Bending Strength of Connection Joints of Prestressed Reinforced Concrete Pipe Piles

The connection joint of prestressed concrete pipe piles is a typical steel–concrete structure, and its bending strength has evolved into a critical factor affecting the safety of supporting structures in underground engineering. Based on full-scale bending tests of five specimens of large-diameter prestressed reinforced concrete (PRC) pipe piles and connection joints, as well as the corresponding finite element numerical simulation, the bending bearing and deformation characteristics of connection joints of PRC pipe piles were analyzed, together with the effects of concrete strength, precompression stress, and connection mode of joints. The results showed that the crack resistance of the welded joint of PRC pipe piles was equivalent to that of the pipe pile shaft, but the ultimate bending moment of the joint was about 58–87% of that of the pile shaft. The bending failure mode of the pipe pile joint was mainly manifested in the end plate yielding into a drum shape, with the tension side of the pile hoop and the end plate clearly separated from the pipe pile, and crushed concrete at the upper edge of the pile hoop. The bending strength of the joint can be improved by increasing the bonding strength between the end plates of the joint or embedding Rachel reinforcement in concrete. In addition, synchronously increasing the strength grade and reinforcement ratio of concrete or strengthening the precompression stress of concrete are favorable measures

Optimization of the Physical and Mechanical Properties of Grouting Material for Non-Soil-Squeezing PHC Pipe Pile

The physical and mechanical properties of grouting materials greatly affect the friction resistance and the bearing performance of a non-soil-squeezing PHC pipe pile. Orthogonal tests for four factors at five levels were carried out to optimize the proportion of the water–cement mixture by using Portland cement as a raw material and a water-reducing agent, expansion agent and early-strength agent as additives. The following conclusions were obtained: (1) Both the water–cement ratio and the dosage of water-reducing agent are positively correlated with the fluidity of the water–cement mixture and have the greatest influence on the fluidity, followed by the expansion agent and early-strength agent. The saturation point of the water-reducing agent is 1.5%. (2) The strength of the grouting body decreases linearly with the increase of the water–cement ratio, and the dosage of the water-reducing agent has no obvious effect on the strength. As the dosage of expansion agent increases, the strength of the grouting body decreases rapidly. The expansion agent mainly plays a key role in the middle and late stages of the hardening process of the slurry. Early-strength agents have a greater impact on the early strength, but less on the later strength. When the slurry is solidified for 3 h, the early-strength agent has the greatest impact on the strength with an optimal dosage of 5%. (3) The volume of the grouting body has an inverse relationship with the water–cement ratio, and the optimal amount of expansion agent is 12%. The incorporation of an expansion agent makes the volume increase of the grouting body exceed the volume shrinkage ratio caused by the hardening of the grouting body with a curing time of more than 3 days, ensuring a slight increase in the volume of the grouting body. After 3 days, even though the effect of the expansion agent is gradually weakened, it can still ensure that the volume of the grouting body does not shrink. With the increase of the amount of water-reducing agent, the volume of the grouting body gradually decreases. When the amount of water-reducing agent exceeds 1.5%, the volume of the grouting body no longer decreases. (4) The early-strength agent has almost no effect on the volume of the grouting body. When the curing time is 3 h, the water–cement ratio has the greatest influence on the volume of the grouting body, followed by the water-reducing agent, and, finally, the expansion agent. After 3 h, the water–cement ratio still has the greatest influence, and the influence of the expansion agent gradually exceeds that of the water-reducing agent. The water-reducing agent mainly affects the volume of the grouting body in the water separation stage, and the expansion agent mainly plays a role in the middle and late stages of the slurry solidification. After optimized ratio analysis, the fluidity of the water–cement mixture can be improved, the volume shrinkage ratio rate can be lowered and the early strength can be increased

Optimization of the Physical and Mechanical Properties of Grouting Material for Non-Soil-Squeezing PHC Pipe Pile

The physical and mechanical properties of grouting materials greatly affect the friction resistance and the bearing performance of a non-soil-squeezing PHC pipe pile. Orthogonal tests for four factors at five levels were carried out to optimize the proportion of the water–cement mixture by using Portland cement as a raw material and a water-reducing agent, expansion agent and early-strength agent as additives. The following conclusions were obtained: (1) Both the water–cement ratio and the dosage of water-reducing agent are positively correlated with the fluidity of the water–cement mixture and have the greatest influence on the fluidity, followed by the expansion agent and early-strength agent. The saturation point of the water-reducing agent is 1.5%. (2) The strength of the grouting body decreases linearly with the increase of the water–cement ratio, and the dosage of the water-reducing agent has no obvious effect on the strength. As the dosage of expansion agent increases, the strength of the grouting body decreases rapidly. The expansion agent mainly plays a key role in the middle and late stages of the hardening process of the slurry. Early-strength agents have a greater impact on the early strength, but less on the later strength. When the slurry is solidified for 3 h, the early-strength agent has the greatest impact on the strength with an optimal dosage of 5%. (3) The volume of the grouting body has an inverse relationship with the water–cement ratio, and the optimal amount of expansion agent is 12%. The incorporation of an expansion agent makes the volume increase of the grouting body exceed the volume shrinkage ratio caused by the hardening of the grouting body with a curing time of more than 3 days, ensuring a slight increase in the volume of the grouting body. After 3 days, even though the effect of the expansion agent is gradually weakened, it can still ensure that the volume of the grouting body does not shrink. With the increase of the amount of water-reducing agent, the volume of the grouting body gradually decreases. When the amount of water-reducing agent exceeds 1.5%, the volume of the grouting body no longer decreases. (4) The early-strength agent has almost no effect on the volume of the grouting body. When the curing time is 3 h, the water–cement ratio has the greatest influence on the volume of the grouting body, followed by the water-reducing agent, and, finally, the expansion agent. After 3 h, the water–cement ratio still has the greatest influence, and the influence of the expansion agent gradually exceeds that of the water-reducing agent. The water-reducing agent mainly affects the volume of the grouting body in the water separation stage, and the expansion agent mainly plays a role in the middle and late stages of the slurry solidification. After optimized ratio analysis, the fluidity of the water–cement mixture can be improved, the volume shrinkage ratio rate can be lowered and the early strength can be increased

