1,747 research outputs found
America’s Coming of Age: Daniel Walker Howe’s What Hath God Wrought
According to Daniel Walker Howe, the three decades between the end of the War of 1812 and the end of the Mexican War (1848) witnessed “the transformation of America.”1 Of what did this transformation consist? What drove it? What were its larger implications? These questions lie at the very center of historical writing about the early and middle decades of nineteenth- century America. Howe’s monumental effort goes far in answering them. In the process, he upends several well-known interpretations of the so-called Jacksonian period
Diversity and dispersal of a ubiquitous protein family: acyl-CoA dehydrogenases
Acyl-CoA dehydrogenases (ACADs), which are key enzymes in fatty acid and amino acid catabolism, form a large, pan-taxonomic protein family with at least 13 distinct subfamilies. Yet most reported ACAD members have no subfamily assigned, and little is known about the taxonomic distribution and evolution of the subfamilies. In completely sequenced genomes from approximately 210 species (eukaryotes, bacteria and archaea), we detect ACAD subfamilies by rigorous ortholog identification combining sequence similarity search with phylogeny. We then construct taxonomic subfamily-distribution profiles and build phylogenetic trees with orthologous proteins. Subfamily profiles provide unparalleled insight into the organisms’ energy sources based on genome sequence alone and further predict enzyme substrate specificity, thus generating explicit working hypotheses for targeted biochemical experimentation. Eukaryotic ACAD subfamilies are traditionally considered as mitochondrial proteins, but we found evidence that in fungi one subfamily is located in peroxisomes and participates in a distinct β-oxidation pathway. Finally, we discern horizontal transfer, duplication, loss and secondary acquisition of ACAD genes during evolution of this family. Through these unorthodox expansion strategies, the ACAD family is proficient in utilizing a large range of fatty acids and amino acids—strategies that could have shaped the evolutionary history of many other ancient protein families
Limits on WWZ and WW\gamma couplings from p\bar{p}\to e\nu jj X events at \sqrt{s} = 1.8 TeV
We present limits on anomalous WWZ and WW-gamma couplings from a search for
WW and WZ production in p-bar p collisions at sqrt(s)=1.8 TeV. We use p-bar p
-> e-nu jjX events recorded with the D0 detector at the Fermilab Tevatron
Collider during the 1992-1995 run. The data sample corresponds to an integrated
luminosity of 96.0+-5.1 pb^(-1). Assuming identical WWZ and WW-gamma coupling
parameters, the 95% CL limits on the CP-conserving couplings are
-0.33<lambda<0.36 (Delta-kappa=0) and -0.43<Delta-kappa<0.59 (lambda=0), for a
form factor scale Lambda = 2.0 TeV. Limits based on other assumptions are also
presented.Comment: 11 pages, 2 figures, 2 table
Zgamma Production in pbarp Collisions at sqrt(s)=1.8 TeV and Limits on Anomalous ZZgamma and Zgammagamma Couplings
We present a study of Z +gamma + X production in p-bar p collisions at
sqrt{S}=1.8 TeV from 97 (87) pb^{-1} of data collected in the eegamma
(mumugamma) decay channel with the D0 detector at Fermilab. The event yield and
kinematic characteristics are consistent with the Standard Model predictions.
