BioPepDB: an integrated data platform for food-derived bioactive peptides

<p>Food-derived bioactive peptides play critical roles in regulating most biological processes and have considerable biological, medical and industrial importance. However, a large number of active peptides data, including sequence, function, source, commercial product information, references and other information are poorly integrated. BioPepDB is a searchable database of food-derived bioactive peptides and their related articles, including more than four thousand bioactive peptide entries. Moreover, BioPepDB provides modules of prediction and hydrolysis-simulation for discovering novel peptides. It can serve as a reference database to investigate the function of different bioactive peptides. BioPepDB is available at <a href="http://bis.zju.edu.cn/biopepdbr/" target="_blank">http://bis.zju.edu.cn/biopepdbr/</a>. The web page utilises Apache, PHP5 and MySQL to provide the user interface for accessing the database and predict novel peptides. The database itself is operated on a specialised server.</p

Shore hardness value of 60Co γ-irradiated PMMA impregnated with two media.

Shore hardness value of 60Co γ-irradiated PMMA impregnated with two media.</p

Relative molecular mass differential distribution curves of PMMA.

Relative molecular mass differential distribution curves of PMMA.</p

Evolution of transmittance with various 60Co γ irradiation doses for PMMA.

Evolution of transmittance with various 60Co γ irradiation doses for PMMA.</p

Improved Performances of LiNi_0.8Co_0.15Al_0.05O₂ Material Employing NaAlO₂ as a New Aluminum Source

To prepare a high-performance LiNi_0.8Co_0.15Al_0.05O₂ material (LNCA) for Li-ion batteries, a new aluminum source, NaAlO₂, is employed in the coprecipitation step for the first time, and the effect of aluminum sources on the performances is systematically investigated. Different from the traditional preparation process using Al­(NO₃)₃ as the aluminum source, the preparation process of the Ni_0.8Co_0.15Al_0.05(OH)_2.05 precursor from NaAlO₂ is a hydrolysis process, during which the fast precipitation of Al³⁺ and the formation of a flocculent precipitate can be effectively avoided. As expected, stoichiometric LNCA with uniform element distribution, low cation mixing and well-ordered layered structure is obtained from NaAlO₂, which is designed as LNCA-NaAlO₂. The characterization and electrochemical measurements show that LNCA-NaAlO₂ exhibits significantly improved performances (such as tap density, initial discharge capacity and volumetric energy density, rate performance, cycle performance, electrochemical stability, microstructure stability, and storage stability) compared to the performances of those prepared from Al­(NO₃)₃ (LNCA-Al­(NO₃)₃), indicating that it is an effective strategy to preparing high-performance LNCA employing NaAlO₂ as the aluminum source

In Situ Fabrication of CoS and NiS Nanomaterials Anchored on Reduced Graphene Oxide for Reversible Lithium Storage

CoS and NiS nanomaterials anchored on reduced graphene oxide (rGO) sheets, synthesized via combination of hydrothermal with sulfidation process, are studied as high-capacity anode materials for the reversible lithium storage. The obtained CoS nanofibers and NiS nanoparticles are uniformly dispersed on rGO sheets without aggregation, forming the sheet-on-sheet composite structure. Such nanoarchitecture can not only facilitate ion/electron transport along the interfaces, but also effectively prevent metal-sulfide nanomaterials aggregation during the lithium reactions. Both the rGO-supported CoS nanofibers (NFs) and NiS nanoparticles (NPs) show superior lithium storage performance. In particular, the CoS NFs-rGO electrodes deliver the discharge capacity as high as 939 mA h g^–1 after the 100th cycle at 100 mA g^–1 with Coulombic efficiency above 98%. This strategy for construction of such composite structure can also synthesize other metal-sulfide-rGO nanomaterials for high-capacity lithium-ion batteries

Data_Sheet_1_Simultaneous determination of twelve mycotoxins in edible oil, soy sauce and bean sauce by PRiME HLB solid phase extraction combined with HPLC-Orbitrap HRMS.xlsx

A solid phase extraction-high-performance liquid chromatography-tandem Orbitrap high resolution mass spectrometry (HPLC-Orbitrap HRMS) method was established for the determination of 12 mycotoxins (ochratoxin A, ochratoxin B, aflatoxin B1, aflatoxin B2, aflatoxin G1, aflatoxin G2, HT-2 toxin, sterigmatocystin, diacetoxysciroenol, penicillic acid, mycophenolic acid, and citreoviridin) in edible oil, soy sauce, and bean sauce. Samples were extracted by 80:20 (v:v) acetonitrile-water solution, purified by PRiME HLB column, separated by aQ C18 column with mobile phase consisting of 0.5 mmol/L ammonium acetate-0.1% formic acid aqueous solution and methanol. The results showed that the limits of detection (LODs) and limits of quantification (LOQs) of 12 mycotoxins were 0.12–1.2 μg/L and 0.40–4.0 μg/L, respectively. The determination coefficients of 12 mycotoxins in the range of 0.20–100 μg/L were > 0.998. The average recoveries in soy sauce and bean sauce were 78.4–106.8%, and the relative standard deviations (RSDs) were 1.2–9.7% under three levels, including LOQ, 2× LOQ and 10 × LOQ. The average recoveries in edible oil were 78.3–115.6%, and the precision RSD (n = 6) was 0.9–8.6%. A total of 24 edible oils, soy sauce and bean sauce samples were analyzed by this method. AFB1, AFB2, sterigmatocystin and mycophenolic acid were detected in several samples at concentrations ranging from 1.0 to 22.1 μg/kg. The method is simple, sensitive, and rapid and can be used for screening and quantitative analysis of mycotoxin contamination in edible oil, soy sauce, and bean sauce.</p