Effect of 16 hours Oxygen-Glucose Deprivation (OGD) on % survival of PC12 cells in the absence or presence of different combinations of caspase, calpain and aspartyl protease inhibition (10 µM/10 µM/5 µM).

<p>The values are presented as mean ± SEM, *p<0.05, **p<0.01. <b>Panel a</b>, naive PC12 cells, <b>panel b</b> PC12 cells NGF treated.</p

Effect of 16 hours Oxygen-Glucose Deprivation (OGD) on % survival of PC12 cells in the absence or presence of the permeable calpain inhibitor MDL28170 (10 µM, 50 µM and 100 µM).

<p>The values are presented as mean ± SEM, *p<0.05, **p<0.01, ***p<0,001. <b>Panel a</b>, naive PC12 cells, <b>panel b</b> PC12 cells NGF treated.</p

Effect of 16 hours Oxygen-Glucose Deprivation (OGD) on % survival of PC12 cells in the absence or presence of 10 µM and 50 µM of the specific caspase inhibitor z-VAD-fmk.

<p>The values are presented as mean ± SEM, *p<0.05, **p<0.01. <b>Panel a</b>, naive PC12 cells, <b>panel b</b> PC12 cells NGF treated.</p

Effect of 16 hours Oxygen-Glucose Deprivation (OGD) on % survival of PC12 cells in the absence or presence of different concentrations of the aspartyl protease inhibitor pepstatin A (1 µM and 5 µM).

<p>The values are presented as mean ± SEM, *p<0.05, **p<0.01. <b>Panel a</b>, naive PC12 cells, <b>panel b</b> PC12 cells NGF treated.</p