30 research outputs found
Revisiting CP-violation in Minimal Flavour Violation
After a brief review of the minimal flavour violation hypothesis and its
implementation in the MSSM, the most general parametrisation of the soft
supersymmetry-breaking terms by means of the charged lepton and neutrino
spurions is constructed. Thereby a type I seesaw mechanism is assumed to
generate neutrino masses. This expansion introduces several new CP-violating
phases, whose effects on the leptonic electric dipole moments are investigated.Comment: Talk given at the International Workshop on Effective Field Theories:
from the pion to the upsilon, February 2-6 2009, Valencia, Spai
Towards a determination of the tau lepton dipole moments
The tau anomalous magnetic moment (a_tau) and electric dipole moment (d_tau)
have not yet been observed. The present bounds on their values are of order
10^-2 and 10^-17 e*cm, respectively. We propose to measure a_tau with a
precision of O(10^-3) or better and improve the existing limits on d_tau using
precise tau- -> l- nu_tau \bar{nu}_l gamma (l=e or mu) data from
high-luminosity B factories. A detailed feasibility study of this method is
underway.Comment: 4 pages, presented at the 12th International Workshop on Tau Lepton
Physics, Nagoya, Japan, 17-21 September 201
B -> X_d gamma and constraints on new physics
We combine recent progress in measuring the branching ratio of the decay
B->X_d gamma$ with the discovery that hadronic uncertainties in the CP-averaged
branching ratio drop out to a large extent. Implications of these improvements
on the size of possible new physics effects are investigated. We find the
updated SM prediction for the CP-averaged branching ratio to be Br[B->X_d
gamma]^SM_E_gamma>1.6 GeV = 1.54^+0.26-0.31*10^-5, which should be compared
with the experimental value of Br[B->X_d gamma]^exp_E_gamma>1.6GeV =
(1.41+-0.57) 10^-5. After performing a model independent analysis, we consider
different new physics models: the MSSM with generic sources of flavor
violation, the two Higgs doublet model of type III and a model with
right-handed charged currents. It is found that the constraints on the SUSY
parameters delta^d_13 have improved and that the absolute value of the
right-handed quark mixing matrix element |V^R_td| must be smaller than
1.5*10^-4.Comment: 5 pages, 3 figures, experimental value for b->d+gamma corrected,
version accepted for publication in PR
Phantom study for 90Y post-treatment dosimetry with a long axial field-of-view PET/CT
Purpose: The physical properties of yttrium-90 (90Y) allow for imaging with
positron emission tomography/computed tomography (PET/CT). The increased
sensitivity of long axial field-of-view (LAFOV) PET/CT scanners possibly allows
to overcome the small branching ratio for positron production from 90Y decays
and to improve for the post-treatment dosimetry of 90Y of selective internal
radiation therapy.
Methods: For the challenging case of an image quality body phantom, we
compare a full Monte Carlo (MC) dose calculation with the results from the two
commercial software packages Simplicit90Y and Hermes. The voxel dosimetry
module of Hermes relies on the 90Y images taken with a LAFOV PET/CT, while the
MC and Simplicit90Y dose calculations are image independent.
Results: The resulting doses from the MC calculation and Simplicit90Y agree
well within the error margins. The image-based dose calculation with Hermes,
however, consistently underestimates the dose. This is due to the mismatch of
the activity distribution in the PET images and the size of the volume of
interest. Furthermore, there are likely limitations of Hermes' dose calculation
algorithm for 90Y. We found that only for the smallest phantom sphere there is
a statistically significant dependence of the Hermes dose on the image
reconstruction parameters and scan time.
Conclusion: Our study shows that Simplicit90Y's local deposition model can
provide a reliable dose estimate. On the other hand, the image based dose
calculation requires further benchmarks and verification in order to take full
advantage of LAFOV PET/CT systems
Semi-classical Monte Carlo algorithm for the simulation of X-ray grating interferometry.
