Individual and mean±SD ¹⁸F-DPA-714 DVR values obtained for the 8 healthy controls and the 10 ALS patients and results of Mann-Whitney test.

<p>DVR: Distribution of volume ratios -SD: Standard deviation.</p><p>Mann-Whitney-test: comparison between HC subjects (n = 8) and ALS patients (n = 10).</p

Individual DVR values for the two motor cortex regions and the temporal cortex obtained for all subjects.

<p>These are the regions where statistically significant differences were observed between the two groups studied.</p

Parametric (DVR) 18F-DPA-714 images (axial, coronal and sagittal slices) obtained for a healthy volunteer and an ALS patient, respectively.

<p>Note the significant but normal 18F-DPA-714 uptake in nasal epithelium (a tissue rich in TSPO).</p