Simulations of the optical alignment system for the LHCb outer tracker detector

A design of an optical alignment monitoring system for the outer trakcer stations in LHCb experiment is analyzed by means of the error propagation and geometrical reconstruction software SIMULGEO. The optimum solution for the monitoring system is chosen by comparing results obtained for various configurations of the sytem

Test results of the RASNIK optical alignment monitoring system for the LHCb outer tracker detector

We present the results from tests of the RASNIK optical alignment monitoring system installed on a 5.6 m long optical bench with movable platforms. The measurements of the stability, resolution and linearity of the system show that it performs according to specifications. The effects of temperature gradients were also investigated. All the results show that the system is well adapted to the LHCb Outer Tracker needs

Lipid Profiles in Out-of-Hospital Sudden Unexpected Death

Objective: To determine the association between serum lipid measurements and the occurrence of out-of-hospital sudden unexpected death (OHSUD). Patients and Methods: We compared 139 OHSUD cases (43 female patients [30.9%]) and 968 controls (539 female patients [55.7%]) from Wake County, North Carolina, from March 1, 2013, through February 28, 2015. Individuals were included if they were aged 18 to 64 years and had lipid measurements in the 5 years before their death (cases) or the most recent health care encounter (controls). Covariates were abstracted from medical records for all subjects, and those with triglyceride (TG) levels greater than 400 mg/dL (to convert to mmol/L, multiply by 0.0259) were excluded for low-density lipoprotein (LDL)–related analyses. Results: By linear regression using age- and sex-adjusted models, cases of OHSUD had lower adjusted mean total cholesterol (170.3±52.2 mg/dL vs 188.9±39.7 mg/dL; P<.001), LDL cholesterol (90.9±39.6 mg/dL vs 109.6±35.2 mg/dL; P<.001), and non–high-density lipoprotein (HDL) (121.6±49.8 mg/dL vs 134.3±39.6 mg/dL; P<.001) levels and a higher adjusted TG/HDL-C ratio (4.7±7 vs 3±2.7; P<.001) than did controls. By logistic regression using age- and sex-adjusted models, the odds of OHSUD were elevated per unit increase in TG/HDL-C ratio (1.08; 95% CI, 1.03-1.12). Conclusion: Out-of-hospital sudden unexpected death cases had more favorable levels of total cholesterol, LDL cholesterol, and non-HDL, possibly indicating a lack of association between traditional lipid cardiovascular risk factors and sudden unexpected death. A comparatively elevated TG/HDL-C ratio in cases may corroborate an evolving hypothesis of how vasoactive and prothrombotic remnant-like lipoprotein particles contribute to sudden unexpected death

Evolution of market shares with repeated purchases and heterogeneous network externalities

Technology adoption, Network externalities, Market share dynamics, L1, L13, D43,

Recommendations for Providers on Person-Centered Approaches to Assess and Improve Medication Adherence

Medication non-adherence is a significant clinical challenge that adversely affects psychosocial factors, costs, and outcomes that are shared by patients, family members, providers, healthcare systems, payers, and society. Patient-centered care (i.e., involving patients and their families in planning their health care) is increasingly emphasized as a promising approach for improving medication adherence, but clinician education around what this might look like in a busy primary care environment is lacking. We use a case study to demonstrate key skills such as motivational interviewing, counseling, and shared decision-making for clinicians interested in providing patient-centered care in efforts to improve medication adherence. Such patient-centered approaches hold considerable promise for addressing the high rates of non-adherence to medications for chronic conditions