Study of the Barringer Refractor Plate Correlation Spectrometer as a remote sensing instrument

Barringer refractor plate correlation spectrometer as remote sensing instrument of pollutant gases in atmospher

Modeling and Characterization of Acute Stress under Dynamic Task Conditions

Stress can be defined as the mental, physical, and emotional response of humans to stressors encountered in their personal or professional environment. Stressors are introduced in various activities, especially those found in dynamic task conditions when multiple task requirements must be performed. Stress and stressors have been described as activators and inhibitors of human performance. The ability to manage high levels of acute stress is an important determinant of successful performance in any occupation. In situations where performance is critical, personnel must be prepared to operate successfully under hostile or extreme stress conditions; therefore training programs and engineered systems must be tailored to assist humans in fulfilling these demands. To effectively design appropriate training programs for these conditions, it is necessary to quantitatively describe stress. A series of theoretical stress models have been developed in previous research studies; however, these do not provide quantification of stress levels nor the impact on human performance. By modeling acute stress under dynamic task conditions, quantitative values for stress and its impact on performance can be assessed. Thus, this research was designed to develop a predictive model for acute stress as a function of human performance and task demand. Initially, a four factor two level experimental design (2 (Noise) x 2 (Temperature) x 2 (Time Awareness) x 2 (Workload)) was performed to identify reliable physiological, cognitive and behavioral responses to stress. Next, multivariate analysis of variance (n=108) tests were performed, which showed statistically significant differences for physiological, cognitive and behavioral responses. Finally, fuzzy set theory techniques were used to develop a comprehensive stress index model. Thus, the resulting stress index model was constructed using input on physiological, cognitive and behavioral responses to stressors as well as characteristics inherent to the type of task performed and personal factors that interact as mediators (competitiveness, motivation, coping technique and proneness to boredom). Through using this stress index model to quantify and characterize the affects of acute stress on human performance, these research findings can inform proper training protocols and help to redesign tasks and working conditions that are prone to create levels of acute stress that adversely affect human performance

Ternary and quaternary oxides of Bi, Sr, and Cu

Before the discovery of superconductivity in an oxide of Bi, Sr, and Cu, the system Bi-Sr-Cu-O had not been studied, although several solid phases had been identified in the two-component regions of the ternary system Bi2O3-SrO-CuO. The oxides Sr2CuO3, SrCu2O2, SrCuO2, and Bi2CuO4 were then well known and characterized, and the phase diagram of the binary system Bi2O3 -SrO had been established in the temperature range 620 to 1000 C. Besides nine solutions of compositions Bi(2-2x) Sr(x) O(3-2x) and different symmetries, this diagram includes three definite compounds of stoichiometries Bi(2)SrO4, Bi2Sr2O5, and Bi2Sr3O6 (x = 0.50, 0.67 and 0.75 respectively), only the second of which with known unit-cell of orthorhombic symmetry, dimensions (A) a = 14.293(2), b = 7.651(2), c = 6.172(1), and z = 4. The first superconducting oxide in the system Bi-Sr-Cu-O was initially formulated as Bi2Sr2Cu2O(7+x), with an orthorhombic unit-cell of parameters (A) a = 5.32, b = 26.6, c = 48.8. In a preliminary study the same oxide was formulated with half the copper content, Bi(2)Sr(2)CuO(6+x), and indexed its reflections assuming an orthorhombic unit-cell of dimensions (A) a = 5.390(2), b = 26.973(8), c = 24.69(4). Subsequent studies by diffraction techniques have confirmed the composition 2:2:1. A new family of oxygen-deficient perovskites, was characterized, after identifying by x ray diffraction the phases present in the products of thermal treatments of about 150 mixtures of analytical grade Bi2O3, Sr(OH)2-8H2O and CuO at different molar ratios. X ray diffraction data are presented for some other oxides of Bi and Sr, as well as for various quaternary oxides, among them an oxide of Bi, Sr, and Cu

Acidosis Is a Key Regulator of Osteoblast Ecto-Nucleotidase Pyrophosphatase/Phosphodiesterase 1 (NPP1) Expression and Activity

