The Effect Prediction of Acquiring New Customers Based on Gongtianxia\u27s Dutch Auction

With the development of the Mobile Internet, many E-commerce sites are using mobile applications to promote marketing and to acquire new customers, mobile marketing activities has become one of the best ways to expand market share. Therefore, it’s very concerned to study how to acquire new customers effectively in the early stage of entering the market. Gongtianxia’s WeChat public platform is committed to attract new customers through Mobile Internet. Gongtianxia adopted two kinds of Dutch auctions, ‘7-day auction’ and ‘15-minute auction’ respectively, which can effectively acquire new customers. This study collected more than 80000 of records, 738 pieces of auction data from June 2015 to December 2015 in Gongtianxia’s Dutch auctions, by collecting, sorting and analyzing the auction data, and established a BPNN simulation and prediction model. The prediction model for each auction data can be used to predict the customer number, cost and blowout price in advance of the auction. This study can improve customer-attracting effect of mobile application and make a theoretical complement for Dutch auction as Mobile Internet sale, and enriches the research for acquiring new customers through Mobile Internet

Key-Controlled Order-Preserving Encryption

In this paper we study order-preserving encryption (OPE), a primitive in the database community for allowing efficient range queries on ecrypted data. OPE was suggested by Agrawal et al [1], and was throughly studied by Boldyreva et al [2]. In this paper we present a practical OPE scheme, which is a key-controlled algorithm, based on simple computation. A primary analysis shows that our algorithm is secure enoug

Polarization splitter rotator on thin film lithium niobate based on multimode interference

Polarization splitter-rotators (PSRs) are the key elements to realize on-chip polarization manipulation. Current PSRs on thin film lithium niobate (TFLN) rely on sub-micron gaps to realize modes separation, which increase the difficulties of lithography and etching. In this paper, a polarization splitter-rotator on TFLN based on multimode interference (MMI) is demonstrated. Mode division is achieved by an MMI-based mode demultiplexer. The feature size of the PSR is 1.5 {\mu}m, which can be fabricated with low priced i-line contact aligners. Experimental results show a polarization extinction ratio (PER) > 20 dB and insertion loss (IL) <1.5 dB are achieved in a wavelength range of 1542-1600 nm for TE-polarized light. And a PER > 9.5 dB and an IL <3.0 dB are achieved in a wavelength range of 1561-1600 nm for TM-polarized light. This PSR could find application in the low-cost fabrication of dual-polarization TFLN integrated photonic devices

Feature Fusion from Head to Tail for Long-Tailed Visual Recognition

The imbalanced distribution of long-tailed data presents a considerable challenge for deep learning models, as it causes them to prioritize the accurate classification of head classes but largely disregard tail classes. The biased decision boundary caused by inadequate semantic information in tail classes is one of the key factors contributing to their low recognition accuracy. To rectify this issue, we propose to augment tail classes by grafting the diverse semantic information from head classes, referred to as head-to-tail fusion (H2T). We replace a portion of feature maps from tail classes with those belonging to head classes. These fused features substantially enhance the diversity of tail classes. Both theoretical analysis and practical experimentation demonstrate that H2T can contribute to a more optimized solution for the decision boundary. We seamlessly integrate H2T in the classifier adjustment stage, making it a plug-and-play module. Its simplicity and ease of implementation allow for smooth integration with existing long-tailed recognition methods, facilitating a further performance boost. Extensive experiments on various long-tailed benchmarks demonstrate the effectiveness of the proposed H2T. The source code is available at https://github.com/Keke921/H2T.Comment: Accepted to AAAI24, similar to the conference version. Add the supplementr

PL-015 Aerobic exercise increases BKCa channel expression to enhance tracheal smooth muscle relaxation in a murine asthma model: There is no full paper associated with this abstract

