New Properties and Applications of Polyvinylidene-Based Ferroelectric Polymer

There are different kinds of novel properties and applications of polyvinylidene difluoride (PVDF)-based ferroelectric polymer films. Several issues associated with the structure, properties, and applications of PVDF-based ferroelectric polymer films are discussed. The main achievements of the research include high electric tunability of relaxor ferroelectric Langmuir–Blodgett (LB) terpolymer films, the creep process of the domain switching in poly(vinylidene fluoride-trifluoroethylene) ferroelectric thin films, transition from relaxor to ferroelectric-like phase in poly(vinylidene fluoride-trifluoroethylene -chlorofluoroethylene) terpolymer ultrathin films, abnormal polarization switching of relaxor terpolymer films at low temperatures, huge electrocaloric effect in LB ferroelectric polymer thin films, self-polarization in ultrathin LB polymer films, enhanced dielectric and ferroelectric properties in artificial polymer multilayers, and transition of polarization switching from extrinsic to intrinsic in ultrathin PVDF homopolymer films

A Monte Carlo study of temperature-programmed desorption spectra with attractive lateral interactions

We present results of a Monte Carlo study of temperature-programmed desorption in a model system with attractive lateral interactions. It is shown that even for weak interactions there are large shifts of the peak maximum temperatures with initial coverage. The system has a transition temperature below which the desorption has a negative order. An analytical expression for this temperature is derived. The relation between the model and real systems is discussed.Comment: Accepted for publication in Phys.Rev.B15, 10 pages (REVTeX), 2 figures (PostScript); discussion about Xe/Pt(111) adde

The nearly Newtonian regime in Non-Linear Theories of Gravity

The present paper reconsiders the Newtonian limit of models of modified gravity including higher order terms in the scalar curvature in the gravitational action. This was studied using the Palatini variational principle in [Meng X. and Wang P.: Gen. Rel. Grav. {\bf 36}, 1947 (2004)] and [Dom\'inguez A. E. and Barraco D. E.: Phys. Rev. D {\bf 70}, 043505 (2004)] with contradicting results. Here a different approach is used, and problems in the previous attempts are pointed out. It is shown that models with negative powers of the scalar curvature, like the ones used to explain the present accelerated expansion, as well as their generalization which include positive powers, can give the correct Newtonian limit, as long as the coefficients of these powers are reasonably small. Some consequences of the performed analysis seem to raise doubts for the way the Newtonian limit was derived in the purely metric approach of fourth order gravity [Dick R.: Gen. Rel. Grav. {\bf 36}, 217 (2004)]. Finally, we comment on a recent paper [Olmo G. J.: Phys. Rev. D {\bf 72}, 083505 (2005)] in which the problem of the Newtonian limit of both the purely metric and the Palatini formalism is discussed, using the equivalent Brans--Dicke theory, and with which our results partly disagree.Comment: typos corrected, replaced to match published versio

Gravitational Lensing and f(R) theories in the Palatini approach

We investigate gravitational lensing in the Palatini approach to the f(R) extended theories of gravity. Starting from an exact solution of the f(R) field equations, which corresponds to the Schwarzschild-de Sitter metric and, on the basis of recent studies on this metric, we focus on some lensing observables, in order to evaluate the effects of the non linearity of the gravity Lagrangian. We give estimates for some astrophysical events, and show that these effects are tiny for galactic lenses, but become interesting for extragalactic ones.Comment: 7 Pages, RevTex, 1 eps figure; references added; revised to match the version accepted for publication in General Relativity and Gravitatio

Checkpoint inhibition reduces the threshold for Drug-Specific T-Cell priming and increases the incidence of sulfasalazine hypersensitivity

An emerging clinical issue associated with immune-oncology agents is the collateral effects on the tolerability of concomitant medications. One report of this phenomenon was the increased incidence of hypersensitivity reactions observed in patients receiving concurrent immune checkpoint inhibitors (ICIs) and sulfasalazine (SLZ). Thus, the aim of this study was to characterize the T cells involved in the pathogenesis of such reactions, and recapitulate the effects of inhibitory checkpoint blockade on de-novo priming responses to compounds within in vitro platforms. A regulatory competent human dendritic cell/T-cell coculture assay was used to model the effects of ICIs on de novo nitroso sulfamethoxazole- and sulfapyridine (SP) (the sulfonamide component of SLZ) hydroxylamine-specific priming responses. The role of T cells in the pathogenesis of the observed reactions was explored in 3 patients through phenotypic characterization of SP/sulfapyridine hydroxylamine (SPHA)-responsive T-cell clones (TCC), and assessment of cross-reactivity and pathways of T-cell activation. Augmentation of the frequency of responding drug-specific T cells and intensity of the T-cell response was observed with PD-1/PD-L1 blockade. Monoclonal populations of SP- and SPHA-responsive T cells were isolated from all 3 patients. A core secretory effector molecule profile (IFN-γ, IL-13, granzyme B, and perforin) was identified for SP and SPHA-responsive TCC, which proceeded through Pi and hapten mechanisms, respectively. Data presented herein provides evidence that drug-responsive T cells are effectors of hypersensitivity reactions observed in oncology patients administered ICIs and SLZ. Perturbation of drug-specific T-cell priming is a plausible explanation for clinical observations of how an increased incidence of these adverse events is occurring

