195 research outputs found

    From Copy to Practice: Follower’s Learning Behavior in Forex Social Trading

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    Forex social trading platforms endows novice investors with opportunities to trade on foreign exchange markets by mimicking the investment strategies of sophisticated traders. But concurrently, the copy-trading mechanism underlying these platforms foster a conducive learning environment whereby inexperience followers could evolve into independent traders by observing and learning from the trading behaviors of prominent traders. Drawing on observational learning theory, we advance learning efficiency and effectiveness as focal yardsticks to encapsulate followers’ learning performance and explore their effects on the profitability of followers’ first independent trades. Preliminary analysis conducted on a leading forex social trading platform reveals that traders’ trading consistency amplifies followers’ learning efficiency whereas traders’ profitability bolsters followers’ learning effectiveness. Furthermore, while our empirical findings attest to the criticality of learning effectiveness on followers’ ability to profit from their initial independent trades, speeding up the learning process may not guarantee better performance

    Research on the Heating of Deicing Fluid in a New Reshaped Coiled Tube

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    Aircraft ground deicing operation is significant to ensure civil flight safety in winter. Helically coiled tube is the important heat exchanger in Chinese deicing fluid heating system. In order to improve the deicing efficiency, the research focuses on heat transfer enhancement of deicing fluid in the tube. Based on the field synergy principle, a new reshaped tube (TCHC) is designed by ring-rib convex on the inner wall. Deicing fluid is high viscosity ethylene-glycol-based mixture. Because of the power function relation between high viscosity and temperature, viscosity has a negative influence on heat transfer. The number of ring-ribs and inlet velocity are two key parameters to the heat transfer performance. For both water and ethylene glycol, the outlet temperature rises when the number of ring-ribs increases to a certain limit. However, the increasing of velocity reduces heating time, which results in lower outlet temperature. The heating experiment of the original tube is conducted. The error between experiment and simulation is less than 5%. The outlet temperature of TCHC increases by 3.76%. As a result, TCHC efficiently promotes the coordination of velocity and temperature fields by changing the velocity field. TCHC has enhanced heat transfer of high viscosity deicing fluid

    NH2+ implantations induced superior hemocompatibility of carbon nanotubes

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    NH(2)(+) implantation was performed on multiwalled carbon nanotubes (MWCNTs) prepared by chemical vapor deposition. The hemocompatibility of MWCNTs and NH(2)(+)-implanted MWCNTs was evaluated based on in vitro hemolysis, platelet adhesion, and kinetic-clotting tests. Compared with MWCNTs, NH(2)(+)-implanted MWCNTs displayed more perfect platelets and red blood cells in morphology, lower platelet adhesion rate, lower hemolytic rate, and longer kinetic blood-clotting time. NH(2)(+)-implanted MWCNTs with higher fluency of 1 × 10(16) ions/cm(2) led to the best thromboresistance, hence desired hemocompatibility. Fourier transfer infrared and X-ray photoelectron spectroscopy analyses showed that NH(2)(+) implantation caused the cleavage of some pendants and the formation of some new N-containing functional groups. These results were responsible for the enhanced hemocompatibility of NH(2)(+)-implanted MWCNTs

    Grassland Rehabilitation through Re-Designing Livestock Management Systems

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    Grasslands are one of the most important land types supplying critical ecosystem services including feed for livestock grazing. They occupy ~54% of the world’s ice-free land surface. China contains the third largest area of grassland in the world, ~400 M ha, ~40% of China’s land surface. Chinese grasslands are severely degraded primarily due to overgrazing, which contributes to local poverty because of poor livestock production. To both recover the degraded grassland and to enhance the local herders’ income, a large farm-scale experiment was conducted in a desert steppe of Inner Mongolia, China from 2007 to 2012. We used a baseline survey, production models, and extension with government and private companies to test a redesigned grassland livestock management system. The new system employed summer grazing, winter greenhouse shed feeding, a reduction of overall stocking rate, lambing in summer (July), livestock infrastructure structure improvements, use of animal nutrient supplements, and incorporating crossbred Dorper and Mongolian sheep. This system showed positive advantages on animal production and household net income and transformed livestock production from a survival to a production enterprise. Of critical additional importance was that grassland rehabilitation occurred with the new management system, albeit slower than the more immediate positive changes to animal performance and herder net incomes. The integration of science, government and industry were key for this successful large-scale farm experiment

    Effect of Interaction between Protein Phosphorylation and S-Nitrosylation on Mutton Tenderness during Postmortem Storage