The Real-Time Automated Monitoring System for Lateral Deflection of Underground Structures

The lateral wall deflection is the most intuitive parameter to reveal the stability and safety of underground excavations. The existing automated approaches, such as to serialize dozens of inclinometers along casing pipes, are too expensive to be applied in most common projects. To guarantee stable automation and lower the costs, a novel system based on strain measurement is proposed in this paper to achieve real-time automated monitoring of underground excavations. The specially designed components are highlighted to benefit the mass industrial production and rapid in situ assembly. By theoretical comparisons, the accuracy and resolution performance of the proposed strategy are demonstrated to be better than those of the traditional manual method. The applicability of the mentioned system was verified by an engineering case, from which it was demonstrated that the proposed system works well to predict the lateral wall deflection of underground excavations. The sensitivity of the monitored results to the boundary conditions is also carefully discussed. The designed system has broad application prospects to provide timely data for safety assessment to prevent the unexpected failure of underground excavation as well as other engineering structures with dangerous lateral deflection or movement

Fragility Analyses of Bridge Structures Using the Logarithmic Piecewise Function-Based Probabilistic Seismic Demand Model

Seismic fragility analysis is an efficient method to evaluate the structural failure probability during earthquake events. Among the existing fragility analysis methods, the probabilistic seismic demand model (PSDM) and the joint probabilistic seismic demand model (JPSDM) are generally used to compute the component and system fragility, respectively. However, the statistical significance behind the parameters related to the current PSDM and JPSDM are not comparable. Aside from that, when calculating the system fragility, the Monte Carlo sampling (MCS) method is time-consuming. To solve the two flaws, in this paper, the logarithm piecewise functions were used to generate the PSDM and the JPSDM, and the MCS was replaced by the univariate conditioning approximation (UCA) method. The concepts and application procedures of the proposed fragility analysis methods were elaborated first. Then, the UCA method was illustrated in detail. Finally, fragility curves of a steel arch truss case study bridge were generated by the proposed method. The research results indicate the following: (1) the proposed methods unify the data sources and statistical significance of the parameters used in the PSDM and the JPSDM; (2) the logarithmic piecewise function-based PSDM sensitively reflects the changing trend of the component’s demand with the fluctuation of the seismic intensity measure; (3) under transverse seismic waves, major injuries happen on the side bearings of the bridge, while slight damage may occur on each pier, and as the seismic intensity measure increases, the side bearings are more likely to be damaged; (4) for the severe damage and the absolute damage of the studied bridge, the system fragility curves are closer to the upper failure bounds; and (5) compared with the MSC method, the accuracy of the UCA method can be guaranteed with less calculation time

A case study on water sealing efficieny of groundwater storage caverns using discrete fracture network method and flow numerical simulation

Containment property is the key to ensuring the safe operation of groundwater-sealed caverns.At present, the main difficulty in studying the water sealing property of groundwater-sealed caverns lies in the strong heterogeneity and anisotropy of fractured rock aquifer.In this paper, a discrete fracture network model is established based on the measured fracture geometry parameters to analyze the fracture development characteristics.Based on the understanding and assumption of the basic law of fracture seepage, a high-precision heterogeneous and anisotropic seepage model is established, and the permeability characteristics of the study area are analyzed.Through the establishment of heterogeneous anisotropic seepage model, the water seal performance of water curtain system is discussed and compared with the traditional homogeneous isotropic seepage model.The model can make up for the deficiencies of the traditional homogeneous isotropic seepage model, and more accurately evaluate the storage leakage risk caused by the heterogeneity and anisotropy of fractured rock mass

Simplified Seismic Loss Estimation of RC Frame using Component-performance-based Methodology

A framework of simplified probabilistic seismic loss estimation of RC frame using component- performance -based methodology was presented in this paper. Firstly, component- performance -based methodology was introduced, and component performance level was measured using elasto-plastic rotation angle of structural component. Then structural performance level was determined by the statistics of damaged components distribution. Additionally, the relationship between the structural performance level and loss ratio of RC frame was established. Last, expected seismic loss ratio of 3-storey RC frame was studied in detail. This study reveals that the simplified probabilistic framework proposed herein could be used in RC frame

