24,214 research outputs found
Selenocysteine, pyrrolysine and the unique energy metabolism of methanogenic archaea
Methanogenic archaea are a group of strictly anaerobic microorganisms characterized by their strict dependence on the process of methanogenesis for energy conservation. Among the archaea, they are also the only known group synthesizing proteins containing selenocysteine or pyrrolysine. All but one of the known archaeal pyrrolysine-containing and all but two of the confirmed archaeal selenocysteine-containing protein are involved in methanogenesis. Synthesis of these proteins proceeds through suppression of translational stop codons but otherwise the two systems are fundamentally different. This paper highlights these differences and summarizes the recent developments in selenocysteine- and pyrrolysine-related research on archaea and aims to put this knowledge into the context of their unique energy metabolism
Instantaneous quadrature low-coherence interferometry with 3x3 fiber-optic couplers
We describe fiber-based quadrature low-coherence interferometers that exploit the inherent phase shifts of 3 x 3 and higher-order fiber-optic couplers. We present a framework based on conservation of energy to account for the interferometric shifts in 3 x 3 interferometers, and we demonstrate that the resulting interferometers provide the entire complex interferometric signal instantaneously in homodyne and heterodyne systems. In heterodyne detection we demonstrate the capability for extraction of the magnitude and sign of Doppler shifts from the complex data. In homodyne detection we show the detection of subwavelength sample motion. N x N (N> 2) low-coherence interferometer topologies will be useful in Doppler optical coherence tomography (OCT), optical coherence microscopy, Fourier-domain OCT, optical frequency domain reflectometry, and phase-referenced interferometry
Fixed parameter tractability of crossing minimization of almost-trees
We investigate exact crossing minimization for graphs that differ from trees
by a small number of additional edges, for several variants of the crossing
minimization problem. In particular, we provide fixed parameter tractable
algorithms for the 1-page book crossing number, the 2-page book crossing
number, and the minimum number of crossed edges in 1-page and 2-page book
drawings.Comment: Graph Drawing 201
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