We obtain limits on anomalous ZZgamma and Zgammagamma couplings for form factor
scales Lambda = 500 GeV and Lambda = 750 GeV. Combining this analysis with our
previous results yields 95% CL limits |h{Z}_{30}| < 0.36, |h{Z}_{40}| < 0.05,
|h{gamma}_{30}| < 0.37, and |h{gamma}_{40}| < 0.05 for a form factor scale
Lambda=750 GeV.Comment: 17 Pages including 2 Figures. Submitted to PR
Measurement of the Boson Mass
A measurement of the mass of the boson is presented based on a sample of
5982 decays observed in collisions at
= 1.8~TeV with the D\O\ detector during the 1992--1993 run. From a
fit to the transverse mass spectrum, combined with measurements of the
boson mass, the boson mass is measured to be .Comment: 12 pages, LaTex, style Revtex, including 3 postscript figures
(submitted to PRL
Search for First Generation Scalar Leptoquark Pairs in ppbar Collisions at sqrt(s)=1.8 TeV
We have searched for first generation scalar leptoquark (LQ) pairs in the
enu+jets channel using ppbar collider data (integrated luminosity= 115 pb^-1)
collected by the DZero experiment at the Fermilab Tevatron during 1992-96. The
analysis yields no candidate events. We combine the results with those from the
ee+jets and nunu+jets channels to obtain 95% confidence level (CL) upper limits
on the LQ pair production cross section as a function of mass and of beta, the
branching fraction to a charged lepton. Comparing with the next-to-leading
order theory, we set 95% CL lower limits on the LQ mass of 225, 204, and 79
GeV/c^2 for beta=1, 1/2, and 0, respectively.Comment: 14 pages, 4 figures, submitted to Physical Review Letters Replaced to
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Search for Top Squark Pair Production in the Dielectron Channel
This report describes the first search for top squark pair production in the
channel stop_1 stopbar_1 -> b bbar chargino_1 chargino_1 -> ee+jets+MEt using
74.9 +- 8.9 pb^-1 of data collected using the D0 detector. A 95% confidence
level upper limit on sigma*B is presented. The limit is above the theoretical
expectation for sigma*B for this process, but does show the sensitivity of the
current D0 data set to a particular topology for new physics.Comment: Five pages, including three figures, submitted to PRD Brief Report
Direct Measurement of the Top Quark Mass at D0
We determine the top quark mass m_t using t-tbar pairs produced in the D0
detector by \sqrt{s} = 1.8 TeV p-pbar collisions in a 125 pb^-1 exposure at the
Fermilab Tevatron. We make a two constraint fit to m_t in t-tbar -> b W^+bbar
W^- final states with one W boson decaying to q-qbar and the other to e-nu or
mu-nu. Likelihood fits to the data yield m_t(l+jets) = 173.3 +- 5.6 (stat) +-
5.5 (syst) GeV/c^2. When this result is combined with an analysis of events in
which both W bosons decay into leptons, we obtain m_t = 172.1 +- 5.2 (stat) +-
4.9 (syst) GeV/c^2. An alternate analysis, using three constraint fits to fixed
top quark masses, gives m_t(l+jets) = 176.0 +- 7.9 (stat) +- 4.8 (syst)
GeV/C^2, consistent with the above result. Studies of kinematic distributions
of the top quark candidates are also presented.Comment: 43 pages, 53 figures, 33 tables. RevTeX. Submitted to Phys. Rev.
Search for a Fourth Generation Charge -1/3 Quark via Flavor Changing Neutral Current Decay
We report on a search for pair production of a fourth generation charge -1/3
quark (b') in pbar p collisions at sqrt(s) = 1.8 TeV at the Fermilab Tevatron
using an integrated luminosity of 93 pb^-1. Both quarks are assumed to decay
via flavor changing neutral currents (FCNC). The search uses the signatures
gamma + 3 jets + mu-tag and 2 gamma + 2 jets. We see no significant excess of
events over the expected background. We place an upper limit on the production
cross section times branching fraction that is well below theoretical
expectations for a b' quark decaying exclusively via FCNC for b' quark masses
up to m(Z) + m(b).Comment: Eleven pages, two postscript figures, submitted to Physical Review
Letter
Measurement of Dijet Angular Distributions and Search for Quark Compositeness
We have measured the dijet angular distribution in =1.8 TeV
collisions using the D0 detector. Order QCD
predictions are in good agreement with the data. At 95% confidence the data
exclude models of quark compositeness in which the contact interaction scale is
below 2 TeV.Comment: 11 pages, Latex, 3 postscript figure
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