The ISIS Project: Indications for Future Near-Earth Plasma Studies through Future Galileo Satellites

The Earth’s plasmasphere variability is a consequence of the Sun’s forcing, determining our planet’s space weather. Plasmaspheric dynamics could be entirely caught only by studying together global and local proxies of the state of this extended system. The ISIS project (Inter-Satellite & In Situ plasmaspheric monitoring and modelling) aimed to design a system for the continuous monitoring of the Earth’s plasmasphere based on the future Galileo satellites. The efforts and expertise of ISC-CNR (Institute for Complex Systems of the National Research Council of Italy), INGV (Istituto Nazionale di Geofisica e Vulcanologia) and TAS-I (Thales Alenia Space - Italy) were put together in this work of assessment. ISIS Team proposed new experimental facilities of the Galileo satellites, designed to realize inter-satellite and in situ measurements to monitor global and local quantities; in particular, a scalable system of Langmuir probes was suggested, while the TEC along all possible inter-satellite ray paths throughout the plasmasphere could be monitored via phase- and group-delay analysis of inter-satellite radio signals

The ISIS Project: Indications for Future Near-Earth Plasma Studies through Future Galileo Satellites

The Earth’s plasmasphere variability is a consequence of the Sun’s forcing, determining our planet’s space weather. Plasmaspheric dynamics could be entirely caught only by studying together global and local proxies of the state of this extended system. The ISIS project (Inter-Satellite & In Situ plasmaspheric monitoring and modelling) aimed to design a system for the continuous monitoring of the Earth’s plasmasphere based on the future Galileo satellites. The efforts and expertise of ISC-CNR (Institute for Complex Systems of the National Research Council of Italy), INGV (Istituto Nazionale di Geofisica e Vulcanologia) and TAS-I (Thales Alenia Space - Italy) were put together in this work of assessment. ISIS Team proposed new experimental facilities of the Galileo satellites, designed to realize inter-satellite and in situ measurements to monitor global and local quantities; in particular, a scalable system of Langmuir probes was suggested, while the TEC along all possible inter-satellite ray paths throughout the plasmasphere could be monitored via phase- and group-delay analysis of inter-satellite radio signals.Published1A. Geomagnetismo e Paleomagnetismo2A. Fisica dell'alta atmosferaN/A or not JCRope

The ISIS Project: Indications for Future Near-Earth Plasma Studies through Future Galileo Satellites

The Earth’s plasmasphere variability is a consequence of the Sun’s forcing, determining our planet’s space weather. Plasmaspheric dynamics could be entirely caught only by studying together global and local proxies of the state of this extended system. The ISIS project (Inter-Satellite & In Situ plasmaspheric monitoring and modelling) aimed to design a system for the continuous monitoring of the Earth’s plasmasphere based on the future Galileo satellites. The efforts and expertise of ISC-CNR (Institute for Complex Systems of the National Research Council of Italy), INGV (Istituto Nazionale di Geofisica e Vulcanologia) and TAS-I (Thales Alenia Space - Italy) were put together in this work of assessment. ISIS Team proposed new experimental facilities of the Galileo satellites, designed to realize inter-satellite and in situ measurements to monitor global and local quantities; in particular, a scalable system of Langmuir probes was suggested, while the TEC along all possible inter-satellite ray paths throughout the plasmasphere could be monitored via phase- and group-delay analysis of inter-satellite radio signals

Reversals in nature and the nature of reversals

The asymmetric shape of reversals of the Earth's magnetic field indicates a possible connection with relaxation oscillations as they were early discussed by van der Pol. A simple mean-field dynamo model with a spherically symmetric $\alpha$ coefficient is analysed with view on this similarity, and a comparison of the time series and the phase space trajectories with those of paleomagnetic measurements is carried out. For highly supercritical dynamos a very good agreement with the data is achieved. Deviations of numerical reversal sequences from Poisson statistics are analysed and compared with paleomagnetic data. The role of the inner core is discussed in a spectral theoretical context and arguments and numerical evidence is compiled that the growth of the inner core might be important for the long term changes of the reversal rate and the occurrence of superchrons.Comment: 24 pages, 12 figure