Traditional simulation techniques such as wave optics methods and Monte Carlo (MC) particle transport cannot model both interference and inelastic scattering phenomena within one framework. Based on the rules of quantum mechanics to calculate probabilities, we propose a new semi-classical MC algorithm for efficient and simultaneous modeling of scattering and interference processes. The similarities to MC particle transport allow the implementation as a flexible c++ object oriented extension of EGSnrc-a well-established MC toolkit. In addition to previously proposed Huygens principle based transport through optics components, new variance reduction techniques for the transport through gratings are presented as transport options to achieve the required improvement in speed and memory costs necessary for an efficient exploration (system design-dose estimations) of the medical implementation of X-ray grating interferometry (GI), an emerging imaging technique currently subject of tremendous efforts towards clinical translation. The feasibility of simulation of interference effects is confirmed in four academic cases and an experimental table-top GI setup. Comparison with conventional MC transport show that deposited energy features of EGSnrc are conserved
Phantom-based evaluation of yttrium-90 datasets using biograph vision quadra.
PURPOSE
The image quality characteristics of two NEMA phantoms with yttrium-90 (90Y) were evaluated on a long axial field-of-view (AFOV) PET/CT. The purpose was to identify the optimized reconstruction setup for the imaging of patients with hepatocellular carcinoma after 90Y radioembolization.
METHODS
Two NEMA phantoms were used, where one had a 1:10 sphere to background activity concentration ratio and the second had cold background. Reconstruction parameters used are as follows: iterations 2 to 8, Gaussian filter 2- to 6-mm full-width-at-half-maximum, reconstruction matrices 440 × 440 and 220 × 220, high sensitivity (HS), and ultra-high sensitivity (UHS) modes. 50-, 40-, 30-, 20-, 10-, and 5-min acquisitions were reconstructed. The measurements included recovery coefficients (RC), signal-to-noise ratio (SNR), background variability, and lung error which measures the residual error in the corrections. Patient data were reconstructed with 20-, 10-, 5-, and 1-min time frames and evaluated in terms of SNR.
RESULTS
The RC for the hot phantom was 0.36, 0.45, 0.53, 0.63, 0.68, and 0.84 for the spheres with diameters of 10, 13, 17, 22, 28, and 37 mm, respectively, for UHS 2 iterations, a 220 × 220 matrix, and 50-min acquisition. The RC values did not differ with acquisition times down to 20 min. The SNR was the highest for 2 iterations, measured 11.7, 16.6, 17.6, 19.4, 21.9, and 27.7 while the background variability was the lowest (27.59, 27.08, 27.36, 26.44, 30.11, and 33.51%). The lung error was 18%. For the patient dataset, the SNR was 19%, 20%, 24%, and 31% higher for 2 iterations compared to 4 iterations for 20-, 10-, 5-, and 1-min time frames, respectively.
CONCLUSIONS
This study evaluates the NEMA image quality of a long AFOV PET/CT scanner with 90Y. It provides high RC for the smallest sphere compared to other standard AFOV scanners at shorter scan times. The maximum patient SNR was for 2 iterations, 20 min, while 5 min delivers images with acceptable SNR
A novel experimental approach to characterize neutron fields at high- and low-energy particle accelerators.
The characterization of particle accelerator induced neutron fields is challenging but fundamental for research and industrial activities, including radiation protection, neutron metrology, developments of neutron detectors for nuclear and high-energy physics, decommissioning of nuclear facilities, and studies of neutron damage on materials and electronic components. This work reports on the study of a novel approach to the experimental characterization of neutron spectra at two complex accelerator environments, namely the CERF, a high-energy mixed reference field at CERN in Geneva, and the Bern medical cyclotron laboratory, a facility used for multi-disciplinary research activities, and for commercial radioisotope production for nuclear medicine. Measurements were performed through an innovative active neutron spectrometer called DIAMON, a device developed to provide in real time neutron energy spectra without the need of guess distributions. The intercomparison of DIAMON measurements with reference data, Monte Carlo simulations, and with the well-established neutron monitor Berthold LB 6411, has been found to be highly satisfactory in all conditions. It was demonstrated that DIAMON is an almost unique device able to characterize neutron fields induced by hadrons at 120 GeV/c as well as by protons at 18 MeV colliding with different materials. The accurate measurement of neutron spectra at medical cyclotrons during routine radionuclide production for nuclear medicine applications is of paramount importance for the facility decommissioning. The findings of this work are the basis for establishing a methodology for producing controlled proton-induced neutron beams with medical cyclotrons