Neomicin - čest kontaktni alergen

The incidence of allergic contact dermatitis from neomycin evaluated in relation to 1381 verified cases of allergic contact dermatitis showed a progressive increase (5.00,7.69,10.18%) over a three-year period (1990-1992). Sensitivity to neomycin was investigated with special reference to possible cross-reactions between neomycin and the allergens that are commonly used in the manufacture of cosmetic products. Contact sensitivity to neomycin was found to be present with the other diagnoses, such as atopic dermatitis, seborrhoeic dermatitis, hypostasic dermatitis and psoriasis vulgaris.Pratili smo učestalost kontaktnog alergijskog dermatitisa na neomicin u razdoblju od 1990. do 1992. godine (5,00%; 7,69%, 10,18%) s obzirom na 1381 verificiran kontaktni alergijski dermatitis. Istodobno je prikazan kontaktni alergijski dermatitis s pozitivitetom na neomicin u odnosu na alergene s kojima može imati unakrsne reakcije, a rabe se često u kozmetičkim pripravcima. Prikazali smo kontaktnu senzibilizaciju na neomicin i u drugih dermatoza u kojih se češće javlja: neurodermatitis, seboroički dermatitis, hipostazički dermatitis i vulgarna psorijaza

Kontaktna alergija i psorijaza

The study was conducted over a two-year period and included 48 psoriatic patients with palmar and plantar lesions and 61 psoriatic patients without palmar and plantar lesions who served as controls. The objective was to establish the incidence of contact sensitization and its importance as the causative factor in palmar and plantar psoriasis. The most frequent contact allergens were: nickel sulphate, mercapto mix, balsam of Peru, potassium dichromate, mercury mix and fragrance mix. Patch tests were positive in 41.7% psoriatics with palrnar-plantar psoriasis and in only 6.6% of psoriatics without palmar-plantar involvement. The study showed an increased incidence of contact allergy in patients with palmar-planter psoriasis.Istraživanje je provedeno tijekom dvije godine u skupini od 48 pacijenata s palmoplantarnim oblikom psorijaze i u kontrolnoj skupini od 61 pacijenta s psorijazom ali bez oštećenja na dlanovima ili stopalima. Cilj je bio utvrditi učestalost kontaktne senziibilizacije i njeno značenje kao uzročnog faktora u nastanku palmoplanlarne psorijaze. Najčešći kontaktni alergeni bili su nikalj sulfat, smjesa merkapto spojeva, peruvijanski balzam, kalijev bikromat, smjesa živinih spojeva i smjesa mirisa. Epikutani testovi bili su pozitivni u 41,7 % pacijenata s palmoplanlarnom psorijazom i samo u 6,6 % kontrolnih pacijenata. Istraživanje je pokazalo povećanu učestalost kontaktne alergije u pacijenata s palmoplantarnim oblikom psorijaze