Entropy and universality of Cardy-Verlinde formula in dark energy universe

We study the entropy of a FRW universe filled with dark energy (cosmological constant, quintessence or phantom). For general or time-dependent equation of state $p=w\rho$ the entropy is expressed in terms of energy, Casimir energy, and $w$. The correspondent expression reminds one about 2d CFT entropy only for conformal matter. At the same time, the cosmological Cardy-Verlinde formula relating three typical FRW universe entropies remains to be universal for any type of matter. The same conclusions hold in modified gravity which represents gravitational alternative for dark energy and which contains terms growing at low curvature. It is interesting that BHs in modified gravity are more entropic than in Einstein gravity. Finally, some hydrodynamical examples testing new shear viscosity bound, which is expected to be the consequence of the holographic entropy bound, are presented for the early universe in the plasma era and for the Kasner metric. It seems that the Kasner metric provides a counterexample to the new shear viscosity bound.Comment: LaTeX file, 39 pages, references are adde

Sensitivity of deexcitation energies of superdeformed secondary minima to the density dependence of symmetry energy with the relativistic mean-field theory

The relationship between deexcitation energies of superdeformed secondary minima relative to ground states and the density dependence of the symmetry energy is investigated for heavy nuclei using the relativistic mean field (RMF) model. It is shown that the deexcitation energies of superdeformed secondary minima are sensitive to differences in the symmetry energy that are mimicked by the isoscalar-isovector coupling included in the model. With deliberate investigations on a few Hg isotopes that have data of deexcitation energies, we find that the description for the deexcitation energies can be improved due to the softening of the symmetry energy. Further, we have investigated deexcitation energies of odd-odd heavy nuclei that are nearly independent of pairing correlations, and have discussed the possible extraction of the constraint on the density dependence of the symmetry energy with the measurement of deexcitation energies of these nuclei.Comment: 14 pages, 3 figure

Evolution of arboreality and fossoriality in squirrels and aplodontid rodents: Insights from the semicircular canals of fossil rodents

Reconstructing locomotor behaviour for fossil animals is typically done with postcranial elements. However, for species only known from cranial material, locomotor behaviour is difficult to reconstruct. The semicircular canals (SCCs) in the inner ear provide insight into an animal's locomotor agility. A relationship exists between the size of the SCCs relative to body mass and the jerkiness of an animal's locomotion. Additionally, studies have also demonstrated a relationship between SCC orthogonality and angular head velocity. Here, we employ two metrics for reconstructing locomotor agility, radius of curvature dimensions and SCC orthogonality, in a sample of twelve fossil rodents from the families Ischyromyidae, Sciuridae and Aplodontidae. The method utilizing radius of curvature dimensions provided a reconstruction of fossil rodent locomotor behaviour that is more consistent with previous studies assessing fossil rodent locomotor behaviour compared to the method based on SCC orthogonality. Previous work on ischyromyids suggests that this group displayed a variety of locomotor modes. Members of Paramyinae and Ischyromyinae have relatively smaller SCCs and are reconstructed to be relatively slower compared to members of Reithroparamyinae. Early members of the Sciuroidea clade including the sciurid Cedromus wilsoni and the aplodontid Prosciurus relictus are reconstructed to be more agile than ischyromyids, in the range of extant arboreal squirrels. This reconstruction supports previous inferences that arboreality was likely an ancestral trait for this group. Derived members of Sciuridae and Aplodontidae vary in agility scores. The fossil squirrel Protosciurus cf. rachelae is inferred from postcranial material as arboreal, which is in agreement with its high agility, in the range of extant arboreal squirrels. In contrast, the fossil aplodontid Mesogaulus paniensis has a relatively low agility score, similar to the fossorial Aplodontia rufa, the only living aplodontid rodent. This result is in agreement with its postcranial reconstruction as fossorial and with previous indications that early aplodontids were more arboreal than their burrowing descendants

Measuring Parton Densities in the Pomeron

We present a program to measure the parton densities in the pomeron using diffractive deep inelastic scattering and diffractive photoproduction, and to test the resulting parton densities by applying them to other processes such as the diffractive production of jets in hadron-hadron collisions. Since QCD factorization has been predicted NOT to apply to hard diffractive scattering, this program of fitting and using parton densities might be expected to fail. Its success or failure will provide useful information on the space-time structure of the pomeron.Comment: Contains revisions based on Phys. Rev. D referee comments. RevTeX version 3, epsf, 31 pages. Uuencoded compressed postscript figures appended. Uncompressed postscript files available at ftp://ftp.phys.psu.edu/pub/preprint/psuth136

Mass spectrum of the axial-vector hidden charmed and hidden bottom tetraquark states

In this article, we perform a systematic study of the mass spectrum of the axial-vector hidden charmed and hidden bottom tetraquark states using the QCD sum rules, and identify the $Z^+(4430)$ as an axial-vector tetraquark state tentatively.Comment: 24 pages, 38 figures, slight revisio