or chronic dehydration occurs in a male adolescent athletic population during twicea- day American football practice sessions. We conclude that participants will voluntarily rehydrate themselves between practice sessions and will begin to acclimate within three to four days
Criminal Thinking, Psychiatric Symptoms, and Recovery Attitudes Among Community Mental Health Patients
Research suggests it is important to consider criminogenic needs among individuals with severe mental illness. This study aimed to determine the severity of criminal thinking in community-based clinical samples, understand the association between criminal thinking and psychiatric and criminal justice outcomes, and compare these associations between consumers enrolled in Assertive Community Treatment (ACT) and Forensic Assertive Community Treatment (FACT) programs. Participants (N = 234) were male and female consumers enrolled in ACT and FACT programs in five states. Results revealed no significant differences in criminal thinking when comparing participants by program type or history of criminal justice involvement. There were significant positive relations between general criminal thinking and psychiatric symptomatology and the number of lifetime arrests, a negative association between recovery attitudes and general criminal thinking, and ACT participants reported a greater number of lifetime psychiatric hospitalizations than FACT participants. Result implications are discussed with specific reference to treatment programming
Inter-Platform comparability of microarrays in acute lymphoblastic leukemia
BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy and has been the poster-child for improved therapeutics in cancer, with life time disease-free survival (LTDFS) rates improving from <10% in 1970 to >80% today. There are numerous known genetic prognostic variables in ALL, which include T cell ALL, the hyperdiploid karyotype and the translocations: t(12;21)[TEL-AML1], t(4;11)[MLL-AF4], t(9;22)[BCR-ABL], and t(1;19)[E2A-PBX]. ALL has been studied at the molecular level through expression profiling resulting in un-validated expression correlates of these prognostic indices. To date, the great wealth of expression data, which has been generated in disparate institutions, representing an extremely large cohort of samples has not been combined to validate any of these analyses. The majority of this data has been generated on the Affymetrix platform, potentially making data integration and validation on independent sample sets a possibility. Unfortunately, because the array platform has been evolving over the past several years the arrays themselves have different probe sets, making direct comparisons difficult. To test the comparability between different array platforms, we have accumulated all Affymetrix ALL array data that is available in the public domain, as well as two sets of cDNA array data. In addition, we have supplemented this data pool by profiling additional diagnostic pediatric ALL samples in our lab. Lists of genes that are differentially expressed in the six major subclasses of ALL have previously been reported in the literature as possible predictors of the subclass. RESULTS: We validated the predictability of these gene lists on all of the independent datasets accumulated from various labs and generated on various array platforms, by blindly distinguishing the prognostic genetic variables of ALL. Cross-generation array validation was used successfully with high sensitivity and high specificity of gene predictors for prognostic variables. We have also been able to validate the gene predictors with high accuracy using an independent dataset generated on cDNA arrays. CONCLUSION: Interarray comparisons such as this one will further enhance the ability to integrate data from several generations of microarray experiments and will help to break down barriers to the assimilation of existing datasets into a comprehensive data pool
Conservation practice could benefit from routine testing and publication of management outcomes
Effective conservation requires a step change in the way practitioners can contribute to science and
can have access to research outputs. The journal Conservation Evidence was established in 2004 to
help practitioners surmount several obstacles they face when attempting to document the effects of
their conservation actions scientifically. It is easily and freely accessible online. It is free to publish in
and it enables global communication of the effects of practical trials and experiments, which are
virtually impossible to get published in most scientific journals. The driving force behind
Conservation Evidence is the need to generate and share scientific information about the effects of
interventions
Preventing Teen Relationship Abuse and Sexual Assault through Bystander Training: Intervention Outcomes for School Personnel
The purpose of the current study was to examine the impact of exposure to Bringing in the BystanderâHigh School Curriculum (BITB-HSC) on school personnel, which included a seven session classroom curriculum for ninth through twelfth graders (student curriculum), a bystander training workshop for school personnel (school personnel workshop), and reading materials (handout). We examined how exposure to these various BITB-HSC intervention components was associated with school personnelâs knowledge and bystander efïŹcacy, intentions, and barriers speciïŹc to student relationship abuse (RA) and sexual assault (SA). Participants were 488 school personnel from 12 high schools in upper New England who completed the 4-month follow-up survey that assessed for intervention exposure (284 participants completed both the baseline and follow-up survey). Whereas 53% of participants were exposed to no intervention components, the other half of the sample were exposed to a combination of intervention components. Higher baseline knowledge and reactive bystander intentions were associated with subsequent exposure to both the student curriculum and the handout, and fewer barriers to bystander action predicted exposure to the school personnel workshop. Exposure to the school personnel workshop, student curriculum, and handout was associated with subsequent greater knowledge, exposure to the student curriculum predicted reactive bystander intentions, and exposure to the handout predicted higher reactive bystander intentions and bystander efïŹcacy. Findings suggest that despite challenges with engagement, exposure to the BITB-HSC components may be a useful tool in improving school personnelâs responses to RA and SA among high school students
Masters of the Universe: Bid Rigging by Private Equity Firms in Multibillion Dollar LBOs
In the first successful case of its kind, a class action alleging widespread collusion in the market for leveraged buyouts, some of the worldâs largest private equity firms settled Dahl v. Bain Capital Partners, LLC for 12 billion.
The use of empirical economic analysis in antitrust litigation is now de rigueur. Courts expect it, and litigants have an array of econometricians available who understand both how to work with data and antitrust doctrine. In âordinaryâ commodities price fixing cases, plaintiffs and defendants are expected to engage experts who gather transaction data and apply regression theory and other economic analyses to contest whether it is possible to demonstrate injury, impact, and damages. Dahl was not an ordinary case in that it involved neither a commodity nor a sellersâ cartel. Instead, it involved a buyersâ cartel which, Plaintiffs alleged, conspired to drive down the price of a number of unique, large LBOs during the mid-2000s. Additionally, the case was notable because of the Plaintiffsâ decision to use the auction theory to demonstrate the existence of antitrust violations and the extent of damage
Mnemonic Monitoring in Anosognosia for Memory Loss
Objective: Anosognosia, or unawareness, for memory loss has been proposed to underlie cognitive functions such as memory and executive function. However, there is an inconsistent association between these constructs. Recent studies have shown that compromise ongoing self-monitoring of oneâs memory associates with anosognosia for memory loss. Yet to date it is unclear which memory monitoring mechanisms are impaired in these patients. In this study, we examined the extent to which temporal monitoring or orbitofrontal reality filtering (e.g., ability to monitor the temporal relevance of a memory) and source monitoring (e.g., the ability to distinguish which memories stem from internal as opposed to external sources) are associated with awareness of memory deficits.
Methods: A total of 35 patients (M=69 years; M=14 years of education) with memory difficulties following a stroke were recruited from outpatient clinics. Patients were assessed with measures of self-awareness of memory difficulties, cognitive abilities and two experimental paradigms assessing source and temporal monitoring.
Results and conclusion: Results showed that patients unaware of their memory difficulties were more likely to externalize the source of their memories. Specifically, those unaware of their deficits were more likely to assign an external source to memories that were internally produced (e.g., imagined). No differences were observed in relation to temporal monitoring between patients aware and unaware of their deficits. This study informs current theoretical models of self-awareness of memory loss. Future studies should attempt to replicate these findings and explore different memory monitoring mechanisms in relation to anosognosia for memory loss
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