The influence of strange quarks on QCD phase diagram and chemical freeze-out: Results from the hadron resonance gas model

We confront the lattice results on QCD phase diagram for two and three flavors with the hadron resonance gas model. Taking into account the truncations in the Taylor-expansion of energy density $\epsilon$ done on the lattice at finite chemical potential $\mu$, we find that the hadron resonance gas model under the condition of constant $\epsilon$ describes very well the lattice phase diagram. We also calculate the chemical freeze-out curve according to the entropy density $s$. The $s$-values are taken from lattice QCD simulations with two and three flavors. We find that this condition is excellent in reproducing the experimentally estimated parameters of the chemical freeze-out.Comment: 5 pages, 3 figures and 1 table Talk given at VIIIth international conference on ''Strangeness in Quark Matter'' (SQM 2004), Cape Town, South Africa, Sep. 15-20 200

Entropy for Color Superconductivity in Quark Matter

We study a model for color superconductivity with both three colors and massless flavors including quark pairing. By using the Hamiltonian in the color-flavor basis we can calculate the quantum entropy. From this we are able to further investigate the phases of the color superconductor, for which we find a rather sharp transition to color superconductivity above a chemical potential around $290$MeV.Comment: 10 pages, 2 eps-figure

Conditions driving chemical freeze-out

We propose the entropy density as the thermodynamic condition driving best the chemical freeze-out in heavy-ion collisions. Taking its value from lattice calculations at zero chemical potential, we find that it is excellent in reproducing the experimentally estimated freeze-out parameters. The two characteristic endpoints in the freeze-out diagram are reproduced as well.Comment: 8 pages, 5 eps figure

The Effects of Quantum Entropy on the Bag Constant

The effects of quantum entropy on the bag constant are studied at low temperatures and small chemical potentials. The inclusion of the quantum entropy of the quarks in the equation of state provides the hadronic bag with an additional heat which causes a decrease in the effective latent heat inside the bag. We have considered two types of baryonic bags, $\Delta$ and $\Omega^-$. In both cases we have found that the bag constant without the quantum entropy almost does not change with the temperature and the quark chemical potential. The contribution from the quantum entropy to the equation of state clearly decreases the value of the bag constant.Comment: 7 pages, 2 figures (two parts each

The QCD phase diagram: A comparison of lattice and hadron resonance gas model calculations

We compare the lattice results on QCD phase diagram for two and three flavors with the hadron resonance gas model (HRGM) calculations. Lines of constant energy density $\epsilon$ have been determined at different baryo-chemical potentials $\mu_B$. For the strangeness chemical potentials $\mu_S$, we use two models. In one model, we explicitly set $\mu_S=0$ for all temperatures and baryo-chemical potentials. This assignment is used in lattice calculations. In the other model, $\mu_S$ is calculated in dependence on $T$ and $\mu_B$ according to the condition of vanishing strangeness. We also derive an analytical expression for the dependence of $T_c$ on $\mu_B/T$ by applying Taylor expansion of $\epsilon$. In both cases, we compare HRGM results on $T_c-\mu_B$ diagram with the lattice calculations. The agreement is excellent, especially when the trigonometric function of $\epsilon$ is truncated up to the same order as done in lattice simulations. For studying the efficiency of the truncated Taylor expansion, we calculate the radius of convergence. For zero- and second-order radii, the agreement with lattice is convincing. Furthermore, we make predictions for QCD phase diagram for non-truncated expressions and physical masses. These predictions are to be confirmed by heavy-ion experiments and future lattice calculations with very small lattice spacing and physical quark masses.Comment: 25 pages, 8 eps figure

Quantum Entanglement in Second-quantized Condensed Matter Systems

The entanglement between occupation-numbers of different single particle basis states depends on coupling between different single particle basis states in the second-quantized Hamiltonian. Thus in principle, interaction is not necessary for occupation-number entanglement to appear. However, in order to characterize quantum correlation caused by interaction, we use the eigenstates of the single-particle Hamiltonian as the single particle basis upon which the occupation-number entanglement is defined. Using the proper single particle basis, we discuss occupation-number entanglement in important eigenstates, especially ground states, of systems of many identical particles. The discussions on Fermi systems start with Fermi gas, Hatree-Fock approximation, and the electron-hole entanglement in excitations. The entanglement in a quantum Hall state is quantified as -fln f-(1-f)ln(1-f), where f is the proper fractional part of the filling factor. For BCS superconductivity, the entanglement is a function of the relative momentum wavefunction of the Cooper pair, and is thus directly related to the superconducting energy gap. For a spinless Bose system, entanglement does not appear in the Hatree-Gross-Pitaevskii approximation, but becomes important in the Bogoliubov theory.Comment: 11 pages. Journal versio

Elliptic flow of electrons from heavy-flavor hadron decays in Au+Au collisions at sNN=\sqrt{s_{\rm NN}} = 200, 62.4, and 39 GeV

