5,903 research outputs found
Switching off the magnetic exchange coupling by quantum resonances
We clarify the role of quantum-well states in magnetic trilayer systems from
majority carrier in the ferromagnetic and all carriers in the antiferromagnetic
configurations. In addition to numerical and analytic calculations, heuristic
pictures are provided to explain effects of a capping layer and side-layer
modulation in recent experiments. This immediately offers answers to two
unexplained subtle findings in experiments and band-structure calculations,
individually. Furthermore, it allows a more flexible tuning of or even turning
off the interlayer exchange coupling.Comment: 5 pages, 5 figure
Sequential change in olfaction and (non) motor symptoms: the difference between anosmia and non-anosmia in Parkinson’s disease
IntroductionHyposmia is a common prodrome in patients with Parkinson’s disease (PD). This study investigates whether olfactory changes in PD differ according to the degree of olfactory dysfunction and whether there are changes in motor and non-motor symptoms.MethodsThe 129 subjects with PD were divided into two groups: anosmia and non-anosmia. All cases were reassessed within 1–3 years after the initial assessment. The assessment included the MDS-Unified PD Rating Scale (MDS-UPDRS), the University of Pennsylvania Smell Identification Test (UPSIT), Beck’s Depression Inventory-II (BDI-II), Montreal Cognitive Assessment (MoCA), and equivalence dose of daily levodopa (LEDD). The generalized estimating equation (GEE) model with an exchangeable correlation structure was used to analyze the change in baseline and follow-up tracking and the disparity in change between these two groups.ResultsThe anosmia group was older and had a longer disease duration than the non-anosmia group. There was a significant decrease in UPSIT after follow-up in the non-anosmia group (β = −3.62, p < 0.001) and a significant difference in the change between the two groups (group-by-time effect, β = 4.03, p < 0.001). In the third part of the UPDRS motor scores, there was a tendency to increase the score in the non-anosmia group compared to the anosmia group (group-by-time effect, β = −4.2, p < 0.038). There was no significant difference in the group-by-time effect for UPDRS total score, LEDD, BDI-II, and MoCA scores.DiscussionIn conclusion, this study found that olfactory sensation may still regress in PD with a shorter disease course without anosmia, but it remains stable in the anosmia group. Such a decline in olfaction may not be related to cognitive status but may be associated with motor progression
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