93 research outputs found

    Corrigendum to “The status of depression and anxiety in infertile Turkish couples” [Iran J Reprod Med 2011; 9: 99-104]

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    The publisher has been informed of an error that occurred on page 99 in which the second authors name must be changed to Ozlem Kayacik Gunday. On behalf of the author, the publisher wishes to apologize for this error. The online version of article has been updated on 31 August 2023 and can be found at https://doi.org/10.18502/ijrm.v9i2.104

    Relationship between MPV and paraoxonase-1 activity, brachial artery diameter and IMT in patients with diabetes mellitus

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    Aims: Higher mean platelet volume (MPV) in diabetic patients has been considered as an emerging risk factor for diabetes related micro- and macrovascular complications. Human paraoxonase 1/arylesterase (PON1), which has antioxidant and antiatherogenic properties, is documented in high oxidative stress conditions like uncontrolled diabetes. The present study aimed to evaluate the relationship between mean platelet volume (MPV) and paraoxonase-1 (PON-1) activity, brachial artery diameter (BAd) and intima media thickness (BA-IMT), in diabetic patients with regard to obesity and diabetic complications.Methods: Two-hundred and one diabetic patients (mean age: 52.4 ± 13.4 years, 73.6% females) were grouped according to obesity and diabetic complications (microvascular and macrovascular). Data on demographics, anthropometrics, diabetic complications, MPV levels, BAd and BA-IMT, and serum paraoxonase and arylesterase activities were recorded. The correlation of MPV values to paraoxonase and arylesterase activities, BAd and BA-IMT was evaluated.Results: Paraoxonase and arylesterase values were 119.8 ± 37.5 U/L and 149.0 ± 39.9 U/L, respectively, with no significant difference in respect of obesity and macrovascular complications. Significantly lower values for paraoxonase (107.5 ± 30.7 vs. 123.9 ± 38.8 U/L, p = 0.007) and arylesterase (132.1 ± 30.2 vs. 154.7 ± 41.2, U/L, p = 0.001) were noted in patients with microvascular complications. MPV values were 9.10 ± 0.87 fL, with no significant difference across the groups and no significant correlation with other parameters.Conclusion: In conclusion, PON-1 activity is more significantly decreased in diabetic patients with microvascular than macrovascular complications with no effects on MPV values. On the other hand, no relationship was found between thrombogenic activity and PON-1 activity, BAd and BA-IMT regardless of obesity and diabetic complications.Keywords: cardiovascular, diabetes, insulin resistance, obesity, vasculatur

    Rheological and sensorial behavior of tomato product enriched with pea protein and olive powder

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    In this study, a new functional product using Mediterranean ingredients (tomato, tomato peel powder and olive powder) was formulated where two different concentrations of protein (1 and 2%) and peel (2 and 4%) were tested. Olive powder was kept at a constant concentration of 2%. Physico-chemical, Rheological, and Sensorial analysis were carried out on the formulated samples. Soluble protein content was found as the highest in the sample containing 4% peel and 2% protein and it was affected by the pH and tomato peel concentration. Rheological results reveal shear-thinning behavior, as defined by the Herschel-Bulkley model, with protein and peel concentrations having a major influence on yield stress and viscosity. A positive trend was noticed between apparent viscosity and peel concentration, meantime protein concentration affected apparent viscosity adversely. Contrary relation between consistency index (k) values and apparent viscosity illustrate the complex interaction between protein and peel, particularly at higher concentrations. Furthermore, Principal Component Analysis (PCA) was used to investigate the complicated sensory landscape of tomato products with different quantities of pea protein and tomato peel. While higher tomato peel and protein levels have no direct impact on rheological qualities, they do add to astringency and sourness, which influences overall acceptability. Remarkably, the sample with the greatest quantities of peel and protein exhibits a delicate balance, with a loss in perceived tomato taste intensity and overall acceptability offsetting an increase in astringency. In terms of overall acceptability, the most preferred beverage was selected as the sample formulated with 2% peel and 1% protein

    Effects of Cigarette Smoking across Three Generations and of Perceptions of the Smoking-Cancer Relationship on the Cigarette Smoking Status of Turkish University Students