We present measurements of elliptic flow ($v_2$) of electrons from the decays of heavy-flavor hadrons ($e_{HF}$) by the STAR experiment. For Au+Au collisions at $\sqrt{s_{\rm NN}} =$ 200 GeV we report $v_2$, for transverse momentum ($p_T$) between 0.2 and 7 GeV/c using three methods: the event plane method ($v_{2}${EP}), two-particle correlations ($v_2${2}), and four-particle correlations ($v_2${4}). For Au+Au collisions at $\sqrt{s_{\rm NN}}$ = 62.4 and 39 GeV we report $v_2${2} for $p_T< 2$ GeV/c. $v_2${2} and $v_2${4} are non-zero at low and intermediate $p_T$ at 200 GeV, and $v_2${2} is consistent with zero at low $p_T$ at other energies. The $v_2${2} at the two lower beam energies is systematically lower than at $\sqrt{s_{\rm NN}} =$ 200 GeV for $p_T < 1$ GeV/c. This difference may suggest that charm quarks interact less strongly with the surrounding nuclear matter at those two lower energies compared to $\sqrt{s_{\rm NN}} = 200$ GeV.Comment: Version accepted by PR

International longitudinal registry of patients with atrial fibrillation and treated with rivaroxaban: RIVaroxaban Evaluation in Real life setting (RIVER)

Background Real-world data on non-vitamin K oral anticoagulants (NOACs) are essential in determining whether evidence from randomised controlled clinical trials translate into meaningful clinical benefits for patients in everyday practice. RIVER (RIVaroxaban Evaluation in Real life setting) is an ongoing international, prospective registry of patients with newly diagnosed non-valvular atrial fibrillation (NVAF) and at least one investigator-determined risk factor for stroke who received rivaroxaban as an initial treatment for the prevention of thromboembolic stroke. The aim of this paper is to describe the design of the RIVER registry and baseline characteristics of patients with newly diagnosed NVAF who received rivaroxaban as an initial treatment. Methods and results Between January 2014 and June 2017, RIVER investigators recruited 5072 patients at 309 centres in 17 countries. The aim was to enroll consecutive patients at sites where rivaroxaban was already routinely prescribed for stroke prevention. Each patient is being followed up prospectively for a minimum of 2-years. The registry will capture data on the rate and nature of all thromboembolic events (stroke / systemic embolism), bleeding complications, all-cause mortality and other major cardiovascular events as they occur. Data quality is assured through a combination of remote electronic monitoring and onsite monitoring (including source data verification in 10% of cases). Patients were mostly enrolled by cardiologists (n = 3776, 74.6%), by internal medicine specialists 14.2% (n = 718) and by primary care/general practice physicians 8.2% (n = 417). The mean (SD) age of the population was 69.5 (11.0) years, 44.3% were women. Mean (SD) CHADS2 score was 1.9 (1.2) and CHA2DS2-VASc scores was 3.2 (1.6). Almost all patients (98.5%) were prescribed with once daily dose of rivaroxaban, most commonly 20 mg (76.5%) and 15 mg (20.0%) as their initial treatment; 17.9% of patients received concomitant antiplatelet therapy. Most patients enrolled in RIVER met the recommended threshold for AC therapy (86.6% for 2012 ESC Guidelines, and 79.8% of patients according to 2016 ESC Guidelines). Conclusions The RIVER prospective registry will expand our knowledge of how rivaroxaban is prescribed in everyday practice and whether evidence from clinical trials can be translated to the broader cross-section of patients in the real world

Kinin B1 Receptor Enhances the Oxidative Stress in a Rat Model of Insulin Resistance: Outcome in Hypertension, Allodynia and Metabolic Complications

BACKGROUND: Kinin B(1) receptor (B(1)R) is induced by the oxidative stress in models of diabetes mellitus. This study aims at determining whether B(1)R activation could perpetuate the oxidative stress which leads to diabetic complications. METHODS AND FINDINGS: Young Sprague-Dawley rats were fed with 10% D-Glucose or tap water (controls) for 8-12 weeks. A selective B(1)R antagonist (SSR240612) was administered acutely (3-30 mg/kg) or daily for a period of 7 days (10 mg/kg) and the impact was measured on systolic blood pressure, allodynia, protein and/or mRNA B(1)R expression, aortic superoxide anion (O(2)(*-)) production and expression of superoxide dismutase (MnSOD) and catalase. SSR240612 reduced dose-dependently (3-30 mg/kg) high blood pressure in 12-week glucose-fed rats, but had no effect in controls. Eight-week glucose-fed rats exhibited insulin resistance (HOMA index), hypertension, tactile and cold allodynia and significant increases of plasma levels of glucose and insulin. This was associated with higher aortic levels of O(2)(*-), NADPH oxidase activity, MnSOD and catalase expression. All these abnormalities including B(1)R overexpression (spinal cord, aorta, liver and gastrocnemius muscle) were normalized by the prolonged treatment with SSR240612. The production of O(2)(*-) in the aorta of glucose-fed rats was also measured in the presence and absence of inhibitors (10-100 microM) of NADPH oxidase (apocynin), xanthine oxidase (allopurinol) or nitric oxide synthase (L-NAME) with and without Sar[D-Phe(8)]des-Arg(9)-BK (20 microM; B(1)R agonist). Data show that the greater aortic O(2)(*-) production induced by the B(1)R agonist was blocked only by apocynin. CONCLUSIONS: Activation of kinin B(1)R increased O(2)(*-) through the activation of NADPH oxidase in the vasculature. Prolonged blockade of B(1)R restored cardiovascular, sensory and metabolic abnormalities by reducing oxidative stress and B(1)R gene expression in this model