Social pedagogy and inter-professional practice : evaluation of Orkney Islands training programme

From February to September 2011, a social pedagogy training programme was provided for 18 staff from across Orkney Islands Council education and social care services. The initiative was jointly funded by Orkney Islands Council and the Scottish Institute for Residential Child Care (SIRCC), now the Centre for excellence for looked after children in Scotland (CELCIS). The Orkney initiative was the first instance in Scotland of an inter-agency group of participants undertaking the course together. The purpose of the evaluation was to provide systematic evidence of the impact that the social pedagogy training had on participants’ day-to-day practice and inter-agency or inter-professional working. The evaluation questions were: 1.What was the impact of the training on participants’ day-to-day practice? 2.What impact did the provision of social pedagogy training to multi-agency participants have on their inter-professional and inter-agency collaboration? 3.What helped and hindered the process of building inter-agency collaboration and what key challenges can be identified

How rural coworking hubs can facilitate well-being through the satisfaction of key psychological needs

Once considered an urban phenomenon, rural enterprise hubs (REH) and rural coworking spaces (RCWS) are now increasing in popularity to support entrepreneurial rural communities. Whilst previous research has examined economic and community benefits, a focus on well-being benefits has been overlooked. Framed by self-determination theory, this empirical research investigates whether rural coworking is reported to enhance user’s well-being by fulfilling key psychological needs for autonomy, competence and relatedness. By applying a well-being focus, we found that potential key drivers of rural coworking uptake and durability could be elucidated, in terms of these three needs. In addition, we identified another category of well-being that was fulfilled through engagement with RCWS and REH – namely – ‘communion with nature’. We suggest that considerations of well-being are important to understand how rural coworking can attract and sustain local workers and suggest a future research agenda to further conceptualise well-being effects

NS-NS fluxes in Hitchin's generalized geometry

The standard notion of NS-NS 3-form flux is lifted to Hitchin's generalized geometry. This generalized flux is given in terms of an integral of a modified Nijenhuis operator over a generalized 3-cycle. Explicitly evaluating the generalized flux in a number of familiar examples, we show that it can compute three-form flux, geometric flux and non-geometric Q-flux. Finally, a generalized connection that acts on generalized vectors is described and we show how the flux arises from it.Comment: 21 pages, 1 figure; v3: minor change

ArsRS-Dependent Regulation of homB Contributes to Helicobacter pylori Biofilm Formation

One elusive area in the Helicobacter pylori field is an understanding of why some infections result in gastric cancer, yet others persist asymptomatically for the life-span of the individual. Even before the genomic era, the high level of intraspecies diversity of H. pylori was well recognized and became an intriguing area of investigation with respect to disease progression. Of interest in this regard is the unique repertoire of over 60 outer membrane proteins (OMPs), several of which have been associated with disease outcome. Of these OMPs, the association between HomB and disease outcome varies based on the population being studied. While the molecular roles for some of the disease-associated OMPs have been evaluated, little is known about the role that HomB plays in the H. pylori lifecycle. Thus, herein we investigated homB expression, regulation, and contribution to biofilm formation. We found that in H. pylori strain G27, homB was expressed at a relatively low level until stationary phase. Furthermore, homB expression was suppressed at low pH in an ArsRS-dependent manner; mutation of arsRS resulted in increased homB transcript at all tested time-points. ArsRS regulation of homB appeared to be direct as purified ArsR was able to specifically bind to the homB promoter. This regulation, combined with our previous finding that ArsRS mutations lead to enhanced biofilm formation, led us to test the hypothesis that homB contributes to biofilm formation by H. pylori. Indeed, subsequent biofilm analysis using a crystal-violet quantification assay and scanning electron microscopy (SEM) revealed that loss of homB from hyper-biofilm forming strains resulted in reversion to a biofilm phenotype that mimicked wild-type. Furthermore, expression of homB in trans from a promoter that negated ArsRS regulation led to enhanced biofilm formation even in strains in which the chromosomal copy of homB had been deleted. Thus, homB is necessary for hyper-biofilm formation of ArsRS mutant strains and aberrant regulation of this gene is sufficient to induce a hyper-biofilm phenotype. In summary, these data suggest that the ArsRS-dependent regulation of OMPs such as HomB may be one mechanism by which ArsRS dictates biofilm development in a pH responsive manner