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    Postmortem mutton longissimus dorsi was minced and treated separately with phosphatase inhibitor, kinase inhibitor, S-nitrosoglutathione and nitric oxide synthase (NOS) inhibitor to control the degrees of phosphorylation and S-nitrosylation. The effect of interaction between protein phosphorylation and S-nitrosylation on mutton tenderness during postmortem storage were investigated by analyzing the changes in the phosphorylation level, S-nitrosylation level, pH, myofibrillar fragmentation index (MFI), desmin and troponin-T degradation of the treated mutton samples during storage at 4 ℃. The results indicated that phosphorylation levels were significantly higher (P < 0.05) in the phosphorylation-controlled group than in the phosphorylation and S-nitrosylation-controlled group in the early (0–12 h) and late (48–72 h) stages of storage, suggesting that protein S-nitrosylation inhibited its phosphorylation. When phosphorylation and S-nitrosylation modifications acted simultaneously, phosphorylation modification was dominant in affecting pH and its effect could be further enhanced by S-nitrosylation. On the contrary, S-nitrosylation played a major role in destroying the internal structure of myofibrillar proteins in mutton longissimus dorsi. When they occurred simultaneously, protein phosphorylation inhibited its S-nitrosylation; conversely, protein S-nitrosylation may promote the inhibitory effect of protein phosphorylation on desmin degradation. During postmortem storage, the interaction between protein phosphorylation and S-nitrosylation varied at different reaction periods, but both ultimately resulted in a decrease of troponin-T degradation. In conclusion, the interaction between protein phosphorylation and S-nitrosylation negatively influences the tenderness of mutton during postmortem aging

    Development and validation of risk prediction model for premenstrual syndrome in nurses: results from the nurses-based the TARGET cohort study

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    ObjectivePremenstrual syndrome (PMS) stands as a significant concern within the realm gynecological disorders, profoundly impacting women of childbearing age in China. However, the elusive nature of its risk factors necessitates investigation. This study, therefore, is dedicated to unraveling the intricacies of PMS by focusing on nurses, a cohort with unique occupational stressors, to develop and validate a predictive model for assessing the risk of PMS.MethodsThis investigation employed a multi-center cross-sectional analysis drawing upon data from the TARGET Nurses’ health cohort. Utilizing online survey versions of the Premenstrual Syndrome Scale (PMSS), a comprehensive dataset encompassing physiological, social, psychological, occupational, and behavioral variables was collected from 18,645 participants. A stepwise multivariate logistic regression analysis was conducted to identify independent risk factors for PMS. Furthermore, a refined variable selection process was executed, combining the Least Absolute Shrinkage and Selection Operator (LASSO) method with 10-fold cross-validation. The visualization of the risk prediction model was achieved through a nomogram, and its performance was evaluated using the C index, receiver operating characteristic (ROC) curves, and the calibration curves.ResultsAmong the diverse variables explored, this study identified several noteworthy predictors of PMS in nurses, including tea or coffee consumption, sleep quality, menstrual cycle regularity, intermenstrual bleeding episodes, dysmenorrhea severity, experiences of workplace bullying, trait coping style, anxiety, depression and perceived stress levels. The prediction model exhibited robust discriminatory power, with an area under the curve of 0.765 for the training set and 0.769 for the test set. Furthermore, the calibration curve underscored the model’s high degree of alignment with observed outcomes.ConclusionThe developed model showcases exceptional accuracy in identifying nurses at risk of PMS. This early alert system holds potential to significantly enhance nurses’ well-being and underscore the importance of professional support

    Contezolid, a novel oxazolidinone antibiotic, may improve drug-related thrombocytopenia in clinical antibacterial treatment

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    One of the major limitations in the clinical use of existing oxazolidinone antibiotics is their characteristic adverse reactions, in particular thrombocytopenia. In anti-infective treatment, if patients are suspected of having drug-induced thrombocytopenia, the first step is to immediately discontinue the offending drug. Even in patients with severe infections, the antibacterial drug may need to be changed or the antibacterial treatment may need to be discontinued because thrombocytopenia may have a more serious clinical prognosis. In addition, if the patient needs to continue antibacterial treatment after discharge, the lack of conditions for monitoring platelet levels may also pose hidden dangers to the patient. Contezolid is an orally administered oxazolidinone antibacterial agent approved by the National Medical Products Administration of China in 2021. We found that contezolid may have an improved safety profile with a significantly reduced potential for myelosuppression based on the results of our observational clinical study. In this article, we review the advantages of contezolid as a new oxazolidinone antibiotic and describe three typical clinical cases of patients who experienced drug-induced thrombocytopenia after using linezolid. The platelet levels of these different patients were all significantly improved to varying degrees after initiation of contezolid treatment
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