555 research outputs found
Propuestas para la enseñanza del italiano en el aula: aprender traduciendo
Los últimos trabajos sobre adquisición de lenguas extranjeras y sobre la enseñanza a los no nativos en general han puesto de manifiesto que la traducción, desterrada del aula en muchas ocasiones, constituye un instrumento muy valioso en el proceso didáctico y en el dominio de los diferentes niveles lingüísticos. La aplicación de esta técnica facilita y mejora el análisis del funcionamiento de lenguas afines como el español y el italiano.The lastest research on foreign languages acquisition and teaching to non-native speakers in general has proved that translation, often ignored in the classroom, is a very valuable resource in the pedagogical process and in the mastering of the diverse language levels. The application of this technique facilitates and improves the analysis of the functions similar languages as Spanish and Italian
La gramática como componente de la competencia comunicativa
En los enfoques comunicativos el foco de interés se ha desviado de la competencia
gramatical a la competencia comunicativa, noción de gran envergadura que ha supuesto un
cambio tanto en las técnicas y procedimientos como en la concepción de la
enseñanza/aprendizaje de una lengua extranjer
Dance Generation by Sound Symbolic Words
This study introduces a novel approach to generate dance motions using
onomatopoeia as input, with the aim of enhancing creativity and diversity in
dance generation. Unlike text and music, onomatopoeia conveys rhythm and
meaning through abstract word expressions without constraints on expression and
without need for specialized knowledge. We adapt the AI Choreographer framework
and employ the Sakamoto system, a feature extraction method for onomatopoeia
focusing on phonemes and syllables. Additionally, we present a new dataset of
40 onomatopoeia-dance motion pairs collected through a user survey. Our results
demonstrate that the proposed method enables more intuitive dance generation
and can create dance motions using sound-symbolic words from a variety of
languages, including those without onomatopoeia. This highlights the potential
for diverse dance creation across different languages and cultures, accessible
to a wider audience. Qualitative samples from our model can be found at:
https://sites.google.com/view/onomatopoeia-dance/home/
TGF-βが誘導するEpithelial-Mesenchymal Transdifferentiation(EMT)における分化制御因子Idの役割
取得学位 : 博士(医学), 学位授与番号 : 医博甲第1647号, 学位授与年月日 : 平成16年9月30日, 学位授与大学 : 金沢大
シュウマツキ ガン ショウレイ ニオケル コウカルシウム ケッショウ ノ ケントウ
Hypercalcemia develops in patients with advanced cancer and severely deteriorates their quality of life. This study aimed to evaluate the influence of hypercalcemia on the clinical course of patients with end-stage cancer. This retrospective study included data on 253 patients who had cancer and died in the palliative care unit at Kondo-Naika Hospital in 2008 and 2009. Of these patients, 16(6.3%) developed hypercalcemia during hospitalization before death. These 16 patients included5patients with lung cancer ;4 with esophageal cancer ;2 with pancreatic cancer ; and1patient each with liver cancer, breast cancer, gall bladder cancer, renal cancer, or gastric cancer. The incidence of esophageal cancer in the patients with hypercalcemia was significantly higher than that in the patients who did not have hypercalcemia(p<0.01). Of the 16 patients with hypercalcemia,10had bone metastasis, whereas the other6patients had hypercalcemia even without bone metastasis. The main symptom of hypercalcemia was drowsiness in7patients, delirium in6patients, and general fatigue in 3patients. Fifteen patients were treated using bisphosphonates. After the hypercalcemia was detected, the 16patients survived for only a short time, with a mean survival time of 16.9 days. In particular, the mean survival time of 7 patients who did not respond to treatment for hypercalcemia was only 6.0days, and1patient with a calcium level of 19.1 mg/dl died the day after zoledronic acid hydrate therapy was initiated. Thus, hypercalcemia in patients with end-stage cancer seems to indicate extremely critical conditions with the worst prognosis
Propuestas para la enseñanza del italiano en el aula: aprender traduciendo
Los últimos trabajos sobre adquisición de lenguas extranjeras y sobre la enseñanza a los no nativos en general han puesto de manifiesto que la traducción, desterrada del aula en muchas ocasiones, constituye un instrumento muy valioso en el proceso didáctico y en el dominio de los diferentes niveles lingüísticos. La aplicación de esta técnica facilita y mejora el análisis del funcionamiento de lenguas afines como el español y el italiano
Two novel fungal negative-strand RNA viruses related to mymonaviruses and phenuiviruses in the shiitake mushroom (Lentinula edodes)
Abstract There is still limited information on the diversity of (−)ssRNA viruses that infect fungi. Here, we have discovered two novel (−)ssRNA mycoviruses in the shiitake mushroom (Lentinula edodes). The first virus has a monopartite RNA genome and relates to that of mymonaviruses (Mononegavirales), especially to Hubei rhabdo-like virus 4 from arthropods and thus designated as Lentinula edodes negative-strand RNA virus 1. The second virus has a putative bipartite RNA genome and is related to the recently discovered bipartite or tripartite phenui-like viruses (Bunyavirales) associated with plants and ticks, and designated as Lentinula edodes negative-strand RNA virus 2 (LeNSRV2). LeNSRV2 is likely the first segmented (−)ssRNA virus known to infect fungi. Its smaller RNA segment encodes a putative nucleocapsid and a plant MP-like protein using a potential ambisense coding strategy. These findings enhance our understanding of the diversity, evolution and spread of (−)ssRNA viruses in fungi
Peroxynitrite-induced hemolysis of human erythrocytes and its inhibition by antioxidants
AbstractIt was found that human erythrocytes underwent hemolysis when incubated with peroxynitrite at 37°C under air. The extent of hemolysis increased with increasing peroxynitrite concentration and decreasing hematocrit. The peroxynitrite-induced hemolysis was suppressed only partially by a radical scavenging antioxidant such as uric acid and Trolox, a water-soluble vitamin E analogue, but reduced glutathione, N-acetylcysteine and albumin efficiently inhibited the hemolysis. A selenium-containing organic compound, ebselen, also suppressed the hemolysis. On the other hand, nitric oxide and superoxide generated concomitantly from 3-morpholinosydnonimine (SIN-1) did not induce appreciable hemolysis, while it converted hemoglobin to methemoglobin extensively
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