Previous work has shown that acidosis prevents bone nodule formation by osteoblasts in vitro by inhibiting mineralisation of the collagenous matrix. The ratio of phosphate (Pi) to pyrophosphate (PPi) in the bone microenvironment is a fundamental regulator of bone mineralisation. Both Pi and PPi, a potent inhibitor of mineralisation, are generated from extracellular nucleotides by the actions of ecto‐nucleotidases. This study investigated the expression and activity of ecto‐nucleotidases by osteoblasts under normal and acid conditions. We found that osteoblasts express mRNA for a number of ecto‐nucleotidases including NTPdase 1–6 (ecto‐nucleoside triphosphate diphosphohydrolase) and NPP1‐3 (ecto‐nucleotide pyrophosphatase/phosphodiesterase). The rank order of mRNA expression in differentiating rat osteoblasts (day 7) was Enpp1 > NTPdase 4 > NTPdase 6 > NTPdase 5 > alkaline phosphatase > ecto‐5‐nucleotidase > Enpp3 > NTPdase 1 > NTPdase 3 > Enpp2 > NTPdase 2. Acidosis (pH 6.9) upregulated NPP1 mRNA (2.8‐fold) and protein expression at all stages of osteoblast differentiation compared to physiological pH (pH 7.4); expression of other ecto‐nucleotidases was unaffected. Furthermore, total NPP activity was increased up to 53% in osteoblasts cultured in acid conditions (P < 0.001). Release of ATP, one of the key substrates for NPP1, from osteoblasts, was unaffected by acidosis. Further studies showed that mineralised bone formation by osteoblasts cultured from NPP1 knockout mice was increased compared with wildtypes (2.5‐fold, P < 0.001) and was partially resistant to the inhibitory effect of acidosis. These results indicate that increased NPP1 expression and activity might contribute to the decreased mineralisation observed when osteoblasts are exposed to acid conditions

Imaging the asymmetric dust shell around CI Cam with long baseline optical interferometry

We present the first high angular resolution observation of the B[e] star/X-ray transient object CI Cam, performed with the two-telescope Infrared Optical Telescope Array (IOTA), its upgraded three-telescope version (IOTA3T) and the Palomar Testbed Interferometer (PTI). Visibilities and closure phases were obtained using the IONIC-3 integrated optics beam combiner. CI Cam was observed in the near-infrared H and K spectral bands, wavelengths well suited to measure the size and study the geometry of the hot dust surrounding CI Cam. The analysis of the visibility data over an 8 year period from soon after the 1998 outburst to 2006 shows that the dust visibility has not changed over the years. The visibility data shows that CI Cam is elongated which confirms the disc-shape of the circumstellar environment and totally rules out the hypothesis of a spherical dust shell. Closure phase measurements show direct evidence of asymmetries in the circumstellar environment of CI Cam and we conclude that the dust surrounding CI Cam lies in an inhomogeneous disc seen at an angle. The near-infrared dust emission appears as an elliptical skewed Gaussian ring with a major axis a = 7.58 +/- 0.24 mas, an axis ratio r = 0.39 +/- 0.03 and a position angle theta = 35 +/- 2 deg.Comment: 9 pages, 5 figures, accepted MNRA

Retinitis pigmentosa and allied conditions today: a paradigm of translational research

Monogenic human retinal dystrophies are a group of disorders characterized by progressive loss of photoreceptor cells leading to visual handicap. Retinitis pigmentosa is a type of retinal dystrophy where degeneration of rod photoreceptors occurs at the early stages. At present, there are no available effective therapies to maintain or improve vision in patients affected with retinitis pigmentosa, but post-genomic studies are allowing the development of potential therapeutic approaches. This review summarizes current knowledge on genes that have been identified to be responsible for retinitis pigmentosa, the involvement of these genes in the different forms of the disorder, the role of the proteins encoded by these genes in retinal function, the utility of genotyping, and current efforts to develop novel therapies

A statistical evaluation of the sexual dimorphism of the acetabulum in an Iberian population

