14 research outputs found
Cross-Sector Review of Drivers and Available 3Rs Approaches for Acute Systemic Toxicity Testing
Get PDFAcute systemic toxicity studies are carried out in many sectors in which synthetic chemicals are manufactured or used and are among the most criticized of all toxicology tests on both scientific and ethical grounds. A review of the drivers for acute toxicity testing within the pharmaceutical industry led to a paradigm shift whereby in vivo acute toxicity data are no longer routinely required in advance of human clinical trials. Based on this experience, the following review was undertaken to identify (1) regulatory and scientific drivers for acute toxicity testing in other industrial sectors, (2) activities aimed at replacing, reducing, or refining the use of animals, and (3) recommendations for future work in this area
the multiplier effect of the development of forest park tourism on employment creation in china
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Analysis of Design Elements and Barriers to Link the Emission Trading Systems between the Republic of Korea and China
Full text linkA load-carrier perspective examination on the change of ecological environment carrying capacity during urbanization process in China
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Use of food waste, fish waste and food processing waste for China's aquaculture industry: Needs and challenge
Full text linkDetermining suitable selection cutting intensities based on long-term observations on aboveground forest carbon, growth, and stand structure in Changbai Mountain, Northeast China
Full text linkEffects of substituting alfalfa hay for concentrate on energy utilization and feeding cost of crossbred Simmental male calves in Gansu Province, China
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