Tumori mozga i epilepsija

Brain tumors are a common cause of epilepsy. Tumor type and location are determining factors that significantly influence seizure frequency. The aim of this study was to analyze clinical data of patients diagnosed with brain tumors and epilepsy. Data for this study were obtained from patient medical records over a 6-year period (2000-2005). Patient history and findings obtained by diagnostic methods such as electroencephalography, computerized tomography and magnetic resonance were analyzed. Data were analyzed by appropriate statistical methods and the structure, prevalence, mean and standard deviation were calculated. The significance of results was tested by use of t-test and χ2-test. A total of 15 933 patient charts were analyzed. Out of 15 933 patients, 10.8% were diagnosed with epilepsy and 175 (1.09%) patients had brain tumor, 75 (42.86%) of which were significantly associated with epilepsy (P>0.05). Almost forty-three percent (42.86%) of tumors were epileptogenic, with no significant sex difference (confidence level of 95%). Fifty-seven (32.5%) brain tumor patients were aged 51-60. The mean age of all patients with brain tumors was 41.6 years. Focal sensorimotor seizures were dominant in 40 (53.3%) cases. Among epilepsy cases with known etiology, 75 (6.8%) patients had epileptogenic tumors. Types of seizures in patients with epilepsy were different from seizures provoked by brain tumors. The most common tumor site was temporal region (43.4%). There was no significant difference according to epileptogenesis. Focal sensorimotor seizures were common in patients with frontal and parietal region tumors.Tumori mozga su čest uzrok epilepsije. Vrst tumora i lokalizacija su odlučujući čimbenici koji značajno utječu na učestalost konvulzija. Cilj ove studije bio je analizirati kliničke podatke bolesnika s dijagnosticiranim tumorom mozga i epilepsijom. Podaci za studiju prikupljeni su iz medicinske dokumentacije bolesnika kroz 6-godišnje razdoblje, od 2000.do 2005. godine. Analizirani su anamnestički podaci i nalazi dobiveni dijagnostičkim metodama poput elektroencefalografije, kompjutorizirane tomografije i magnetske rezonancije. U analizi su se primijenile odgovarajuće statističke metode, te je izračunata struktura, učestalost te srednja vrijednost i standardna devijacija. Značajnost rezultata ispitana je pomoću t-testa i χ2-testa. Analiza je obuhvatila 15933 bolesničkih kartona. Od 15933 bolesnika epilepsija je bila dijagnosticirana u 10,8%; 175 (1,09%) bolesnika je imalo tumor mozga, od kojih je 75 (42,86%) bilo značajno udruženo s epilepsijom (P>0,05). Gotovo je 43% (točnije, 42,86%) tumora bilo epileptogeno, bez značajne razlike prema spolu, na razini pouzdanosti od 95%. Utvrđeno je 57 (32,5%) slučajeva tumora mozga među bolesnicima u dobi od 51 do 60 godina. Srednja dob svih bolesnika s tumorom mozga bila je 41,6 godina. Žarišni senzomotorni napadaji prevladavali su u 40 (53,3%) bolesnika. Među bolesnicima s epilepsijom poznate etiologije 75 (6,8%) ih je imalo epileptogene tumore. Vrste napadaja u bolesnika s epilepsijom razlikovale su se od napadaja izazvanih tumorom mozga. Najčešće mjesto tumora bilo je temporalno područje (43,4%) i nije bilo značajne razlike u odnosu na epileptogenezu. Žarišni senzomotorni napadaji bili su česti u bolesnika s tumorima frontalnog i parietalnog područja