Bilateral Laryngoceles in Association with Squamos Cell Carcinoma: A Case Report and Literature Review

Coexistence of laryngoceles and laryngeal carcinoma is still being debated, and there are several suggested theories about the pathophysiological relationship between these two entities. We present the case of a 66-year-old male patient with bilateral laryngomucoceles and laryngeal squamos cell carcinoma. A systematic hystological examination of whole organ sections showed that the submucosal spreading of cancer around the saccular necks on both sides caused stenosis which probably created a one-way valve mechanism allowing air to enter the saccule but not to exit. Progression of the tumor completely obstructed the laryngeal opening, leading to glandular secretion stagnation and formation of laryngomucoceles

Bilateral Laryngoceles in Association with Squamos Cell Carcinoma: A Case Report and Literature Review

Coexistence of laryngoceles and laryngeal carcinoma is still being debated, and there are several suggested theories about the pathophysiological relationship between these two entities. We present the case of a 66-year-old male patient with bilateral laryngomucoceles and laryngeal squamos cell carcinoma. A systematic hystological examination of whole organ sections showed that the submucosal spreading of cancer around the saccular necks on both sides caused stenosis which probably created a one-way valve mechanism allowing air to enter the saccule but not to exit. Progression of the tumor completely obstructed the laryngeal opening, leading to glandular secretion stagnation and formation of laryngomucoceles

CERVICAL CANCER IN PREGNANT WOMEN Frequency and characteristics

Cilj. Odrediti učestalost raka vrata maternice u trudnica te opisati značajke svakog pojedinog slučaja. Metode. U razdoblju od 1.1.2000. do 31.12.2004. godine obradili smo 16071 trudnicu koja je boravila u Odjelu za ginekologiju i porodništvo KB Osijek. Rezultati. Histološki nalaz rak vrata maternice imale su 4 trudnice (2,5 na 10000), a prekancerozu (CIN III) 22 trudnice (14 na 10000 trudnica). Prosječna životna dob trudnica s rakom iznosila je 35,5 godina dok je prosječna životna dob žena s rakom vrata maternice općenito iznosila 53,4 godine. Jedna trudnica je imala rak FIGO stadij IA1, dvije su imale stadij IB2 i jedna stadij IIA. Veličina primarnoga tumora u trudnica s kliničkim rakom iznosila je 6; 6,5 i 7 cm i sve su imale pozitivne limfne čvorove male zdjelice (1, 5 i 9 čvorova). Zaključak. U jednom slučaju radilo se o ranoj stromalnoj invaziji (<1mm) koja se praktički može smatrati prekancerozom, s obzirom na način liječenja i prognozu. U svih ostalih se radilo o kliničkom raku s velikim primarnim tumorom i pozitivnom limfnim čvorovima male zdjelice. Pacijentica u koje je rak otkriven nakon poroda umrla je vrlo brzo nakon operacije, a ostale se redovito prate i nije ­zamijećen povrat bolesti.Objective. To identify the incidence of the cervix cancer in pregnant women and to describe the characteristics of each individual case that was diagnosed. Methods. In the period from January 1, 2000 to December 31, 2004 are ­analyzed 16,071 pregnant women who were hospitalized at the Department of Gynaecology and Obstetrics Clinical ­Hospital Osijek. Results. Histological finding of cervical cancer was established in 4 pregnant women (2.5 out of 10,000), and 22 pregnant women (14 out of 10,000) had precancerous lesions (CIN III). Average age of pregnant women with ­cancer was 35.5 years, and average age of women with invasive cervical cancer was in general 53.4 years. One pregnant woman had FIGO stage IA1, two women had stage IB2, and one had stage IIA. The size of the primary tumor in pregnant women with clinical cancer was 6, 6.5 and 7 cm, and all treated women had positive lymph nodes in the small pelvis (1, 5 and 9 nodes). Conclusion. In one case there was an early stromal invasion (<1 mm), which practically belongs to precancerous lesions, considering the treatment method and prediction. All other cases were clinical cancers with a large ­primary tumor and positive lymph nodes in the small pelvis. A patient in whom the cancer was diagnosed after parturition, died very soon after the surgery, and the others are under regular control and no illness recurrence has been noticed

Obostrane laringokele udružene s planocelularnim karcinomom: prikaz slučaja i osvrt na literaturu

Coexistence of laryngoceles and laryngeal carcinoma is still being debated, and there are several suggested theories about the pathophysiological relationship between these two entities. We present the case of a 66-year-old male patient with bilateral laryngomucoceles and laryngeal squamos cell carcinoma. A systematic hystological examination of whole organ sections showed that the submucosal spreading of cancer around the saccular necks on both sides caused stenosis which probably created a one-way valve mechanism allowing air to enter the saccule but not to exit. Progression of the tumor completely obstructed the laryngeal opening, leading to glandular secretion stagnation and formation of laryngomucocelesO istovremenom postojanju laringokela i karcinoma larinksa se još uvijek raspravlja. Postoji nekoliko predloženih teorija o patofiziološkim odnosima između ova dva entiteta. Predstavljamo slučaj 66-godišnjeg muškarca s bilateralni laringomukokelama i planocelularnim karcinomom larinksa. Patohistološka analiza pokazala je submukozno širenje karcinoma oko vrata mukokele na obje strane što je vjerojatno prouzročilo stenozu i stvorilo jednosmjerni ventil mehanizam koji omogućava ulaz zraka u laringokelu, ali ne i izlaz. Progresija tumora potpuno zatvara laringealni otvor, a što dovodi do stagnacije žljezdane sekrecije i stvaranja laringomukokele