IN-SYNC. VIII. Primordial Disk Frequencies in NGC 1333, IC 348, and the Orion A Molecular Cloud

In this paper, we address two issues related to primordial disk evolution in three clusters (NGC 1333, IC 348, and Orion A) observed by the INfrared Spectra of Young Nebulous Clusters (IN-SYNC) project. First, in each cluster, averaged over the spread of age, we investigate how disk lifetime is dependent on stellar mass. The general relation in IC 348 and Orion A is that primordial disks around intermediate mass stars (2--5$M_{\odot}$) evolve faster than those around loss mass stars (0.1--1$M_{\odot}$), which is consistent with previous results. However, considering only low mass stars, we do not find a significant dependence of disk frequency on stellar mass. These results can help to better constrain theories on gas giant planet formation timescales. Secondly, in the Orion A molecular cloud, in the mass range of 0.35--0.7$M_{\odot}$, we provide the most robust evidence to date for disk evolution within a single cluster exhibiting modest age spread. By using surface gravity as an age indicator and employing 4.5 $\mu m$ excess as a primordial disk diagnostic, we observe a trend of decreasing disk frequency for older stars. The detection of intra-cluster disk evolution in NGC 1333 and IC 348 is tentative, since the slight decrease of disk frequency for older stars is a less than 1-$\sigma$ effect.Comment: 25 pages, 26 figures; submitted for publication (ApJ

High signal-to-noise spectral characterization of the planetary-mass object HD 106906 b

We spectroscopically characterize the atmosphere of HD 106906b, a young low-mass companion near the deuterium burning limit. The wide separation from its host star of 7.1" makes it an ideal candidate for high S/N and high-resolution spectroscopy. We aim to derive new constraints on the spectral type, effective temperature, and luminosity of HD106906b and also to provide a high S/N template spectrum for future characterization of extrasolar planets. We obtained 1.1-2.5 $\mu$m integral field spectroscopy with the VLT/SINFONI instrument with a spectral resolution of R~2000-4000. New estimates of the parameters of HD 106906b are derived by analyzing spectral features, comparing the extracted spectra to spectral catalogs of other low-mass objects, and fitting with theoretical isochrones. We identify several spectral absorption lines that are consistent with a low mass for HD 106906b. We derive a new spectral type of L1.5$\pm$1.0, one subclass earlier than previous estimates. Through comparison with other young low-mass objects, this translates to a luminosity of log($L/L_\odot$)=$-3.65\pm0.08$ and an effective temperature of Teff=$1820\pm240$ K. Our new mass estimates range between $M=11.9^{+1.7}_{-0.8} M_{\rm Jup}$ (hot start) and $M=14.0^{+0.2}_{-0.5} M_{\rm Jup}$ (cold start). These limits take into account a possibly finite formation time, i.e., HD 106906b is allowed to be 0--3 Myr younger than its host star. We exclude accretion onto HD 106906b at rates $\dot{M}>4.8\times10^{-10} M_{\rm Jup}$yr$^{-1}$ based on the fact that we observe no hydrogen (Paschen-$\beta$, Brackett-$\gamma$) emission. This is indicative of little or no circumplanetary gas. With our new observations, HD 106906b is the planetary-mass object with one of the highest S/N spectra yet. We make the spectrum available for future comparison with data from existing and next-generation (e.g., ELT and JWST) spectrographs.Comment: 11 pages, 5 figures. Accepted for publication in Astronomy & Astrophysics. Fully reduced spectra will be made available for download on CD

Protoplanetary Disk Masses in the Young NGC 2024 Cluster

We present the results from a Submillimeter Array survey of the 887 micron continuum emission from the protoplanetary disks around 95 young stars in the young cluster NGC 2024. Emission was detected from 22 infrared sources, with flux densities from ~5 to 330 mJy; upper limits (at 3sigma) for the other 73 sources range from 3 to 24 mJy. For standard assumptions, the corresponding disk masses range from ~0.003 to 0.2Msolar, with upper limits at 0.002--0.01Msolar. The NGC 2024 sample has a slightly more populated tail at the high end of its disk mass distribution compared to other clusters, but without more information on the nature of the sample hosts it remains unclear if this difference is statistically significant or a superficial selection effect. Unlike in the Orion Trapezium, there is no evidence for a disk mass dependence on the (projected) separation from the massive star IRS2b in the NGC 2024 cluster. We suggest that this is due to either the cluster youth or a comparatively weaker photoionizing radiation field.Comment: ApJ, in pres

