Study on the effect of fuel additive on PFI gasoline engine performance and emissions

With increasingly stringent emission and fuel consumption regulations, fuel additives have been proved to have a huge role in energy conservation and emission reduction, a new type of fuel additive based on nitroparaffin has received worldwide attention. An experimental study was conducted with the aim of developing an understanding of the fuel additive’s effect on a 1.5L naturally aspirated PFI gasoline engine’s power performance, fuel economy, emissions and cylinder cleanliness. The results show that when fueled with fuel additive, engine power increased at full load condition. The commonly used working condition’s average fuel consumption decreased by 4.5% at fuel consumption contour map. For pollutant emissions, unburned hydrocarbons (HC), smoke (filter smoke number, FSN) decreased significantly, slightly higher nitrogen oxides (NOx) compared with no fuel additive. Furthermore, the use of fuel additive has a positive effect on elimination of carbon deposit in the cylinder

Study on the effects of nitro-based fuel additive on diesel engine performance and emissions

Through adding nitro-based fuel additive into diesel fuel,the influences of additive on engine performance, gaseous emission, particle number concentration and exhaust smoke were studied on a test bench. Meanwhile, the functioning mechanism and combustion characteristics were studied through constant volume combustion vessel. The system is composed of high pressure common rail fuel injection system, high pressure constant volume combustion vessel, high speed camera, data synchronization and acquisition system. The maximum diesel injection pressure is 160 MPa, and it can be heated to 1000 K under the back pressure of 3 MPa. According to the research results, adding fuel additive can decrease both exhaust smoke and exhaust temperature of engine for european steady state cycle(ESC). Moreover, The fuel additive improved the engine’s power slightly and expanded the economic fuel consumption working area. The minimum fuel consumption rate was reduced from 204.6g/kWh to 202.2g/kWh, and the highest fuel saving rate was about 2%. After adding MAZ, the mass of the recycled particles can be reduced by about 15%,and the average smoke intensity of most operating points showed a downward trend, with a maximum drop of 55%, the NOx weighted emissions of the whole cycle decreased by more than 2%. After adding nitro-based fuel additive, the ignition delay and flame lift-off length became longer in the combustion process, but the duration of combustion was shorter, which are in accordance with chemical reaction kinetics analysis

Profiling, clinicopathological correlation and functional validation of specific long non-coding RNAs for hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) is one of the most prevalent and aggressive malignancies worldwide. Studies seeking to advance the overall understanding of lncRNA profiling in HCC remain rare. Methods The transcriptomic profiling of 12 HCC tissues and paired adjacent normal tissues was determined using high-throughput RNA sequencing. Fifty differentially expressed mRNAs (DEGs) and lncRNAs (DELs) were validated in 21 paired HCC tissues via quantitative real-time PCR. The correlation between the expression of DELs and various clinicopathological characteristics was analyzed using Student’s t-test or linear regression. Co-expression networks between DEGs and DELs were constructed through Pearson correlation co-efficient and enrichment analysis. Validation of DELs’ functions including proliferation and migration was performed via loss-of-function RNAi assays. Results In this study, we identified 439 DEGs and 214 DELs, respectively, in HCC. Furthermore, we revealed that multiple DELs, including NONHSAT003823, NONHSAT056213, NONHSAT015386 and especially NONHSAT122051, were remarkably correlated with tumor cell differentiation, portal vein tumor thrombosis, and serum or tissue alpha fetoprotein levels. In addition, the co-expression network analysis between DEGs and DELs showed that DELs were involved with metabolic, cell cycle, chemical carcinogenesis, and complement and coagulation cascade-related pathways. The silencing of the endogenous level of NONHSAT122051 or NONHSAT003826 could significantly attenuate the mobility of both SK-HEP-1 and SMMC-7721 HCC cells. Conclusion These findings not only add knowledge to the understanding of genome-wide transcriptional evaluation of HCC but also provide promising targets for the future diagnosis and treatment of HCC