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    Background: This descriptive and cross-sectional study aimed to investigate effects of cigarette smoking across three generations and perceptions of the smoking-cancer relationship on the cigarette smoking status of Turkish university students. Materials and Methods: The study sample comprised of 434 university students studying in different departments of a university. Data were collected using a socio-demographic data collection form and the Decisional Balance Scaleqand evaluated using the Mann-Whitney U test, CHAID and multiple regression analyses. Results: The average age of the students participating in the study is 19.6+.5.0, some 11.3% of the students reporting that they smoked cigarettes. No statistically significant relationship was ascertained between the cigarette smoking statuses of the students based on the cigarette smoking status of their grandparents (p=0.144). but there was alink to that of their parents (p=0.002). The difference between the cigarette smoking ratios of the students based on their perceptions of smoking-cancer relationship was statistically significant (p<0.001). Believing that there is a relationship between smoking and cancer decreased likelihood of cigarette smoking 3.7 fold. Cigarette smoking by grandparents, and believing that there is a relationship between smoking and cancer, and cigarette smoking by parents explained 8.3% of the cigarette smoking status of the students. Conclusions: While cigarette smoking by grandparents only indirectly influences cigarette smoking by the students, believing that there is a relationship between smoking and cancer, and cigarette smoking by parents are influential variables in determining cigarette smoking by Turkish students

    Comparison of sysmex UF-5000 flow cytometer and fuchs-rosenthal chamber urine sediment analysis

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    Urine analysis is a routine test performed in clinical practice. Urine sediment analysis is a part of urinalysis that provides precious information to laboratory professionals. Manual review is an application which is time-consuming, as it is the gold standard for analysis. In this study, it was aimed to compare urine sediment analysis performance of the Sysmex UF-5000 flow cytometer with the manual Fuchs-Rosenthal counting chamber. From outpatient clinics, a total of 127 fresh urine samples were analyzed. Sysmex UF-5000 fluorescence flow cytometer was used for urine analysis and Fuchs-Rosenthal counting chamber was used for urine sediment analysis. Two methods were compared using Pearson correlation coefficient (r), Passing-Bablok regression analysis and Bland-Altman plot. CLSI Statis-Pro software version 3.0, Microsoft Excel 2010 and Analyse-it software version 3.80 (Analyse-it Software, Ltd., Leeds, UK) were used. A good correlation was observed between automated and manual white blood cell (WBC) counts in 71 urine samples (r = 0.988; y = 1.162x + 0.489; n = 127). The UF-5000 showed a significant proportional overestimation with the Passing-Bablok regression (95% CI slope: 1.110 to 1.226). Correlation between the counting chamber and UF-5000 was observed in 77 samples for red blood cell (RBC) counts (r=0.996; y=1.1x+0.75). This study showed that flow cytometry urinalysis is a promising area compared to the manual reference method. Urine analyzer automation is commonly used in clinical laboratories all over the world and is effective in reducing report time and workload. [Med-Science 2022; 11(1.000): 367-71

    Species diversity and dominancy indexes in Izmir Bay (Aegean Sea) purse seine fishery

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    GULEC, Ozlem/0000-0003-2217-2316WOS:000605750900005Purse seine fishery is known with its importance in Aegean Sea to catch pelagic species. in this study, to determine the diversity index values of species caught by purse seine, all samplings were carried out between September 2, 2017, and April 6, 2018 in Izmir Bay. As a result, a total of 17 fish species (Osteichthyes) belonging to 11 families and also 2 species from invertebrates (Cephalopoda and Arthropoda) were determined. Bony fishes and invertebrates consist of 99.9% and 0.1% of the total biomass, respectively. Sardina pilchardus was the most dominated species that occupied as 80.2% of the overall bony fishes followed by Engraulis encrasicolus (14.6%) and Sardinella aurita (1.5%). Diversity index values of species were found-1.026 by Shannon-Weaver and 0.63 by Simpsons, respectively. The highest dominancy was found for S. pilchardus with 71.1%. Overall final results indicate that the diversity of species in Izmir Bay purse seine fishery is very low and also S. pilchardus is the most over-dominant species.Ege University Scientific Research Project Coordination UnitEge University [2017/SUF/002]We would like to thank Ege University Scientific Research Project Coordination Unit (Project No.2017/SUF/002), project researcher and Afala purse seiner staff

    Should fluid management in thoracic surgery be goal directed?

