Whitefellas and wadjulas: anti-colonial constructions of the non-aboriginal self

In this thesis, I argue for anti-colonial constructions of the non-Aboriginal self. I take as my starting point that members of the invader/settler society in Australia must place them/ourselves in “an embodied awareness of ‘being in Indigenous sovereignty’” (Nicholl, 2004: 17) and name them/ourselves accordingly. An anti-colonial construction of non-Aboriginality formed within the locus of Aboriginal Sovereignty undermines the potency of ‘post-colonial’ processes of identity formation, which privilege the colonialist centre, and the concomitant marginalised position of Indigenous people. Thus, an anti-colonial construction of non-Aboriginality constitutes a radical recentring for processes of identity construction within invader/settler societies. This work responds to critical whiteness studies and post-colonial discourses of ‘belonging’. I acknowledge both whiteness studies and work on invader/settler belongings have gained traction in recent years as a means to problematise the whiteness of the settler/invader group and the legitimacy of their/our belongings. However, I argue they continue to operate within colonialist paradigms and perpetuate (neo)colonial power relations. In this thesis, I argue anti-colonial constructions of non-Aboriginality are constructed in dialogue with Aboriginal people. I conceive non-Aboriginality as a political identity that rejects ‘race’ and ‘colour’ as markers for identity. ‘Non-Aboriginality’ enables members of invader/settler societies to articulate support for Aboriginal Sovereignty and Aboriginal claims for social justice and human rights

Capturing the Harm: Defining Tax Loss For Use in Federal Sentencing

The United States Sentencing Guidelines have set forth the system by which tax offenders are punished for violating the federal income tax laws. This Article explores the various methods that the appellate courts have used to define tax loss under the United States Sentencing Guidelines for purposes of sentencing enhancement for tax related offenses. It discusses the concept of tax loss for federal sentencing purposes, including the guideline provisions that drive the tax offender\u27s offense level and ultimate guideline imprisonment range. It explores major circuit decisions which interpreted the proper implementation of the guideline sentencing factors. Finally, it examines issues that remain unresolved and critiques some of the positions and methods that the reviewing courts have taken with respect to issues discussed in this article

A nonparametric penalized likelihood approach to density estimation of space–time point patterns

In this work, we consider space-time point processes and study their continuous space-time evolution. We propose an innovative nonparametric methodology to estimate the unknown space-time density of the point pattern, or, equivalently, to estimate the intensity of an inhomogeneous space-time Poisson point process. The presented approach combines maximum likelihood estimation with roughness penalties, based on differential operators, defined over the spatial and temporal domains of interest. We first establish some important theoretical properties of the considered estimator, including its consistency. We then develop an efficient and flexible estimation procedure that leverages advanced numerical and computation techniques. Thanks to a discretization based on finite elements in space and B-splines in time, the proposed method can effectively capture complex multi-modal and strongly anisotropic spatio-temporal point patterns; moreover, these point patterns may be observed over planar or curved domains with non -trivial geometries, due to geographic constraints, such as coastal regions with complicated shorelines, or curved regions with complex orography. In addition to providing estimates, the method's functionalities also include the introduction of appropriate uncertainty quantification tools. We thoroughly validate the proposed method, by means of simulation studies and applications to real-world data. The obtained results highlight significant advantages over state-of-the-art competing approaches

Group A Streptococcal Septic Hip Arthritis in a Child With Spastic Triplegic Cerebral Palsy

Reports of septic hip arthritis in children with cerebral palsy are exceedingly rare. This case report describes a 10-year-old boy with spastic triplegic cerebral palsy (Gross Motor Functional Classification System), who presented with fever and irritability. This case highlights the difficulties in diagnosing septic joint arthritis in patients with cerebral palsy who are nonverbal and have limited mobility. A high index of suspicion is necessary in this population when presented with fever and new limitations in mobility