Providing high-quality care remotely to patients with rare bone diseases during COVID-19 pandemic

During the COVID-19 outbreak, the European Reference Network on Rare Bone Diseases (ERN BOND) coordination team and Italian rare bone diseases healthcare professionals created the "COVID-19 Helpline for Rare Bone Diseases" in an attempt to provide high-quality information and expertise on rare bone diseases remotely to patients and healthcare professionals. The present position statement describes the key characteristics of the Helpline initiative, along with the main aspects and topics that recurrently emerged as central for rare bone diseases patients and professionals. The main topics highlighted are general recommendations, pulmonary complications, drug treatment, trauma, pregnancy, children and elderly people, and patient associations role. The successful experience of the "COVID-19 Helpline for Rare Bone Diseases" launched in Italy could serve as a primer of gold-standard remote care for rare bone diseases for the other European countries and globally. Furthermore, similar COVID-19 helplines could be considered and applied for other rare diseases in order to implement remote patients' care

Nano-Tubular Cellulose for Bioprocess Technology Development

Delignified cellulosic material has shown a significant promotional effect on the alcoholic fermentation as yeast immobilization support. However, its potential for further biotechnological development is unexploited. This study reports the characterization of this tubular/porous cellulosic material, which was done by SEM, porosimetry and X-ray powder diffractometry. The results showed that the structure of nano-tubular cellulose (NC) justifies its suitability for use in “cold pasteurization” processes and its promoting activity in bioprocessing (fermentation). The last was explained by a glucose pump theory. Also, it was demonstrated that crystallization of viscous invert sugar solutions during freeze drying could not be otherwise achieved unless NC was present. This effect as well as the feasibility of extremely low temperature fermentation are due to reduction of the activation energy, and have facilitated the development of technologies such as wine fermentations at home scale (in a domestic refrigerator). Moreover, NC may lead to new perspectives in research such as the development of new composites, templates for cylindrical nano-particles, etc

Spaces of Yoga – Towards a Non-Essentialist Understanding of Yoga

This chapter will examine some of the spaces that yoga occupies in the contemporary world, both physical and social. By looking at yoga through the focus of particular, contested spaces and locations, it will be argued that overarching essentialist definitions of yoga are impossible, although individuals and social groups can and do create essentialist definitions that are more or less useful for particular purposes. By exploring these narratives and boundaries in the context of specific locations, we can better understand what people are doing with the collection of beliefs and practices known as yoga

Risk classification at diagnosis predicts post-HCT outcomes in intermediate-, adverse-risk, and KMT2A-rearranged AML

Little is known about whether risk classification at diagnosis predicts post-hematopoietic cell transplantation (HCT) outcomes in patients with acute myeloid leukemia (AML). We evaluated 8709 patients with AML from the CIBMTR database, and after selection and manual curation of the cytogenetics data, 3779 patients in first complete remission were included in the final analysis: 2384 with intermediate-risk, 969 with adverse-risk, and 426 with KMT2A-rearranged disease. An adjusted multivariable analysis detected an increased risk of relapse for patients with KMT2A-rearranged or adverse-risk AML as compared to those with intermediate-risk disease (hazards ratio [HR], 1.27; P 5.01; HR, 1.71; P,.001, respectively). Leukemia-free survival was similar for patients with KMT2A rearrangement or adverse risk (HR, 1.26; P 5.002, and HR, 1.47; P,.001), as was overall survival (HR, 1.32; P,.001, and HR, 1.45; P,.001). No differences in outcome were detected when patients were stratified by KMT2A fusion partner. This study is the largest conducted to date on post-HCT outcomes in AML, with manually curated cytogenetics used for risk stratification. Our work demonstrates that risk classification at diagnosis remains predictive of post-HCT outcomes in AML. It also highlights the critical need to develop novel treatment strategies for patients with KMT2A-rearranged and adverse-risk disease