Objective Increasing evidence has shown that moderate-intensity aerobic exercise training reduces airway hyperresponsiveness (AHR) in patients with asthma. However, the mechanisms underlying exercise-induced improvements in smooth muscle contractility have not been fully elucidated. Large-conductance Ca2+-activated K+&nbsp;channels (BKCa) are expressed broadly on smooth muscle cells and play an important role in the regulation of smooth muscle contraction. We tested the hypothesis that exercise training increases the contribution of BKCa&nbsp;channel to tracheal smooth muscle relaxation in in ovalbumin (OVA)-challenged asthmatic rats. Methods Rats were sensitized/challenged with OVA or saline and exercised at a moderate intensity 5 times/week for 4 weeks. Tracheal smooth muscle contractility was tested. Membrane potential of primary cultured tracheal smooth muscle cells was measured. In addition, western immunoblotting was performed to study the expression levels of BKCa&nbsp;channel protein. Results The contraction of rat airway smooth muscle induced by carbachol was significantly increased with asthma and exercise training reversed this alteration. Application of BKCa&nbsp;channel agonist, NS1619, induced tracheal smooth muscle relaxation. NS1619-induced relaxation was decreased in asthmatic rats, however exercise training significantly increased NS1619-induced relaxation. In primary cultured smooth muscle cells, NS1619-induced membrane potential was reduced with asthma and this alteration was diminished after exercise training. Additionally, western blotting revealed that the protein expression of BKCa&nbsp;was reduced in asthmatic group and aerobic exercise significantly improved BKCa&nbsp;expression. Conclusions The present study reveals that aerobic exercise training increases BKCa&nbsp;expression on tracheal smooth muscle, which partly underlies the beneficial effect of exercise on improving airway smooth muscle relaxation in asthma

2D MXene Ti3C2Tx nanosheets in the development of a mechanically enhanced and efficient antibacterial dental resin composite

The bacterial accumulation at the margins of dental resin composites is a main cause of secondary caries, which may further lead to prosthodontic failure. In this regard, this study for the first time incorporated 2D MXene Ti3C2Tx nanosheets (NSs) into epoxy resin at different mass ratios (0, 0.5, 1.0, and 2.0 wt%) by solution blending and direct curing for dental applications. Compared to the pure resin, the as-fabricated MXene/resin composite not only exhibited improved mechanical and abrasive results but also displayed gradually improved antibacterial activity with MXene loading which was further enhanced by illumination in natural light due to the high photothermal efficiency of MXene. In addition, the cytotoxicity result demonstrated that the MXene-modified resin did not cause severe damage to normal cells. This novel MXene/resin nanocomposite could pave the way for new designs for high-performance, multifunctional nanocomposites to effectively protect dental health in daily life

Epidemiologic trends and survival of early-onset gastroenteropancreatic neuroendocrine neoplasms

BackgroundThe epidemiologic trends and survival related to early-onset gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) have not been well explored.MethodsTrends in the incidence and incidence-based mortality of early-onset GEP-NENs between 1975 and 2018 were obtained from the Surveillance, Epidemiology, and End Results database, and were stratified by age, sex, race, tumor site, stage, and grade. Associated population data were used to determine overall survival (OS) and independent prognostic factors for patients with early-onset GEP-NENs.ResultsA total of 17299 patients diagnosed with early-onset GEP-NENs were included in this study. Results revealed an increase in the incidence (5.95% per year, 95% confidence interval (CI), 5.75-6.14%) and incidence-based mortality (4.24% per year, 95% CI, 3.92-4.56%) for early-onset GEP-NENs from 1975 to 2018, with higher rates of increase than those of later-onset GEP-NENs (incidence: 4.45% per year, 95% CI, 4.38-4.53; incidence-based mortality: 4.13% per year, 95% CI, 3.89-4.37; respectively). Increases in incidence were observed across all age, races, tumor sites, grades, and stages, except for patients with unknown stage. Compared to those with later-onset GEP-NENs, a higher proportion of female gender (54.5% vs. 49.0%, p &lt;0.001), well-differentiated tumor (31.1% vs. 28.0%, p &lt;0.05), and localized disease (55.2% vs. 46.7%, p &lt;0.05) were observed in the cohort of patients with early-onset GEP-NENs. Moreover, early-onset GEP-NENs exhibited a superior overall survival in comparison to later-onset GEP-NENs, irrespective of tumor site, grade, or stage (p &lt;0.0001). Multivariable survival analysis identified that race, marital status, stage, grade, chemotherapy, and primary site were significantly correlated with OS in individuals with early-onset GEP-NENs.ConclusionsThe incidence and incidence-based mortality rates of early-onset GEP-NENs have steadily increased over time, with higher rates of increase than those of later-onset GEP-NENs. The clinical characteristics and survival were different between early-onset and later-onset GEP-NENs groups. Race, marital status, stage, grade, chemotherapy, and primary site were independent prognostic factors for early-onset GEP-NENs. Further investigations are warranted to better understand the characteristics of this disease subgroup

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum