Synthesis of α-amino phosphonates by diastereoselective addition of diethyl phosphite sodium salt to aldimines derived from Betti base

© 2016A diastereoselective (de 80–92%) synthesis of α-amino phosphonates was accomplished by reaction of diethyl phosphite sodium salt with 3-R-1-phenyl-2,3-dihydro-1H-naphth[1,2-e]-[1,3]oxazines being the products of aminoacetalization of aldehydes with 1-(α-aminobenzyl)-2-naphthol (Betti base)

Ni(II) complex of bisthiophosphorylated thiourea prepared from the Betti base

© 2017, Pleiades Publishing, Ltd. The interaction between bisthiophosphorylated thiourea with nickel(II) nitrate in the presence of potassium tert-butylate has afforded NiL 2 complex with square-planar configuration of the nickel(II) ion and the 1,3-N,S-coordination of the trans-positioned similar heteroatoms

Betti base in the synthesis of chiral bisphosphorylated thioureas

© 2017, Pleiades Publishing, Ltd. Phosphorylation of a naphthol hydroxy group of thiophosphorylated thiourea obtained by reaction of diethyl thiophosphoryl isothiocyanate with 1-(α-aminobenzyl)-2-naphthol (Betti base) afforded a number of chiral bisphosphorylated thioureas. Molecular structure of the obtained compounds was studied by single crystal X-ray diffraction. The capacity of the studied compounds for dimerization due to the intermolecular N–HS hydrogen bonding was revealed

A new synthetic route to chiral 3-aryl-5-ethyl-1,4,2-oxazaphosphorines

© 2018 Diastereoselective synthesis of racemic and enantiopure 3-aryl-5-ethyl-1,4,2-oxazaphosphorines, including those bearing phenolic hydroxyl groups in the exocyclic aromatic fragment, was implemented by the reaction of imines derived from (±)-and (R)-(−)-2-aminobutan-1-ol and (hydroxy)benzaldehydes with triethyl phosphite and trifluoroacetic acid, followed by the one-pot dealkylation of the intermediate esters

Phosphorylation of Betti Base with Bis(diethylamino)phosphoryl Chloride

© 2018, Pleiades Publishing, Ltd. The reaction of bis(diethylamino)phosphoryl chloride with N-Boc-protected 1-(α-aminobenzyl)-2- naphthol (Betti base) proceeded via O-phosphorylation of the phenolic OH group to form the target product as trifluoroacetate salt. The latter reacted with O,O-diethyl thiophosphorylisothiocyanate to give thiourea bearing a chiral Betti base fragment

Phosphorylation of betti base with diethyl chlorophosphate

© 2016, Pleiades Publishing, Ltd.Phosphoric acid derivatives containing chiral Betti base fragment were synthesized by reacting racemic and enantiopure N-Boc-protected 1-(α-aminobenzyl)-2-naphthols with diethyl chlorophosphate followed by deprotection

α-aminophosphonates and imines on the basis of citral, citronellal, and (-)-myrtenal

The Kabachnik-Fields reaction of citral with dialkyl phosphites in the presence alkyl amines; the imine formation reaction of E,Z-citral, R,S-citronellal, and (R)-(-)-myrtenal with primary amines; and Pudovik reactions of prenyl imines obtained with dialkyl phosphites or with O,O-dialkyl trimethylsilylphosphites were studied. On the basis of these studies, new unsaturated prenyl imines and α-aminophosphonates were prepared. Copyright © Taylor & Francis Group, LLC

Chiral thiophosphorylated thioureas: Synthesis, structure, and cyclization reaction

© 2014 Wiley Periodicals, Inc. A number of chiral racemic and enanthiopure thiophosphorylated thioureas were synthesized by the reaction of 2-aminobutan-1-ol and 1-(a-aminobenzyl)-2-naphthol with O,O-diethyl thiophosphoryl isothiocyanate. It was found that such thioureas undergo the cyclization reaction under basic conditions with hydrogen sulfide elimination and the formation of thiophosphorylated oxasines. XRay single crystal diffraction revealed that the structure of thiourea is close to the prereaction state of the cyclization reaction

Tracking of the formation of binuclear nickel complexes of [Ni<inf>2</inf>(µ-O<inf>2</inf>PR¹R²)<inf>2</inf>(bpy)<inf>4</inf>]Br<inf>2</inf> type by ESI and MALDI mass spectrometry

© 2017 Elsevier LtdThe formation of binuclear nickel complexes of type [Ni2(µ-O2PR1R2)2(bpy)4]Br2, where R1 = H, R2 = phenyl (Ph), 2,4,6-trimethylphenyl (Mes), 2,4,6-triisopropylphenyl (Tipp) or R1R2 = [sbnd]OCH2CH(Et)NHCH(Ph)[sbnd]; bpy = 2,2′-bipyridine, in solution and their fragmentation behavior have been investigated by ESI and MALDI mass spectrometry. It was found that binuclear cationic fragments [Ni2(µ-O2PR1R2)2(bpy)2Br]+ are characteristic ions displaying the formation of binuclear nickel(II) complexes in solution

First coordination polymer based on diterpenoids. Synthesis, structure, and magnetic properties

© 2017, Springer Science+Business Media, LLC. One-dimensional coordination polymer was obtained by cation exchange reaction of triethylammonium salt of methyl ent-16α-H-phosphonyloxybeyeran-19-oate with CuCl 2 . Its structure was determined by single crystal X-ray diffraction analysis. The formation of hydrophilic channels consisting of phosphorus containing fragments, copper atoms, and water, which are framed by hydrophobic surroundings from tetracyclic bulky beyeran substituents, is observed in the crystal. The study of the temperature dependence of the static magnetic susceptibility of the polymer indicates a weak antiferromagnetic interaction between the copper spins