1,535 research outputs found
Novel CMOS RFIC Layout Generation with Concurrent Device Placement and Fixed-Length Microstrip Routing
With advancing process technologies and booming IoT markets, millimeter-wave
CMOS RFICs have been widely developed in re- cent years. Since the performance
of CMOS RFICs is very sensi- tive to the precision of the layout, precise
placement of devices and precisely matched microstrip lengths to given values
have been a labor-intensive and time-consuming task, and thus become a major
bottleneck for time to market. This paper introduces a progressive
integer-linear-programming-based method to gener- ate high-quality RFIC layouts
satisfying very stringent routing requirements of microstrip lines, including
spacing/non-crossing rules, precise length, and bend number minimization,
within a given layout area. The resulting RFIC layouts excel in both per-
formance and area with much fewer bends compared with the simulation-tuning
based manual layout, while the layout gener- ation time is significantly
reduced from weeks to half an hour.Comment: ACM/IEEE Design Automation Conference (DAC), 201
DreaMo: Articulated 3D Reconstruction From A Single Casual Video
Articulated 3D reconstruction has valuable applications in various domains,
yet it remains costly and demands intensive work from domain experts. Recent
advancements in template-free learning methods show promising results with
monocular videos. Nevertheless, these approaches necessitate a comprehensive
coverage of all viewpoints of the subject in the input video, thus limiting
their applicability to casually captured videos from online sources. In this
work, we study articulated 3D shape reconstruction from a single and casually
captured internet video, where the subject's view coverage is incomplete. We
propose DreaMo that jointly performs shape reconstruction while solving the
challenging low-coverage regions with view-conditioned diffusion prior and
several tailored regularizations. In addition, we introduce a skeleton
generation strategy to create human-interpretable skeletons from the learned
neural bones and skinning weights. We conduct our study on a self-collected
internet video collection characterized by incomplete view coverage. DreaMo
shows promising quality in novel-view rendering, detailed articulated shape
reconstruction, and skeleton generation. Extensive qualitative and quantitative
studies validate the efficacy of each proposed component, and show existing
methods are unable to solve correct geometry due to the incomplete view
coverage.Comment: Project page: https://ttaoretw.github.io/DreaMo
Relationship between overweight and obesity and insufficient micronutrient intake: a nationwide study in Taiwan
The aim of the present study is to examine whether overweight or obese people in Taiwan have an inadequate intake of selected micronutrients. A population-based study was conducted using data from the Nutrition and Health Survey in Taiwan (NAHSIT) 2013β2016. We evaluated fourteen nutrient intakes using the 24 h dietary recall method. The dietary reference intake (DRI) adherence was estimated by the prevalence of participants whose intake was lower than the recommended dietary allowance (RDA) or adequate intakes (AIs) for selected micronutrients. Body mass index (BMI) β₯ 27 kg/m2 and waist circumference (WC), with men having WC β₯ 90 cm or women having WC β₯ 80 cm, were defined as obesity. A total of 3075 participants aged 19 years and above were included. After adjusting for confounders, we found that obese women have a lower DRI adherence of vitamin C (odds ratio (OR) 0β
73, 95 % confidence interval (CI) 0β
56, 0β
95) and magnesium (OR 0β
72, 95 % CI 0β
54, 0β
95), compared with normal-weight women. Obese men have a higher DRI adherence of vitamin B3 (OR 1β
70, 95 % CI 1β
29, 2β
23), iron (OR 1β
46, 95 % CI 1β
06, 2β
00) and zinc (OR 1β
41, 95 % CI 1β
07, 1β
85), compared with normal-weight men. Similar findings were found using WC to define obesity. We conclude that obese women may have insufficient intakes of vitamin A, vitamin C and magnesium
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Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding
Retroviruses favor target-DNA (tDNA) distortion and particular bases at sites of integration, but the mechanism underlying HIV-1 selectivity is unknown. Crystal structures revealed a network of prototype foamy virus (PFV) integrase residues that distort tDNA: Ala188 and Arg329 interact with tDNA bases, while Arg362 contacts the phosphodiester backbone. HIV-1 integrase residues Ser119, Arg231, and Lys258 were identified here as analogs of PFV integrase residues Ala188, Arg329 and Arg362, respectively. Thirteen integrase mutations were analyzed for effects on integrase activity in vitro and during virus infection, yielding a total of 1610 unique HIV-1 integration sites. Purine (R)/pyrimidine (Y) dinucleotide sequence analysis revealed HIV-1 prefers the tDNA signature (0)RYXRY(4), which accordingly favors overlapping flexible dinucleotides at the center of the integration site. Consistent with roles for Arg231 and Lys258 in sequence specific and non-specific binding, respectively, the R231E mutation altered integration site nucleotide preferences while K258E had no effect. S119A and S119T integrase mutations significantly altered base preferences at positions β3 and 7 from the site of viral DNA joining. The S119A preference moreover mimicked wild-type PFV selectivity at these positions. We conclude that HIV-1 IN residue Ser119 and PFV IN residue Ala188 contact analogous tDNA bases to effect virus integration
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