Ciprofloxacin and Clozapine: A Potentially Fatal but Underappreciated Interaction

Objective. Clozapine provides a 50%–60% response rate in refractory schizophrenia but has a narrow therapeutic index and is susceptible to pharmacokinetic interactions, particularly with strong inhibitors or inducers of cytochrome P450 (CYP) 1A2. Case Report. We report the case of a 28-year-old nonsmoking female with intellectual disability who was maintained for 3 years on clozapine 100 mg orally twice daily. The patient was treated for presumptive urinary tract infection with ciprofloxacin 500 mg orally twice daily and two days later collapsed and died despite resuscitation efforts. The postmortem femoral clozapine plasma level was dramatically elevated at 2900 ng/mL, and the cause of death was listed as acute clozapine toxicity. Conclusion. Given the potentially fatal pharmacokinetic interaction between clozapine and ciprofloxacin, clinicians are advised to monitor baseline clozapine levels prior to adding strong CYP450 1A2 inhibitors, reduce the clozapine dose by at least two-thirds if adding a 1A2 inhibitor such as ciprofloxacin, check subsequent steady state clozapine levels, and adjust the clozapine dose to maintain levels close to those obtained at baseline

IN-SYNC. V. Stellar kinematics and dynamics in the Orion A Molecular Cloud

The kinematics and dynamics of young stellar populations enable us to test theories of star formation. With this aim, we continue our analysis of the SDSS-III/APOGEE IN-SYNC survey, a high resolution near infrared spectroscopic survey of young clusters. We focus on the Orion A star-forming region, for which IN-SYNC obtained spectra of $\sim2700$ stars. In Paper IV we used these data to study the young stellar population. Here we study the kinematic properties through radial velocities ($v_r$). The young stellar population remains kinematically associated with the molecular gas, following a $\sim10\:{\rm{km\:s}}^{-1}$ gradient along filament. However, near the center of the region, the $v_r$ distribution is slightly blueshifted and asymmetric; we suggest that this population, which is older, is slightly in foreground. We find evidence for kinematic subclustering, detecting statistically significant groupings of co-located stars with coherent motions. These are mostly in the lower-density regions of the cloud, while the ONC radial velocities are smoothly distributed, consistent with it being an older, more dynamically evolved cluster. The velocity dispersion $\sigma_v$ varies along the filament. The ONC appears virialized, or just slightly supervirial, consistent with an old dynamical age. Here there is also some evidence for on-going expansion, from a $v_r$--extinction correlation. In the southern filament, $\sigma_v$ is $\sim2$--$3$ times larger than virial in the L1641N region, where we infer a superposition along the line of sight of stellar sub-populations, detached from the gas. On the contrary, $\sigma_v$ decreases towards L1641S, where the population is again in agreement with a virial state.Comment: 14 pages, 13 figures, ApJ accepte

Manipulation of the spontaneous emission dynamics of quantum dots in two-dimensional photonic crystals

We demonstrate the ability to control the spontaneous emission dynamics of self-assembled quantum dots via the local density of optical modes in 2D-photonic crystals. We show that an incomplete 2D photonic bandgap is sufficient to significantly lengthen the spontaneous emission lifetime ($>2\times$) over a wide bandwidth ($\Delta\lambda\geq40$ nm). For dots that are both \textit{spectrally} and \textit{spatially} coupled to strongly localized ($V_{mode}\sim1.5(\lambda/n)^{3}$), high $Q\sim2700$ optical modes, we have directly measured a strong Purcell enhanced shortening of the emission lifetime $\geq5.6\times$, limited only by our temporal resolution. Analysis of the spectral dependence of the recombination dynamics shows a maximum lifetime shortening of $19\pm4$. From the directly measured enhancement and suppression we show that the single mode coupling efficiency for quantum dots in such structures is at least $\beta=92$ and is estimated to be as large as $\sim97$.Comment: 11 pages, 3 figure