Sex estimation is essential for human identification within bioarchaeological and medico-legal contexts. Amongst the sexually dimorphic skeletal elements commonly utilised for this purpose, the pelvis is usually preferred because of its direct relationship with reproduction. Furthermore, the posterior part of the innominate bone has proven to have better preservation within degraded contexts. With the aim of investigating the potential of the vertical acetabular diameter as a sex marker, 668 documented individuals from three different Iberian skeletal collections were randomly divided into training and test samples and eventually analysed using different statistical approaches. Two traditional (Discriminant Function Analysis and Logistic Regression Analysis) and four Machine learning methodologies (Support Vector Classification, Decision Tree Classification, k Nearest Neighbour Classification, and Neural Networks) were performed and compared. Amongst these statistical modalities, Machine Learning methodologies yielded better accuracy outcomes, with DTC garnering highest accuracy percentages of 83.59% and 89.85% with the sex-pooled and female samples, respectively. With males, ANN yielded highest accuracy percentage of 87.70%, when compared to other statistical approaches. Higher accuracy obtained with ML, along with its minimal statistical assumptions, warrant these approaches to be increasingly utilised for further investigations involving sex estimation and human identification. In this line, the creation of a statistical platform with easier user interface can render such robust statistical modalities accessible to researchers and practitioners, effectively maximising its practical use. Future investigations should attempt to achieve this goal, alongside examining the influence of factors such as age, on the obtained accuracy outcomes

Shannon entropy and particle decays

We deploy Shannon's information entropy to the distribution of branching fractions in a particle decay. This serves to quantify how important a given new reported decay channel is, from the point of view of the information that it adds to the already known ones. Because the entropy is additive, one can subdivide the set of channels and discuss, for example, how much information the discovery of a new decay branching would add; or subdivide the decay distribution down to the level of individual quantum states (which can be quickly counted by the phase space). We illustrate the concept with some examples of experimentally known particle decay distributions.Comment: 12 pages, 18 plots; to appear in Nuclear Physics

Mid-infrared size survey of Young Stellar Objects: Description of Keck segment-tilting experiment and basic results

The mid-infrared properties of pre-planetary disks are sensitive to the temperature and flaring profiles of disks for the regions where planet formation is expected to occur. In order to constrain theories of planet formation, we have carried out a mid-infrared (wavelength 10.7 microns) size survey of young stellar objects using the segmented Keck telescope in a novel configuration. We introduced a customized pattern of tilts to individual mirror segments to allow efficient sparse-aperture interferometry, allowing full aperture synthesis imaging with higher calibration precision than traditional imaging. In contrast to previous surveys on smaller telescopes and with poorer calibration precision, we find most objects in our sample are partially resolved. Here we present the main observational results of our survey of 5 embedded massive protostars, 25 Herbig Ae/Be stars, 3 T Tauri stars, 1 FU Ori system, and 5 emission-line objects of uncertain classification. The observed mid-infrared sizes do not obey the size-luminosity relation found at near-infrared wavelengths and a companion paper will provide further modelling analysis of this sample. In addition, we report imaging results for a few of the most resolved objects, including complex emission around embedded massive protostars, the photoevaporating circumbinary disk around MWC 361A, and the subarcsecond binaries T Tau, FU Ori and MWC 1080.Comment: Accepted by Astrophysical Journal. 38 pages. 9 figure

First L-band Interferometric Observations of a Young Stellar Object: Probing the Circumstellar Environment of MWC 419

We present spatially-resolved K- and L-band spectra (at spectral resolution R = 230 and R = 60, respectively) of MWC 419, a Herbig Ae/Be star. The data were obtained simultaneously with a new configuration of the 85-m baseline Keck Interferometer. Our observations are sensitive to the radial distribution of temperature in the inner region of the disk of MWC 419. We fit the visibility data with both simple geometric and more physical disk models. The geometric models (uniform disk and Gaussian) show that the apparent size increases linearly with wavelength in the 2-4 microns wavelength region, suggesting that the disk is extended with a temperature gradient. A model having a power-law temperature gradient with radius simultaneously fits our interferometric measurements and the spectral energy distribution data from the literature. The slope of the power-law is close to that expected from an optically thick disk. Our spectrally dispersed interferometric measurements include the Br gamma emission line. The measured disk size at and around Br gamma suggests that emitting hydrogen gas is located inside (or within the inner regions) of the dust disk.Comment: Accepted for publication in Ap