Exercise-induced activation of STAT3 signaling is increased with age

Activation of the transcription factor signal transducers and activators of transcription (STAT) 3 is common to many inflammatory cytokines and growth factors, with recent evidence of involvement in skeletal muscle regeneration. The purpose of this study was to determine whether STAT3 signaling activation is regulated differentially, at rest and following intense resistance exercise, in aged human skeletal muscle. Skeletal muscle biopsies were harvested from healthy younger (n = 11, 20.4 &plusmn; 0.8 years) and older men (n = 10, 67.4 &plusmn; 1.3 years) under resting conditions and 2 h after the completion of resistance exercise. No differences were evident at rest, whereas the phosphorylation of STAT3 was significantly increased in old (23-fold) compared to young (5-fold) subjects after exercise. This correlated with significantly higher induction of the STAT3 target genes including; interleukin-6 (IL-6), JUNB, c-MYC, and suppressor of cytokine signaling (SOCS) 3 mRNA in older subjects following exercise. Despite increased SOCS3 mRNA, cellular protein abundance was suppressed. SOCS3 protein is an important negative regulator of STAT3 activation and cytokine signaling. Thus, in aged human muscle, elevated responsiveness of the STAT3 signaling pathway and suppressed SOCS3 protein are evident following resistance exercise. These data suggest that enhanced STAT3 signaling responsiveness to proinflammatory factors may impact on mechanisms of muscle repair and regeneration.<br /

Coccidioidal Pneumonia, Phoenix, Arizona, USA, 2000–2004

A prospective evaluation identified Coccidioides spp. as frequent causes of community-acquired pneumonia

The climate crisis, climate anxiety and children’s rights: a psychological perspective on human health and security

The climate crisis affects children’s well-being and threatens future generations’ enjoyment of the right to the highest standard of health and security. This paper discusses a submission by the PSI Special Interest Group in Human Rights and Psychology to the UN Committee on the Rights of the Child. As health profession stakeholders we highlight how environmental degradation and children’s awareness of climate change present an important linkage to children’s mental health. We provide a psychological health account of climate anxiety and its effects on children, and a psychological perspective on the UN Convention on the Rights of the Child regarding health and participation. We detail how interventions mindful of children’s educational and participatory capacity offer the potential to moderate effects of climate anxiety. We discuss limitations of the term ‘climate anxiety’ for describing the experience of children from the Global South, preferring a narrative of physical and mental health parity

Correction: Farnfield, M.M., et al. Whey Protein Ingestion Activates mTOR-dependent Signalling after Resistance Exercise in Young Men: A Double-Blinded Randomized Controlled Trial. Nutrients 2009, 1, 263-275.

We found an error in our paper recently published in Nutrients [1]

Pharmacologic Inhibition of COX-1 and COX-2 in Influenza A Viral Infection in Mice

BACKGROUND: We previously demonstrated that cyclooxygenase (COX)-1 deficiency results in greater morbidity and inflammation, whereas COX-2 deficiency leads to reduced morbidity, inflammation and mortality in influenza infected mice. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the effects of COX-1 and COX-2 inhibitors in influenza A viral infection. Mice were given a COX-1 inhibitor (SC-560), a COX-2 inhibitor (celecoxib) or no inhibitor beginning 2 weeks prior to influenza A viral infection (200 PFU) and throughout the course of the experiment. Body weight and temperature were measured daily as indicators of morbidity. Animals were sacrificed on days 1 and 4 post-infection and bronchoalveolar lavage (BAL) fluid was collected or daily mortality was recorded up to 2 weeks post-infection. Treatment with SC-560 significantly increased mortality and was associated with profound hypothermia and greater weight loss compared to celecoxib or control groups. On day 4 of infection, BAL fluid cells were modestly elevated in celecoxib treated mice compared to SC-560 or control groups. Viral titres were similar between treatment groups. Levels of TNF-alpha and G-CSF were significantly attenuated in the SC-560 and celecoxib groups versus control and IL-6 levels were significantly lower in BAL fluid of celecoxib treated mice versus control and versus the SC-560 group. The chemokine KC was significantly lower in SC-560 group versus control. CONCLUSIONS/SIGNIFICANCE: Treatment with a COX-1 inhibitor during influenza A viral infection is detrimental to the host whereas inhibition of COX-2 does not significantly modulate disease severity. COX-1 plays a critical role in controlling the thermoregulatory response to influenza A viral infection in mice