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    Purpose of review To find a reliable answer to the question in the title: Should fluid management in thoracic surgery be goal directed? Recent findings 'Moderate' fluid regimen is the current recommendation of fluid management in thoracic anesthesia, however, especially in more risky patients; 'Goal-Directed Therapy' (GDT) can be a more reliable approach than just 'moderate'. There are numerous studies examining its effects in general anesthesia; albeit mostly retrospective and very heterogenic. There are few studies of GDT in thoracic anesthesia with similar drawbacks. Although the evidence level is low, GDT is generally associated with fewer postoperative complications. It can be helpful in decision-making for volume-optimization, timing of fluid administration, and indication of vasoactive agents

    Recent Developments in Enzyme, DNA and Immuno-Based Biosensors

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    WOS: 000436774300258PubMed ID: 29899282Novel sensitive, rapid and economical biosensors are being developed in a wide range of medical environmental and food applications. In this paper, we review some of the main advances in the field over the past few years by discussing recent studies from literature. A biosensor, which is defined as an analytical device consisting of a biomolecule, a transducer and an output system, can be categorized according to the type of the incorporated biomolecule. The biomolecules can be enzymes, antibodies, ssDNA, organelles, cells etc. The main biosensor categories classified according to the biomolecules are enzymatic biosensors, immunosensors and DNA-based biosensors. These sensors can measure analytes produced or reduced during reactions at lower costs compared to the conventional detection techniques. Numerous types of biosensor studies conducted over the last decade have been explored here to reveal their key applications in medical, environmental and food industries which provide comprehensive perspective to the readers. Overviews of the working principles and applications of the reviewed sensors are also summarized

    Idiopathic Childhood Occipital Lobe Epilepsies in Turkish Children

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    Purpose: Two forms of idiopathic occipital lobe epilepsy can be distinguished: an early onset or Panayiotopoulos type (PS), and a late onset or Gastaut type (GS). The aim of this study was to identify clinical manifestations and outcome in Turkish children with idiopathic occipital lobe epilepsy. Materials and Methods: Thirty nine children (27 boys, 12 girls) were divided into the PS and GS type, according to the classification for epileptic seizures of the International League Against Epilepsy. Results: Among the 39 patients, 27 (69.3%) were boys and 12 (30.7%) were girls and the mean age at the seizure onset was 77.38 +/- 27.33 months (36-145 months). The PS type patients consisted of 27 children (19 boys, 8 girls). The average age of seizure onset in PS type patients was 60.76 +/- 14.21 months (range, 36-94 months). The GS type patients consisted of 12 children (8 boys, 4 girls), and seizure onset was 107.7 +/- 18.8 months (range, 72-145 months). Ictal vomiting was more common in the PS type patients, and visual symptoms were more common in the GS type patients. We detected that after treatment, 27 patients (100%) in PS type and 10 patients (83.3%) in GS type became seizures-free. Two patients continued having seizures in GS type. Conclusions: The average age of seizure onset was much younger in the PS than in the GS. Also, in idiopathic occipital lobe epilepsy, the PS type has better seizure-free and prognosis than the GS. [Cukurova Med J 2015; 40(3.000): 504-509

    Trisomy 9 Mosaicism Presenting with Epilepsy, and Facial Dysmorphism: A Case Report

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    Trisomy 9 syndrome is a rare genetic disorder. Trisomy 9 has two forms; 1) mosaic, 2) non-mosaic. The patients usually present similar clinical features, independent of the presence of mosaicism, characterized by growth retardation, mental deficiency and brain, facial, cardiac, renal and skeletal abnormalities. Developmental delay and mental retardation are the most common neurological symptom in trisomy 9 mosaicism in our knowledge. Epilepsy associated with this syndrome has not found in literature. We describe a 10-year-old boy with trisomy 9 mosaicism who presented seizures, and dysmorfic features. [Cukurova Med J 2014; 39(2.000): 343-346
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