Impact of Body Mass Index on Survival of Pancreatic Cancer Patients in Japan

The impact of body mass index (BMI) on postoperative survival in Japanese patients with pancreatic cancer is unclear. We examined the relationship between preoperative BMI and the prognosis of Japanese patients who underwent surgery for pancreatic cancer to determine whether BMI affects these patients’ prognosis. Of the patients who underwent pancreatectomy between January 2004 and August 2015 at our institution, 246 were pathologically diagnosed with pancreatic tubular adenocarcinoma; the cancer was located in the pancreatic head (n=161) and in the body and tail (n=85). We classified the patients by BMI: underweight (n=22), normal weight (n=190), and overweight/obese (n=34) groups. We retrospectively analyzed medical records for patient characteristics, lesion location, disease stage, postoperative complications, chemotherapy, and prognosis. Lesion location, disease stage, postoperative complications, and chemotherapy were not significantly different among the BMI groups. The median survival times were as follows (days): all patients, 686; underweight, 485; normal weight, 694; and overweight/obese, 839. In a multivariate analysis, after adjusting for competing risk factors, low BMI was associated with an increased risk of death (normal weight: HR 0.58, p=0.038; overweight/obese: HR 0.54, p=0.059). High BMI was not found to be a postoperative factor for poor prognosis in Japanese pancreatic cancer patients

Author Correction: Fish proliferation and rare-earth deposition by topographically induced upwelling at the late Eocene cooling event (Scientific Reports, (2020), 10, 1, (9896), 10.1038/s41598-020-66835-8)

金沢大学理工研究域地球社会基盤学系An amendment to this paper has been published and can be accessed via a link at the top of the paper. © 2020, The Author(s)

Fish proliferation and rare-earth deposition by topographically induced upwelling at the late Eocene cooling event

金沢大学理工研究域地球社会基盤学系The deep-sea clay that covers wide areas of the pelagic ocean bottom provides key information about open-ocean environments but lacks age-diagnostic calcareous or siliceous microfossils. The marine osmium isotope record has varied in response to environmental changes and can therefore be a useful stratigraphic marker. In this study, we used osmium isotope ratios to determine the depositional ages of pelagic clays extraordinarily rich in fish debris. Much fish debris was deposited in the western North and central South Pacific sites roughly 34.4 million years ago, concurrent with a late Eocene event, a temporal expansion of Antarctic ice preceding the Eocene–Oligocene climate transition. The enhanced northward flow of bottom water formed around Antarctica probably caused upwelling of deep-ocean nutrients at topographic highs and stimulated biological productivity that resulted in the proliferation of fish in pelagic realms. The abundant fish debris is now a highly concentrated source of industrially critical rare-earth elements. © 2020, The Author(s)

Model validation using induced tensile stress during cracking process measured with desiccation stress tests

Tensile stress is internally induced when soil shrinkage due to desiccation is restricted, and cracks occur when the induced tensile stress reaches tensile strength. Various numerical models have been proposed to predict crack initiation; however, the validity of the computed internal stresses during the cracking process has not been assessed, although the internal stresses directly influence the crack initiation. The aim of this study was to demonstrate the effectiveness of a laboratory-based desiccation stress test, which measures the induced tensile stress until crack initiation. Desiccation stress tests were performed on unsaturated sandy soil with two different water contents. The measured tensile stress until cracking was numerically simulated using a hypo-elastic model based on the skeleton stress considering the suction effects. The computed tensile stress was consistent with the measured values throughout the cracking process in both cases, with different initial water contents. Stress-based validation using the results of the desiccation stress test demonstrated that the proposed constitutive model yields reliable estimations of the internal tensile stress in unsaturated soils until crack initiation

Automated Detection of Hydrothermal Emission Signatures From Multibeam Echo Sounder Images Using Deep Learning

Seafloor massive sulfide deposits have attracted attention as a mineral resource, as they contain a wide variety of base, precious, and other valuable critical metals. Previous studies have shown that signatures of hydrothermal activity can be detected by a multibeam echo sounder (MBES), which would be beneficial for exploring sulfide deposits. Although detecting such signatures from acoustic images is currently performed by skilled humans, automating this process could lead to improved efficiency and cost effectiveness of exploration for the seafloor deposits. Herein, we attempted to establish a method for automated detection of MBES water column anomalies using deep learning models. First, we compared the “Mask R-CNN” and “YOLO-v5” detection model architectures, wherein YOLO-v5 yielded higher F1 scores. We then compared the number of training classes and found that models trained with two classes (signal and noise) exhibited superior performance compared with models trained with only one class (signal). Finally, we examined the number of trainable parameters and obtained the best model performance when the YOLO-v5l model with a large trainable parameters was used in the two-class training process. The best model had a precision of 0.928, a recall of 0.881, and an F1 score of 0.904. Moreover, this model achieved a low false alarm rate (less than 0.7%) and had a high detection speed (20−25 ms per frame), indicating that it can be applied in the field for automatic and real-time exploration of seafloor hydrothermal deposits

Rare‐Earth Elements in Deep‐Sea Sediments in the South Pacific Gyre: Source Materials and Resource Potentials

Abstract Deep‐sea sediments enriched in rare‐earth elements and yttrium (REY) plus scandium (Sc), termed “REY‐rich mud,” have attracted attention as a possible resource for these critical industrial elements. Examples have been reported from the western North Pacific, central Pacific, low‐latitude South Pacific, and eastern South Pacific. Although previous studies of pelagic clay have reported the existence of highly REY‐rich mud in the ultraoligotrophic South Pacific Gyre, neither the source materials nor the resource potentials for REY and Sc of the sediment have been quantified. We analyzed the major‐ and trace‐element contents of bulk sediments in Integrated Ocean Drilling Program Holes U1365A to U1370D, drilled in the South Pacific Gyre. The elemental relationships suggest that the enrichment in REY and Sc reflects the accumulation of biogenic Ca phosphate in an environment with low sedimentation rates as well as the tectonic transition of depositional environments from hydrothermally influenced sites near the mid‐ocean ridge to distal basins far from hydrothermal vents. The maximum total REY content of 4,662 ppm at Hole U1366C is the highest value yet reported from the South Pacific Ocean. Although the REY‐ and Sc‐enriched sediment layers of most cores from the South Pacific Gyre are located deeper beneath the seafloor than those elsewhere in the Pacific Ocean, Hole U1367B demonstrates large resource potentials (1.21 × 104 t/km2 of REY oxides and 102 t/km2 of Sc) in the uppermost 6.5‐m interval, making it the most promising site for REY and Sc yet found in the South Pacific Gyre