Overexpression of PTPN2 in Visceral Adipose Tissue Ameliorated Atherosclerosis via T Cells Polarization Shift in Diabetic Apoe-/- Mice

Background/Aims: Dysregulated inflammation in adipose tissue, marked by increased pro-inflammatory T-cell accumulation and reduced regulatory T cells (Treg), contributes to diabetes-associated insulin resistance and atherosclerosis. However, the molecular mechanisms underlying T-cell-mediated inflammation in adipose tissue remain largely unknown. Methods: Sixty apolipoprotein E (ApoE-/-) mice were randomly divided into chow and diabetes groups. Diabetes was induced by a high-fat and high-sugar diet combined with low-dose streptozotocin. Then we transferred a recombinant adenovirus carrying the protein tyrosine phosphatase non-receptor type 2 (PTPN2) gene into epididymal white adipose tissue (EWAT) of ApoE-/- mice. After transfection, all mice were euthanized to evaluate the effects of PTPN2 on T cells polarization and atherosclerosis. Results: PTPN2 was downregulated in EWAT of diabetic ApoE-/- mice. PTPN2 overexpression in EWAT reversed the high Th1/Treg and Th17/Treg ratios in EWAT of diabetic mice. In addition, PTPN2 overexpression in EWAT could significantly reduce macrophages infiltration, the ratio of M1/M2 macrophages and the expression of pro-inflammatory cytokines in EWAT, improving insulin resistance. In aortic root lesions, the vulnerability index were significantly decreased by overexpression of PTPN2 in EWAT. Conclusion: These data suggested that PTPN2 overexpression in EWAT would inhibit systemic inflammation and increase the plaque stability via T cells polarization shift in diabetic mice

O polimorfismo do gene AKL7 está associado ao risco de síndrome metabólica e à remodelação cardiovascular ALK7 gene polymorphism is associated with metabolic syndrome risk and cardiovascular remodeling

FUNDAMENTO: Quinase Tipo Receptor de Ativina 7 (ALK7) é um tipo de receptor I para a superfamília TGF-&#946; e recentemente apresentou ter uma função importante na manutenção de homeostase metabólica. OBJETIVO: Investigar a associação do polimorfismo do gene ALK7 à síndrome metabólica (SMet) e remodelação cardiovascular em pacientes com SMet. MÉTODOS: O polimorfismo de nucleotídeo único rs13010956 no gene ALK7 foi genotipado em 351 indivíduos chineses submetidos à ultrassonografia cardíaca e das carótidas. As associações do polimorfismo do gene ALK7 ao fenótipo e aos parâmetros da síndrome metabólica e características ultrassônicas cardiovasculares foram analisadas. RESULTADOS: O polimorfismo de rs13010956 no gene ALK7 foi considerado significativamente relacionado ao fenótipo de SMet em mulheres (p < 0,05) e significativamente associado à pressão sanguínea em populações totais (p < 0,05) e femininas (p < 0,01). Outras análises revelaram que rs13010956 estava associado à média da espessura íntima-média de artérias carótidas em mulheres (p < 0,05). Após o controle do índice de massa corporal, pressão arterial, glicemia em jejum e triglicérides, o rs13010956 também foi considerado significativamente associado ao índice de massa do ventrículo esquerdo em populações totais (p < 0,05) e femininas (p < 0,05). CONCLUSÃO: Nossos achados sugeriram que o polimorfismo de rs13010956 do gene ALK7 estava significativamente vinculado ao risco de SMet em mulheres e pode estar envolvido na remodelação cardiovascular em pacientes com SMet.<br>BACKGROUND: Activin receptor-like kinase 7 (ALK7) is a type I receptor for the TGF-&#946; superfamily and has recently been demonstrated to play an important role in the maintenance of metabolic homeostasis. OBJECTIVE: To investigate the association of the ALK7 gene polymorphism with metabolic syndrome (MetS) and cardiovascular remodeling in MetS patients. METHODS: The single nucleotide polymorphism rs13010956 in the ALK7 gene was genotyped in 351 Chinese subjects undergoing carotid and cardiac ultrasonography. The associations of the ALK7 gene polymorphism with the MetS phenotype, MetS parameters, and cardiovascular ultrasonic features were analyzed. RESULTS: The rs13010956 polymorphism in the ALK7 gene was found to be significantly associated with the MetS phenotype in females (p < 0.05) and was also significantly associated with blood pressure in the total (p < 0.05) and female populations (p < 0.01). Further analysis revealed that rs13010956 was associated with mean intima-media thickness of the carotid arteries in females (p < 0.05). After control for body mass index, blood pressure, fasting blood glucose, and triglycerides, rs13010956 was also found to be significantly associated with left ventricular mass index in the total (p < 0.05) and female populations (p < 0.05). CONCLUSION: Our findings suggested that the ALK7 gene polymorphism rs13010956 was significantly associated with MetS risk in females and may be involved in cardiovascular remodeling in MetS patients